GABARAPL2: Difference between revisions
Jump to navigation
Jump to search
m Robot: Automated text replacement (-{{WikiDoc Cardiology Network Infobox}} +, -<references /> +{{reflist|2}}, -{{reflist}} +{{reflist|2}}) |
m Bot: HTTP→HTTPS |
||
Line 1: | Line 1: | ||
{{Infobox_gene}} | |||
{{ | '''Gamma-aminobutyric acid receptor-associated protein-like 2''' is a [[protein]] that in humans is encoded by the ''GABARAPL2'' [[gene]].<ref name="pmid11414770">{{cite journal | vauthors = Xin Y, Yu L, Chen Z, Zheng L, Fu Q, Jiang J, Zhang P, Gong R, Zhao S | title = Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein | journal = Genomics | volume = 74 | issue = 3 | pages = 408–13 | date = Jun 2001 | pmid = 11414770 | pmc = | doi = 10.1006/geno.2001.6555 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: GABARAPL2 GABA(A) receptor-associated protein-like 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11345| accessdate = }}</ref> | ||
| | |||
| | |||
| | |||
| | |||
| | |||
}} | |||
== Interactions == | |||
< | GABARAPL2 has been shown to [[Protein-protein interaction|interact]] with [[ULK1]],<ref name=pmid11146101>{{cite journal | vauthors = Okazaki N, Yan J, Yuasa S, Ueno T, Kominami E, Masuho Y, Koga H, Muramatsu M | title = Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation | journal = Brain Research. Molecular Brain Research | volume = 85 | issue = 1-2 | pages = 1–12 | date = Dec 2000 | pmid = 11146101 | doi = 10.1016/S0169-328X(00)00218-7 }}</ref> [[ATG4B]],<ref name="pmid17353931">{{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}</ref><ref name="pmid16169070">{{cite journal | vauthors = Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE | title = A human protein-protein interaction network: a resource for annotating the proteome | journal = Cell | volume = 122 | issue = 6 | pages = 957–68 | date = Sep 2005 | pmid = 16169070 | doi = 10.1016/j.cell.2005.08.029 }}</ref> and [[FAM135B|FAM134B]].<ref>{{Cite journal|last=Khaminets|first=Aliaksandr|last2=Heinrich|first2=Theresa|last3=Mari|first3=Muriel|last4=Grumati|first4=Paolo|last5=Huebner|first5=Antje K.|last6=Akutsu|first6=Masato|last7=Liebmann|first7=Lutz|last8=Stolz|first8=Alexandra|last9=Nietzsche|first9=Sandor|date=2015-06-18|title=Regulation of endoplasmic reticulum turnover by selective autophagy|url=http://www.nature.com/nature/journal/v522/n7556/abs/nature14498.html|journal=Nature|language=en|volume=522|issue=7556|pages=354–358|doi=10.1038/nature14498|issn=0028-0836}}</ref> | ||
{{ | |||
| | |||
| | |||
}} | |||
==References== | == References == | ||
{{reflist | {{reflist}} | ||
==Further reading== | |||
== Further reading == | |||
{{refbegin | 2}} | {{refbegin | 2}} | ||
* {{cite journal | vauthors = Rohwer A, Kittstein W, Marks F, Gschwendt M | title = Cloning, expression and characterization of an A6-related protein | journal = European Journal of Biochemistry / FEBS | volume = 263 | issue = 2 | pages = 518–25 | date = Jul 1999 | pmid = 10406962 | doi = 10.1046/j.1432-1327.1999.00537.x }} | |||
* {{cite journal | vauthors = Sagiv Y, Legesse-Miller A, Porat A, Elazar Z | title = GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28 | journal = The EMBO Journal | volume = 19 | issue = 7 | pages = 1494–504 | date = Apr 2000 | pmid = 10747018 | pmc = 310219 | doi = 10.1093/emboj/19.7.1494 }} | |||
*{{cite journal | * {{cite journal | vauthors = Hartley JL, Temple GF, Brasch MA | title = DNA cloning using in vitro site-specific recombination | journal = Genome Research | volume = 10 | issue = 11 | pages = 1788–95 | date = Nov 2000 | pmid = 11076863 | pmc = 310948 | doi = 10.1101/gr.143000 }} | ||
*{{cite journal | * {{cite journal | vauthors = Okazaki N, Yan J, Yuasa S, Ueno T, Kominami E, Masuho Y, Koga H, Muramatsu M | title = Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation | journal = Brain Research. Molecular Brain Research | volume = 85 | issue = 1-2 | pages = 1–12 | date = Dec 2000 | pmid = 11146101 | doi = 10.1016/S0169-328X(00)00218-7 }} | ||
*{{cite journal | * {{cite journal | vauthors = Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S | title = Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing | journal = EMBO Reports | volume = 1 | issue = 3 | pages = 287–92 | date = Sep 2000 | pmid = 11256614 | pmc = 1083732 | doi = 10.1093/embo-reports/kvd058 }} | ||
*{{cite journal | * {{cite journal | vauthors = Tanida I, Tanida-Miyake E, Nishitani T, Komatsu M, Yamazaki H, Ueno T, Kominami E | title = Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs | journal = Biochemical and Biophysical Research Communications | volume = 292 | issue = 1 | pages = 256–62 | date = Mar 2002 | pmid = 11890701 | doi = 10.1006/bbrc.2002.6645 }} | ||
*{{cite journal | * {{cite journal | vauthors = Scherz-Shouval R, Sagiv Y, Shorer H, Elazar Z | title = The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A | journal = The Journal of Biological Chemistry | volume = 278 | issue = 16 | pages = 14053–8 | date = Apr 2003 | pmid = 12473658 | doi = 10.1074/jbc.M212108200 }} | ||
*{{cite journal | * {{cite journal | vauthors = Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A | title = From ORFeome to biology: a functional genomics pipeline | journal = Genome Research | volume = 14 | issue = 10B | pages = 2136–44 | date = Oct 2004 | pmid = 15489336 | pmc = 528930 | doi = 10.1101/gr.2576704 }} | ||
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }} | |||
*{{cite journal | * {{cite journal | vauthors = Sou YS, Tanida I, Komatsu M, Ueno T, Kominami E | title = Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16 | journal = The Journal of Biological Chemistry | volume = 281 | issue = 6 | pages = 3017–24 | date = Feb 2006 | pmid = 16303767 | doi = 10.1074/jbc.M505888200 }} | ||
*{{cite journal | * {{cite journal | vauthors = Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S | title = The LIFEdb database in 2006 | journal = Nucleic Acids Research | volume = 34 | issue = Database issue | pages = D415-8 | date = Jan 2006 | pmid = 16381901 | pmc = 1347501 | doi = 10.1093/nar/gkj139 }} | ||
* {{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }} | |||
*{{cite journal | |||
*{{cite journal | |||
*{{cite journal | |||
*{{cite journal | |||
}} | |||
{{refend}} | {{refend}} | ||
{{ | {{PDB Gallery|geneid=11345}} | ||
{{ | |||
{{gene-16-stub}} |
Latest revision as of 08:35, 31 August 2017
VALUE_ERROR (nil) | |||||||
---|---|---|---|---|---|---|---|
Identifiers | |||||||
Aliases | |||||||
External IDs | GeneCards: [1] | ||||||
Orthologs | |||||||
Species | Human | Mouse | |||||
Entrez |
|
| |||||
Ensembl |
|
| |||||
UniProt |
|
| |||||
RefSeq (mRNA) |
|
| |||||
RefSeq (protein) |
|
| |||||
Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a | |||||
Wikidata | |||||||
|
Gamma-aminobutyric acid receptor-associated protein-like 2 is a protein that in humans is encoded by the GABARAPL2 gene.[1][2]
Interactions
GABARAPL2 has been shown to interact with ULK1,[3] ATG4B,[4][5] and FAM134B.[6]
References
- ↑ Xin Y, Yu L, Chen Z, Zheng L, Fu Q, Jiang J, Zhang P, Gong R, Zhao S (Jun 2001). "Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein". Genomics. 74 (3): 408–13. doi:10.1006/geno.2001.6555. PMID 11414770.
- ↑ "Entrez Gene: GABARAPL2 GABA(A) receptor-associated protein-like 2".
- ↑ Okazaki N, Yan J, Yuasa S, Ueno T, Kominami E, Masuho Y, Koga H, Muramatsu M (Dec 2000). "Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation". Brain Research. Molecular Brain Research. 85 (1–2): 1–12. doi:10.1016/S0169-328X(00)00218-7. PMID 11146101.
- ↑ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
- ↑ Stelzl U, Worm U, Lalowski M, Haenig C, Brembeck FH, Goehler H, Stroedicke M, Zenkner M, Schoenherr A, Koeppen S, Timm J, Mintzlaff S, Abraham C, Bock N, Kietzmann S, Goedde A, Toksöz E, Droege A, Krobitsch S, Korn B, Birchmeier W, Lehrach H, Wanker EE (Sep 2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.
- ↑ Khaminets, Aliaksandr; Heinrich, Theresa; Mari, Muriel; Grumati, Paolo; Huebner, Antje K.; Akutsu, Masato; Liebmann, Lutz; Stolz, Alexandra; Nietzsche, Sandor (2015-06-18). "Regulation of endoplasmic reticulum turnover by selective autophagy". Nature. 522 (7556): 354–358. doi:10.1038/nature14498. ISSN 0028-0836.
Further reading
- Rohwer A, Kittstein W, Marks F, Gschwendt M (Jul 1999). "Cloning, expression and characterization of an A6-related protein". European Journal of Biochemistry / FEBS. 263 (2): 518–25. doi:10.1046/j.1432-1327.1999.00537.x. PMID 10406962.
- Sagiv Y, Legesse-Miller A, Porat A, Elazar Z (Apr 2000). "GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28". The EMBO Journal. 19 (7): 1494–504. doi:10.1093/emboj/19.7.1494. PMC 310219. PMID 10747018.
- Hartley JL, Temple GF, Brasch MA (Nov 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Okazaki N, Yan J, Yuasa S, Ueno T, Kominami E, Masuho Y, Koga H, Muramatsu M (Dec 2000). "Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation". Brain Research. Molecular Brain Research. 85 (1–2): 1–12. doi:10.1016/S0169-328X(00)00218-7. PMID 11146101.
- Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
- Tanida I, Tanida-Miyake E, Nishitani T, Komatsu M, Yamazaki H, Ueno T, Kominami E (Mar 2002). "Murine Apg12p has a substrate preference for murine Apg7p over three Apg8p homologs". Biochemical and Biophysical Research Communications. 292 (1): 256–62. doi:10.1006/bbrc.2002.6645. PMID 11890701.
- Scherz-Shouval R, Sagiv Y, Shorer H, Elazar Z (Apr 2003). "The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A". The Journal of Biological Chemistry. 278 (16): 14053–8. doi:10.1074/jbc.M212108200. PMID 12473658.
- Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (Oct 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Sou YS, Tanida I, Komatsu M, Ueno T, Kominami E (Feb 2006). "Phosphatidylserine in addition to phosphatidylethanolamine is an in vitro target of the mammalian Atg8 modifiers, LC3, GABARAP, and GATE-16". The Journal of Biological Chemistry. 281 (6): 3017–24. doi:10.1074/jbc.M505888200. PMID 16303767.
- Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (Jan 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Molecular Systems Biology. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it. |