USP36: Difference between revisions

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{{Infobox_gene}}
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'''Ubiquitin-specific protease 36''' is an [[enzyme]] that in humans is encoded by the ''USP36'' [[gene]].
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<ref name="pmid12838346">{{cite journal |vauthors=Puente XS, Sanchez LM, Overall CM, Lopez-Otin C | title = Human and mouse proteases: a comparative genomic approach | journal = Nat Rev Genet | volume = 4 | issue = 7 | pages = 544–558 |date=Jul 2003 | pmid = 12838346 | pmc =  | doi = 10.1038/nrg1111 }}</ref>
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<ref name="entrez">{{cite web | title = Entrez Gene: USP36 ubiquitin specific peptidase 36| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57602| accessdate = }}</ref>
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{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Ubiquitin specific peptidase 36
| HGNCid = 20062
| Symbol = USP36
| AltSymbols =; DUB1
| OMIM = 
| ECnumber = 
| Homologene = 11828
| MGIid = 1919594
| GeneAtlas_image1 = PBB_GE_USP36_220370_s_at_tn.png
| Function = {{GNF_GO|id=GO:0004221 |text = ubiquitin thiolesterase activity}}
| Component =  
| Process = {{GNF_GO|id=GO:0006511 |text = ubiquitin-dependent protein catabolic process}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 57602
    | Hs_Ensembl = ENSG00000055483
    | Hs_RefseqProtein = NP_079366
    | Hs_RefseqmRNA = NM_025090
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 17
    | Hs_GenLoc_start = 74295065
    | Hs_GenLoc_end = 74348482
    | Hs_Uniprot = Q9P275
    | Mm_EntrezGene = 72344
    | Mm_Ensembl = ENSMUSG00000033909
    | Mm_RefseqmRNA = XM_126772
    | Mm_RefseqProtein = XP_126772
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 117922712
    | Mm_GenLoc_end = 118106321
    | Mm_Uniprot = 
  }}
}}
'''Ubiquitin specific peptidase 36''', also known as '''USP36''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: USP36 ubiquitin specific peptidase 36| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=57602| accessdate = }}</ref>


This gene encodes a member of the ubiquitin-specific protease family of proteases that is a [[deubiquitinating enzyme]] (DUB) with His and Cys domains. This protein is located in the [[nucleoli]] and deubuquitinate [[nucleophosmin]] and [[fibrillarin]]<ref name="pmid19208757">{{cite journal |vauthors=Endo A, Matsumoto M, Inada T, Yamamoto A, Nakayama KI, Kitamura N, Komada M | title = Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36. | journal = J Cell Sci | volume =  122| issue =  Pt 5| pages = 678–86 |date=Mar 2009 | pmid = 19208757 | pmc =  | doi = 10.1242/jcs.044461 }}
</ref>
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Puente XS, Sánchez LM, Overall CM, López-Otín C |title=Human and mouse proteases: a comparative genomic approach. |journal=Nat. Rev. Genet. |volume=4 |issue= 7 |pages= 544-58 |year= 2003 |pmid= 12838346 |doi= 10.1038/nrg1111 }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–174 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  | author=Suzuki Y |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–156 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |name-list-format=vanc| author2=Yoshitomo-Nakagawa K  | author3=Maruyama K  | display-authors=3  | last4=Suyama  | first4=A  | last5=Sugano  | first5=S }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | author=Nagase T |title=Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro |journal=DNA Res. |volume=7 |issue= 2 |pages= 143–150 |year= 2000 |pmid= 10819331 |doi=10.1093/dnares/7.2.143  |name-list-format=vanc| author2=Kikuno R  | author3=Ishikawa K  | display-authors=3  | last4=Hirosawa  | first4=M  | last5=Ohara  | first5=O }}
*{{cite journal  | author=Nagase T, Kikuno R, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=7 |issue= 2 |pages= 143-50 |year= 2000 |pmid= 10819331 |doi=  }}
*{{cite journal  | author=Scherl A |title=Functional proteomic analysis of human nucleolus |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–4109 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 | pmc=133617  |name-list-format=vanc| author2=Couté Y  | author3=Déon C  | display-authors=3  | last4=Callé  | first4=A  | last5=Kindbeiter  | first5=K  | last6=Sanchez  | first6=JC  | last7=Greco  | first7=A  | last8=Hochstrasser  | first8=D  | last9=Diaz  | first9=JJ }}
*{{cite journal  | author=Scherl A, Couté Y, Déon C, ''et al.'' |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100-9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–16903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–45 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Quesada V |title=Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases |journal=Biochem. Biophys. Res. Commun. |volume=314 |issue= 1 |pages= 54–62 |year= 2004 |pmid= 14715245 |doi=10.1016/j.bbrc.2003.12.050  |name-list-format=vanc| author2=Díaz-Perales A  | author3=Gutiérrez-Fernández A  | display-authors=3  | last4=Garabaya  | first4=Cecilia  | last5=Cal  | first5=Santiago  | last6=López-Otı́n  | first6=Carlos }}
*{{cite journal  | author=Quesada V, Díaz-Perales A, Gutiérrez-Fernández A, ''et al.'' |title=Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. |journal=Biochem. Biophys. Res. Commun. |volume=314 |issue= 1 |pages= 54-62 |year= 2004 |pmid= 14715245 |doi=  }}
*{{cite journal  | author=Kim MS |title=A novel cysteine protease HeLa DUB-1 responsible for cleaving the ubiquitin in human ovarian cancer cells |journal=Int. J. Oncol. |volume=25 |issue= 2 |pages= 373–9 |year= 2005 |pmid= 15254734 |doi= 10.3892/ijo.25.2.373|name-list-format=vanc| author2=Yoo KJ  | author3=Kang I  | display-authors=3  | last4=Chung  | first4=HM  | last5=Baek  | first5=KH }}
*{{cite journal  | author=Kim MS, Yoo KJ, Kang I, ''et al.'' |title=A novel cysteine protease HeLa DUB-1 responsible for cleaving the ubiquitin in human ovarian cancer cells. |journal=Int. J. Oncol. |volume=25 |issue= 2 |pages= 373-9 |year= 2005 |pmid= 15254734 |doi=  }}
*{{cite journal  | author=Andersen JS |title=Nucleolar proteome dynamics |journal=Nature |volume=433 |issue= 7021 |pages= 77–83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 |name-list-format=vanc| author2=Lam YW  | author3=Leung AK  | display-authors=3  | last4=Ong  | first4=Shao-En  | last5=Lyon  | first5=Carol E.  | last6=Lamond  | first6=Angus I.  | last7=Mann  | first7=Matthias }}
*{{cite journal  | author=Andersen JS, Lam YW, Leung AK, ''et al.'' |title=Nucleolar proteome dynamics. |journal=Nature |volume=433 |issue= 7021 |pages= 77-83 |year= 2005 |pmid= 15635413 |doi= 10.1038/nature03207 }}
*{{cite journal  | author=Kim MS |title=Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated |journal=Biochem. Biophys. Res. Commun. |volume=330 |issue= 3 |pages= 797–804 |year= 2005 |pmid= 15809067 |doi= 10.1016/j.bbrc.2005.03.051 |name-list-format=vanc| author2=Kim YK  | author3=Kim YS  | display-authors=3  | last4=Seong  | first4=Minu  | last5=Choi  | first5=Joong-Kook  | last6=Baek  | first6=Kwang-Hyun }}
*{{cite journal  | author=Kim MS, Kim YK, Kim YS, ''et al.'' |title=Deubiquitinating enzyme USP36 contains the PEST motif and is polyubiquitinated. |journal=Biochem. Biophys. Res. Commun. |volume=330 |issue= 3 |pages= 797-804 |year= 2005 |pmid= 15809067 |doi= 10.1016/j.bbrc.2005.03.051 }}
*{{cite journal  | author=Nousiainen M |title=Phosphoproteome analysis of the human mitotic spindle |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–5396 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 | pmc=1459365  |name-list-format=vanc| author2=Silljé HH  | author3=Sauer G  | display-authors=3  | last4=Nigg  | first4=EA  | last5=Körner  | first5=R }}
*{{cite journal  | author=Nousiainen M, Silljé HH, Sauer G, ''et al.'' |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391-6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 }}
*{{cite journal  | author=Olsen JV |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–648 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |name-list-format=vanc| author2=Blagoev B  | author3=Gnad F  | display-authors=3  | last4=Macek  | first4=Boris  | last5=Kumar  | first5=Chanchal  | last6=Mortensen  | first6=Peter  | last7=Mann  | first7=Matthias }}
*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
}}
}}
{{refend}}
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Latest revision as of 04:29, 11 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ubiquitin-specific protease 36 is an enzyme that in humans is encoded by the USP36 gene. [1] [2]

This gene encodes a member of the ubiquitin-specific protease family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the nucleoli and deubuquitinate nucleophosmin and fibrillarin[3]


References

  1. Puente XS, Sanchez LM, Overall CM, Lopez-Otin C (Jul 2003). "Human and mouse proteases: a comparative genomic approach". Nat Rev Genet. 4 (7): 544–558. doi:10.1038/nrg1111. PMID 12838346.
  2. "Entrez Gene: USP36 ubiquitin specific peptidase 36".
  3. Endo A, Matsumoto M, Inada T, Yamamoto A, Nakayama KI, Kitamura N, Komada M (Mar 2009). "Nucleolar structure and function are regulated by the deubiquitylating enzyme USP36". J Cell Sci. 122 (Pt 5): 678–86. doi:10.1242/jcs.044461. PMID 19208757.

Further reading