EMP3: Difference between revisions

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{{Infobox_gene}}
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'''Epithelial membrane protein 3''' is a [[protein]] that in humans is encoded by the ''EMP3'' [[gene]].<ref name="pmid8996089">{{cite journal | vauthors = Ben-Porath I, Benvenisty N | title = Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins | journal = Gene | volume = 183 | issue = 1–2 | pages = 69–75 |date=Feb 1997 | pmid = 8996089 | pmc =  | doi =10.1016/S0378-1119(96)00475-1 }}</ref><ref name="pmid10331954">{{cite journal | vauthors = Liehr T, Kuhlenbaumer G, Wulf P, Taylor V, Suter U, Van Broeckhoven C, Lupski JR, Claussen U, Rautenstrauss B | title = Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3 | journal = Genomics | volume = 58 | issue = 1 | pages = 106–8 |date=Jul 1999 | pmid = 10331954 | pmc =  | doi = 10.1006/geno.1999.5803 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: EMP3 epithelial membrane protein 3| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2014| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Epithelial membrane protein 3
| HGNCid = 3335
| Symbol = EMP3
| AltSymbols =; YMP
| OMIM = 602335
| ECnumber =
| Homologene = 1090
| MGIid = 1098729
  | GeneAtlas_image1 = PBB_GE_EMP3_203729_at_tn.png
| Function =
  | Component = {{GNF_GO|id=GO:0005624 |text = membrane fraction}} {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
| Process = {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0008219 |text = cell death}} {{GNF_GO|id=GO:0008285 |text = negative regulation of cell proliferation}} {{GNF_GO|id=GO:0016049 |text = cell growth}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 2014
    | Hs_Ensembl = ENSG00000142227
    | Hs_RefseqProtein = NP_001416
    | Hs_RefseqmRNA = NM_001425
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 19
    | Hs_GenLoc_start = 53520441
    | Hs_GenLoc_end = 53525623
    | Hs_Uniprot = P54852
    | Mm_EntrezGene = 13732
    | Mm_Ensembl = ENSMUSG00000040212
    | Mm_RefseqmRNA = NM_010129
    | Mm_RefseqProtein = NP_034259
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 7
    | Mm_GenLoc_start = 45786106
    | Mm_GenLoc_end = 45789446
    | Mm_Uniprot = Q3UIF8
  }}
}}
'''Epithelial membrane protein 3''', also known as '''EMP3''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: EMP3 epithelial membrane protein 3| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2014| accessdate = }}</ref>
 
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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin |30em}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Lobsiger CS, Magyar JP, Taylor V, ''et al.'' |title=Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1. |journal=Genomics |volume=36 |issue= 3 |pages= 379-87 |year= 1997 |pmid= 8884260 |doi=  }}
*{{cite journal  | vauthors=Lobsiger CS, Magyar JP, Taylor V |title=Identification and characterization of a cDNA and the structural gene encoding the mouse epithelial membrane protein-1 |journal=Genomics |volume=36 |issue= 3 |pages= 379–87 |year= 1997 |pmid= 8884260 |doi=10.1006/geno.1996.0482 |display-authors=etal}}
*{{cite journal  | author=Taylor V, Suter U |title=Epithelial membrane protein-2 and epithelial membrane protein-3: two novel members of the peripheral myelin protein 22 gene family. |journal=Gene |volume=175 |issue= 1-2 |pages= 115-20 |year= 1996 |pmid= 8917086 |doi= }}
*{{cite journal  | vauthors=Taylor V, Suter U |title=Epithelial membrane protein-2 and epithelial membrane protein-3: two novel members of the peripheral myelin protein 22 gene family |journal=Gene |volume=175 |issue= 1–2 |pages= 115–20 |year= 1996 |pmid= 8917086 |doi=10.1016/0378-1119(96)00134-5 }}
*{{cite journal  | author=Ben-Porath I, Benvenisty N |title=Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins. |journal=Gene |volume=183 |issue= 1-2 |pages= 69-75 |year= 1997 |pmid= 8996089 |doi= }}
*{{cite journal  | vauthors=Bolin LM, McNeil T, Lucian LA |title=HNMP-1: a novel hematopoietic and neural membrane protein differentially regulated in neural development and injury |journal=J. Neurosci. |volume=17 |issue= 14 |pages= 5493–502 |year= 1997 |pmid= 9204931 |doi=  |display-authors=etal}}
*{{cite journal  | author=Bolin LM, McNeil T, Lucian LA, ''et al.'' |title=HNMP-1: a novel hematopoietic and neural membrane protein differentially regulated in neural development and injury. |journal=J. Neurosci. |volume=17 |issue= 14 |pages= 5493-502 |year= 1997 |pmid= 9204931 |doi=  }}
*{{cite journal  | vauthors=Yus-Najera E, Santana-Castro I, Villarroel A |title=The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels |journal=J. Biol. Chem. |volume=277 |issue= 32 |pages= 28545–53 |year= 2002 |pmid= 12032157 |doi= 10.1074/jbc.M204130200 }}
*{{cite journal  | author=Liehr T, Kuhlenbäumer G, Wulf P, ''et al.'' |title=Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3. |journal=Genomics |volume=58 |issue= 1 |pages= 106-8 |year= 1999 |pmid= 10331954 |doi= 10.1006/geno.1999.5803 }}
*{{cite journal  | vauthors=Wilson HL, Wilson SA, Surprenant A, North RA |title=Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus |journal=J. Biol. Chem. |volume=277 |issue= 37 |pages= 34017–23 |year= 2002 |pmid= 12107182 |doi= 10.1074/jbc.M205120200 }}
*{{cite journal  | author=Yus-Najera E, Santana-Castro I, Villarroel A |title=The identification and characterization of a noncontinuous calmodulin-binding site in noninactivating voltage-dependent KCNQ potassium channels. |journal=J. Biol. Chem. |volume=277 |issue= 32 |pages= 28545-53 |year= 2002 |pmid= 12032157 |doi= 10.1074/jbc.M204130200 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Wilson HL, Wilson SA, Surprenant A, North RA |title=Epithelial membrane proteins induce membrane blebbing and interact with the P2X7 receptor C terminus. |journal=J. Biol. Chem. |volume=277 |issue= 37 |pages= 34017-23 |year= 2002 |pmid= 12107182 |doi= 10.1074/jbc.M205120200 }}
*{{cite journal  | vauthors=Schwake M, Jentsch TJ, Friedrich T |title=A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly |journal=EMBO Rep. |volume=4 |issue= 1 |pages= 76–81 |year= 2003 |pmid= 12524525 |doi= 10.1038/sj.embor.embor715 | pmc=1315815 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Yus-Nájera E, Muñoz A, Salvador N |title=Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation |journal=Neuroscience |volume=120 |issue= 2 |pages= 353–64 |year= 2003 |pmid= 12890507 |doi=10.1016/S0306-4522(03)00321-X |display-authors=etal}}
*{{cite journal  | author=Schwake M, Jentsch TJ, Friedrich T |title=A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly. |journal=EMBO Rep. |volume=4 |issue= 1 |pages= 76-81 |year= 2003 |pmid= 12524525 |doi= 10.1038/sj.embor.embor715 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Yus-Nájera E, Muñoz A, Salvador N, ''et al.'' |title=Localization of KCNQ5 in the normal and epileptic human temporal neocortex and hippocampal formation. |journal=Neuroscience |volume=120 |issue= 2 |pages= 353-64 |year= 2003 |pmid= 12890507 |doi=  }}
*{{cite journal  | vauthors=Nielsen K, Heegaard S, Vorum H |title=Altered expression of CLC, DSG3, EMP3, S100A2, and SLPI in corneal epithelium from keratoconus patients |journal=Cornea |volume=24 |issue= 6 |pages= 661–8 |year= 2005 |pmid= 16015083 |doi=10.1097/01.ico.0000153556.59407.69 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Li KK, Pang JC, Chung NY |title=EMP3 overexpression is associated with oligodendroglial tumors retaining chromosome arms 1p and 19q |journal=Int. J. Cancer |volume=120 |issue= 4 |pages= 947–50 |year= 2007 |pmid= 17187361 |doi= 10.1002/ijc.22415 |display-authors=etal}}
*{{cite journal  | author=Nielsen K, Heegaard S, Vorum H, ''et al.'' |title=Altered expression of CLC, DSG3, EMP3, S100A2, and SLPI in corneal epithelium from keratoconus patients. |journal=Cornea |volume=24 |issue= 6 |pages= 661-8 |year= 2005 |pmid= 16015083 |doi=  }}
*{{cite journal  | vauthors=Kunitz A, Wolter M, van den Boom J |title=DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas |journal=Brain Pathol. |volume=17 |issue= 4 |pages= 363–70 |year= 2007 |pmid= 17610521 |doi= 10.1111/j.1750-3639.2007.00083.x |display-authors=etal}}
*{{cite journal  | author=Li KK, Pang JC, Chung NY, ''et al.'' |title=EMP3 overexpression is associated with oligodendroglial tumors retaining chromosome arms 1p and 19q. |journal=Int. J. Cancer |volume=120 |issue= 4 |pages= 947-50 |year= 2007 |pmid= 17187361 |doi= 10.1002/ijc.22415 }}
*{{cite journal  | author=Kunitz A, Wolter M, van den Boom J, ''et al.'' |title=DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas. |journal=Brain Pathol. |volume=17 |issue= 4 |pages= 363-70 |year= 2007 |pmid= 17610521 |doi= 10.1111/j.1750-3639.2007.00083.x }}
}}
}}
{{refend}}
{{refend}}


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Revision as of 00:29, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Epithelial membrane protein 3 is a protein that in humans is encoded by the EMP3 gene.[1][2][3]


References

  1. ↑ Ben-Porath I, Benvenisty N (Feb 1997). "Characterization of a tumor-associated gene, a member of a novel family of genes encoding membrane glycoproteins". Gene. 183 (1–2): 69–75. doi:10.1016/S0378-1119(96)00475-1. PMID 8996089.
  2. ↑ Liehr T, Kuhlenbaumer G, Wulf P, Taylor V, Suter U, Van Broeckhoven C, Lupski JR, Claussen U, Rautenstrauss B (Jul 1999). "Regional localization of the human epithelial membrane protein genes 1, 2, and 3 (EMP1, EMP2, EMP3) to 12p12.3, 16p13.2, and 19q13.3". Genomics. 58 (1): 106–8. doi:10.1006/geno.1999.5803. PMID 10331954.
  3. ↑ "Entrez Gene: EMP3 epithelial membrane protein 3".

Further reading



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