FXR2: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Fragile X mental retardation syndrome-related protein 2''' is a [[protein]] that in humans is encoded by the ''FXR2'' [[gene]].<ref name="pmid7489725">{{cite journal | vauthors = Zhang Y, O'Connor JP, Siomi MC, Srinivasan S, Dutra A, Nussbaum RL, Dreyfuss G | title = The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2 | journal = The EMBO Journal | volume = 14 | issue = 21 | pages = 5358–66 | date = Nov 1995 | pmid = 7489725 | pmc = 394645 | doi =  }}</ref><ref name="pmid9259278">{{cite journal | vauthors = Tamanini F, Willemsen R, van Unen L, Bontekoe C, Galjaard H, Oostra BA, Hoogeveen AT | title = Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis | journal = Human Molecular Genetics | volume = 6 | issue = 8 | pages = 1315–22 | date = Aug 1997 | pmid = 9259278 | pmc =  | doi = 10.1093/hmg/6.8.1315 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: FXR2 fragile X mental retardation, autosomal homolog 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9513| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
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<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Fragile X mental retardation, autosomal homolog 2
| HGNCid = 4024
| Symbol = FXR2
| AltSymbols =; FMR1L2
| OMIM = 605339
| ECnumber = 
| Homologene = 21014
| MGIid = 1346074
| GeneAtlas_image1 = PBB_GE_FXR2_35265_at_tn.png
| GeneAtlas_image2 = PBB_GE_FXR2_203172_at_tn.png
| Function = {{GNF_GO|id=GO:0003723 |text = RNA binding}}
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005842 |text = cytosolic large ribosomal subunit (sensu Eukaryota)}}
| Process =
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9513
    | Hs_Ensembl = ENSG00000129245
    | Hs_RefseqProtein = NP_004851
    | Hs_RefseqmRNA = NM_004860
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 7435272
    | Hs_GenLoc_end = 7458885
    | Hs_Uniprot = P51116
    | Mm_EntrezGene = 23879
    | Mm_Ensembl = ENSMUSG00000018765
    | Mm_RefseqmRNA = XM_001006584
    | Mm_RefseqProtein = XP_001006584
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 69449166
    | Mm_GenLoc_end = 69469492
    | Mm_Uniprot = Q6P5B5
  }}
}}
'''Fragile X mental retardation, autosomal homolog 2''', also known as '''FXR2''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: FXR2 fragile X mental retardation, autosomal homolog 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9513| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
The protein encoded by this gene is an RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.<ref name="entrez" />
{{PBB_Summary
| section_title =
| summary_text = The protein encoded by this gene is an RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.<ref name="entrez">{{cite web | title = Entrez Gene: FXR2 fragile X mental retardation, autosomal homolog 2| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9513| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
FXR2 has been shown to [[Protein-protein interaction|interact]] with:
{{div col|colwidth=20em}}
* [[CYFIP2]],<ref name = pmid11438699>{{cite journal | vauthors = Schenck A, Bardoni B, Moro A, Bagni C, Mandel JL | title = A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 98 | issue = 15 | pages = 8844–9 | date = Jul 2001 | pmid = 11438699 | pmc = 37523 | doi = 10.1073/pnas.151231598 }}</ref>
* [[FMR1]],<ref name = pmid7489725/><ref name = pmid8668200/><ref name = pmid10567518>{{cite journal | vauthors = Ceman S, Brown V, Warren ST | title = Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex | journal = Molecular and Cellular Biology | volume = 19 | issue = 12 | pages = 7925–32 | date = Dec 1999 | pmid = 10567518 | pmc = 84877 | doi =  10.1128/mcb.19.12.7925}}</ref>
* [[FXR1]],<ref name = pmid7489725 /><ref name = pmid8668200>{{cite journal | vauthors = Siomi MC, Zhang Y, Siomi H, Dreyfuss G | title = Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them | journal = Molecular and Cellular Biology | volume = 16 | issue = 7 | pages = 3825–32 | date = Jul 1996 | pmid = 8668200 | pmc = 231379 | doi =  10.1128/mcb.16.7.3825}}</ref>  and
* [[Leucine carboxyl methyltransferase 1 | LCMT1]].<ref name = pmid16189514>{{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network|authorlink30=Huda Zoghbi | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}</ref>
{{Div col end}}
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Siomi MC, Zhang Y, Siomi H, Dreyfuss G | title = Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them | journal = Molecular and Cellular Biology | volume = 16 | issue = 7 | pages = 3825–32 | date = Jul 1996 | pmid = 8668200 | pmc = 231379 | doi =  10.1128/mcb.16.7.3825}}
| citations =
* {{cite journal | vauthors = Joseph DR | title = The rat androgen-binding protein (ABP/SHBG) gene contains triplet repeats similar to unstable triplets: evidence that the ABP/SHBG and the fragile X-related 2 genes overlap | journal = Steroids | volume = 63 | issue = 1 | pages = 2–4 | date = Jan 1998 | pmid = 9437788 | doi = 10.1016/S0039-128X(97)00087-1 }}
*{{cite journal  | author=Zhang Y, O'Connor JP, Siomi MC, ''et al.'' |title=The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. |journal=EMBO J. |volume=14 |issue= 21 |pages= 5358-66 |year= 1996 |pmid= 7489725 |doi=  }}
* {{cite journal | vauthors = Tamanini F, Bontekoe C, Bakker CE, van Unen L, Anar B, Willemsen R, Yoshida M, Galjaard H, Oostra BA, Hoogeveen AT | title = Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations | journal = Human Molecular Genetics | volume = 8 | issue = 5 | pages = 863–9 | date = May 1999 | pmid = 10196376 | doi = 10.1093/hmg/8.5.863 }}
*{{cite journal | author=Siomi MC, Zhang Y, Siomi H, Dreyfuss G |title=Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3825-32 |year= 1996 |pmid= 8668200 |doi=  }}
* {{cite journal | vauthors = Bardoni B, Schenck A, Mandel JL | title = A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein | journal = Human Molecular Genetics | volume = 8 | issue = 13 | pages = 2557–66 | date = Dec 1999 | pmid = 10556305 | doi = 10.1093/hmg/8.13.2557 }}
*{{cite journal  | author=Tamanini F, Willemsen R, van Unen L, ''et al.'' |title=Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis. |journal=Hum. Mol. Genet. |volume=6 |issue= 8 |pages= 1315-22 |year= 1997 |pmid= 9259278 |doi=  }}
* {{cite journal | vauthors = Ceman S, Brown V, Warren ST | title = Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex | journal = Molecular and Cellular Biology | volume = 19 | issue = 12 | pages = 7925–32 | date = Dec 1999 | pmid = 10567518 | pmc = 84877 | doi =  10.1128/mcb.19.12.7925}}
*{{cite journal | author=Joseph DR |title=The rat androgen-binding protein (ABP/SHBG) gene contains triplet repeats similar to unstable triplets: evidence that the ABP/SHBG and the fragile X-related 2 genes overlap. |journal=Steroids |volume=63 |issue= 1 |pages= 2-4 |year= 1998 |pmid= 9437788 |doi= }}
* {{cite journal | vauthors = Cousin P, Billotte J, Chaubert P, Shaw P | title = Physical map of 17p13 and the genes adjacent to p53 | journal = Genomics | volume = 63 | issue = 1 | pages = 60–8 | date = Jan 2000 | pmid = 10662545 | doi = 10.1006/geno.1999.6062 }}
*{{cite journal | author=Tamanini F, Bontekoe C, Bakker CE, ''et al.'' |title=Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations. |journal=Hum. Mol. Genet. |volume=8 |issue= 5 |pages= 863-9 |year= 1999 |pmid= 10196376 |doi= }}
* {{cite journal | vauthors = Tamanini F, Kirkpatrick LL, Schonkeren J, van Unen L, Bontekoe C, Bakker C, Nelson DL, Galjaard H, Oostra BA, Hoogeveen AT | title = The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins | journal = Human Molecular Genetics | volume = 9 | issue = 10 | pages = 1487–93 | date = Jun 2000 | pmid = 10888599 | doi = 10.1093/hmg/9.10.1487 }}
*{{cite journal | author=Bardoni B, Schenck A, Mandel JL |title=A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein. |journal=Hum. Mol. Genet. |volume=8 |issue= 13 |pages= 2557-66 |year= 2000 |pmid= 10556305 |doi= }}
* {{cite journal | vauthors = Schenck A, Bardoni B, Moro A, Bagni C, Mandel JL | title = A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 98 | issue = 15 | pages = 8844–9 | date = Jul 2001 | pmid = 11438699 | pmc = 37523 | doi = 10.1073/pnas.151231598 }}
*{{cite journal | author=Ceman S, Brown V, Warren ST |title=Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex. |journal=Mol. Cell. Biol. |volume=19 |issue= 12 |pages= 7925-32 |year= 2000 |pmid= 10567518 |doi=  }}
* {{cite journal | vauthors = Brill LM, Salomon AR, Ficarro SB, Mukherji M, Stettler-Gill M, Peters EC | title = Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry | journal = Analytical Chemistry | volume = 76 | issue = 10 | pages = 2763–72 | date = May 2004 | pmid = 15144186 | doi = 10.1021/ac035352d }}
*{{cite journal | author=Cousin P, Billotte J, Chaubert P, Shaw P |title=Physical map of 17p13 and the genes adjacent to p53. |journal=Genomics |volume=63 |issue= 1 |pages= 60-8 |year= 2000 |pmid= 10662545 |doi= 10.1006/geno.1999.6062 }}
* {{cite journal | vauthors = Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, Zhang H, Zha XM, Polakiewicz RD, Comb MJ | title = Immunoaffinity profiling of tyrosine phosphorylation in cancer cells | journal = Nature Biotechnology | volume = 23 | issue = 1 | pages = 94–101 | date = Jan 2005 | pmid = 15592455 | doi = 10.1038/nbt1046 }}
*{{cite journal | author=Tamanini F, Kirkpatrick LL, Schonkeren J, ''et al.'' |title=The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins. |journal=Hum. Mol. Genet. |volume=9 |issue= 10 |pages= 1487-93 |year= 2000 |pmid= 10888599 |doi= }}
* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = Oct 2005 | pmid = 16189514 | doi = 10.1038/nature04209 }}
*{{cite journal | author=Schenck A, Bardoni B, Moro A, ''et al.'' |title=A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=98 |issue= 15 |pages= 8844-9 |year= 2001 |pmid= 11438699 |doi= 10.1073/pnas.151231598 }}
* {{cite journal | vauthors = Lim J, Hao T, Shaw C, Patel AJ, Szabó G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barabási AL, Vidal M, Zoghbi HY | title = A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration | journal = Cell | volume = 125 | issue = 4 | pages = 801–14 | date = May 2006 | pmid = 16713569 | doi = 10.1016/j.cell.2006.03.032 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = Nov 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Brill LM, Salomon AR, Ficarro SB, ''et al.'' |title=Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. |journal=Anal. Chem. |volume=76 |issue= 10 |pages= 2763-72 |year= 2004 |pmid= 15144186 |doi= 10.1021/ac035352d }}
* {{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rush J, Moritz A, Lee KA, ''et al.'' |title=Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. |journal=Nat. Biotechnol. |volume=23 |issue= 1 |pages= 94-101 |year= 2005 |pmid= 15592455 |doi= 10.1038/nbt1046 }}
*{{cite journal | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal | author=Lim J, Hao T, Shaw C, ''et al.'' |title=A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. |journal=Cell |volume=125 |issue= 4 |pages= 801-14 |year= 2006 |pmid= 16713569 |doi= 10.1016/j.cell.2006.03.032 }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, ''in vivo'', and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
}}
{{refend}}
{{refend}}


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Latest revision as of 02:12, 27 October 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Fragile X mental retardation syndrome-related protein 2 is a protein that in humans is encoded by the FXR2 gene.[1][2][3]

Function

The protein encoded by this gene is an RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. This encoded protein may self-associate or interact with FMRP and FXR1. It may have a role in the development of fragile X mental retardation syndrome.[3]

Interactions

FXR2 has been shown to interact with:

References

  1. ↑ 1.0 1.1 1.2 Zhang Y, O'Connor JP, Siomi MC, Srinivasan S, Dutra A, Nussbaum RL, Dreyfuss G (Nov 1995). "The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2". The EMBO Journal. 14 (21): 5358–66. PMC 394645. PMID 7489725.
  2. ↑ Tamanini F, Willemsen R, van Unen L, Bontekoe C, Galjaard H, Oostra BA, Hoogeveen AT (Aug 1997). "Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis". Human Molecular Genetics. 6 (8): 1315–22. doi:10.1093/hmg/6.8.1315. PMID 9259278.
  3. ↑ 3.0 3.1 "Entrez Gene: FXR2 fragile X mental retardation, autosomal homolog 2".
  4. ↑ Schenck A, Bardoni B, Moro A, Bagni C, Mandel JL (Jul 2001). "A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P". Proceedings of the National Academy of Sciences of the United States of America. 98 (15): 8844–9. doi:10.1073/pnas.151231598. PMC 37523. PMID 11438699.
  5. ↑ 5.0 5.1 Siomi MC, Zhang Y, Siomi H, Dreyfuss G (Jul 1996). "Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them". Molecular and Cellular Biology. 16 (7): 3825–32. doi:10.1128/mcb.16.7.3825. PMC 231379. PMID 8668200.
  6. ↑ Ceman S, Brown V, Warren ST (Dec 1999). "Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex". Molecular and Cellular Biology. 19 (12): 7925–32. doi:10.1128/mcb.19.12.7925. PMC 84877. PMID 10567518.
  7. ↑ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.

Further reading


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