RAB3D: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Ras-related protein Rab-3D''' is a [[protein]] that in humans is encoded by the ''RAB3D'' [[gene]].<ref name="pmid10023084">{{cite journal |vauthors=Nishio H, Suda T, Sawada K, Miyamoto T, Koike T, Yamaguchi Y | title = Molecular cloning of cDNA encoding human Rab3D whose expression is upregulated with myeloid differentiation | journal = Biochim Biophys Acta | volume = 1444 | issue = 2 | pages = 283–90 |date=Mar 1999 | pmid = 10023084 | pmc =  | doi 10.1016/s0167-4781(98)00279-6}}</ref><ref name="pmid10072586">{{cite journal |vauthors=Chen XN, Shi ZY, Korenberg JR, Sehgal A | title = Assignment of the GOV (Glioblastoma overexpressed) gene to human chromosome band 19p13.2 by fluorescence in situ hybridization | journal = Cytogenet Cell Genet | volume = 83 | issue = 3–4 | pages = 230–1 |date=Mar 1999 | pmid = 10072586 | pmc =  | doi =10.1159/000015187 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RAB3D RAB3D, member RAS oncogene family| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9545| accessdate = }}</ref>
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{{GNF_Protein_box
| image = PBB_Protein_RAB3D_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 2gf9.
| PDB = {{PDB2|2gf9}}
| Name = RAB3D, member RAS oncogene family
| HGNCid = 9779
| Symbol = RAB3D
| AltSymbols =; D2-2; GOV; RAB16; RAD3D
| OMIM = 604350
| ECnumber =
| Homologene = 20902
| MGIid = 97844
| GeneAtlas_image1 = PBB_GE_RAB3D_208466_at_tn.png
  | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003924 |text = GTPase activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
  | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0042588 |text = zymogen granule}}
| Process = {{GNF_GO|id=GO:0007264 |text = small GTPase mediated signal transduction}} {{GNF_GO|id=GO:0007516 |text = hemocyte development}} {{GNF_GO|id=GO:0015031 |text = protein transport}} {{GNF_GO|id=GO:0017157 |text = regulation of exocytosis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9545
    | Hs_Ensembl = ENSG00000105514
    | Hs_RefseqProtein = NP_004274
    | Hs_RefseqmRNA = NM_004283
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 19
    | Hs_GenLoc_start = 11296094
    | Hs_GenLoc_end = 11311321
    | Hs_Uniprot = O95716
    | Mm_EntrezGene = 19340
    | Mm_Ensembl = ENSMUSG00000019066
    | Mm_RefseqmRNA = NM_031874
    | Mm_RefseqProtein = NP_114080
    | Mm_GenLoc_db =   
    | Mm_GenLoc_chr = 9
    | Mm_GenLoc_start = 21657912
    | Mm_GenLoc_end = 21668523
    | Mm_Uniprot = Q543Q4
  }}
}}
'''RAB3D, member RAS oncogene family''', also known as '''RAB3D''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RAB3D RAB3D, member RAS oncogene family| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9545| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Brondyk WH, McKiernan CJ, Fortner KA, ''et al.'' |title=Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A. |journal=Mol. Cell. Biol. |volume=15 |issue= 3 |pages= 1137-43 |year= 1995 |pmid= 7532276 |doi=  }}
*{{cite journal  | author=Brondyk WH |title=Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A |journal=Mol. Cell. Biol. |volume=15 |issue= 3 |pages= 1137–43 |year= 1995 |pmid= 7532276 |doi= | pmc=230335  |name-list-format=vanc| author2=McKiernan CJ  | author3=Fortner KA  | display-authors=3  | last4=Stabila  | first4=P  | last5=Holz  | first5=RW  | last6=MacAra  | first6=IG }}
*{{cite journal  | author=Sehgal A, Keener C, Boynton AL, ''et al.'' |title=Isolation and characterization of a novel gene from human glioblastoma multiforme tumor tissue. |journal=Int. J. Cancer |volume=71 |issue= 4 |pages= 565-72 |year= 1997 |pmid= 9178809 |doi=  }}
*{{cite journal  | author=Sehgal A |title=Isolation and characterization of a novel gene from human glioblastoma multiforme tumor tissue |journal=Int. J. Cancer |volume=71 |issue= 4 |pages= 565–72 |year= 1997 |pmid= 9178809 |doi=10.1002/(SICI)1097-0215(19970516)71:4<565::AID-IJC10>3.0.CO;2-B  |name-list-format=vanc| author2=Keener C  | author3=Boynton AL  | display-authors=3  | last4=Young  | first4=Ronald F.  | last5=Vermeulen  | first5=Sandra S.  | last6=Yonemura  | first6=Kenneth S.  | last7=Kohler  | first7=Erik P.  | last8=Aldape  | first8=Hector C.  | last9=Simrell  | first9=Charles R. }}
*{{cite journal  | author=Raffaniello RD, Raufman JP |title=Cytosolic RAB3D is associated with RAB escort protein (REP), not RAB-GDP dissociation inhibitor (GDI), in dispersed chief cells from guinea pig stomach. |journal=J. Cell. Biochem. |volume=72 |issue= 4 |pages= 540-8 |year= 1999 |pmid= 10022613 |doi= }}
*{{cite journal  |vauthors=Raffaniello RD, Raufman JP |title=Cytosolic RAB3D is associated with RAB escort protein (REP), not RAB-GDP dissociation inhibitor (GDI), in dispersed chief cells from guinea pig stomach |journal=J. Cell. Biochem. |volume=72 |issue= 4 |pages= 540–8 |year= 1999 |pmid= 10022613 |doi=10.1002/(SICI)1097-4644(19990315)72:4<540::AID-JCB9>3.0.CO;2-D }}
*{{cite journal  | author=Nishio H, Suda T, Sawada K, ''et al.'' |title=Molecular cloning of cDNA encoding human Rab3D whose expression is upregulated with myeloid differentiation. |journal=Biochim. Biophys. Acta |volume=1444 |issue= 2 |pages= 283-90 |year= 1999 |pmid= 10023084 |doi=  }}
*{{cite journal  |vauthors=Cartel NJ, Wang J, Post M |title=Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt |journal=Biochem. J. |volume=363 |issue= Pt 1 |pages= 19–28 |year= 2002 |pmid= 11903042 |doi=10.1042/0264-6021:3630019  | pmc=1222446 }}
*{{cite journal  | author=Chen XN, Shi ZY, Korenberg JR, Sehgal A |title=Assignment of the GOV (Glioblastoma overexpressed) gene to human chromosome band 19p13.2 by fluorescence in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=83 |issue= 3-4 |pages= 230-1 |year= 1999 |pmid= 10072586 |doi= }}
*{{cite journal  | author=Riedel D |title=Rab3D Is Not Required for Exocrine Exocytosis but for Maintenance of Normally Sized Secretory Granules |journal=Mol. Cell. Biol. |volume=22 |issue= 18 |pages= 6487–97 |year= 2002 |pmid= 12192047 |doi=10.1128/MCB.22.18.6487-6497.2002  | pmc=135623  |name-list-format=vanc| author2=Antonin W  | author3=Fernandez-Chacon R  | display-authors=3  | last4=Alvarez De Toledo  | first4=G.  | last5=Jo  | first5=T.  | last6=Geppert  | first6=M.  | last7=Valentijn  | first7=J. A.  | last8=Valentijn  | first8=K.  | last9=Jamieson  | first9=J. D. }}
*{{cite journal  | author=Cartel NJ, Wang J, Post M |title=Platelet-derived growth factor-BB-mediated glycosaminoglycan synthesis is transduced through Akt. |journal=Biochem. J. |volume=363 |issue= Pt 1 |pages= 19-28 |year= 2002 |pmid= 11903042 |doi=  }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Riedel D, Antonin W, Fernandez-Chacon R, ''et al.'' |title=Rab3D is not required for exocrine exocytosis but for maintenance of normally sized secretory granules. |journal=Mol. Cell. Biol. |volume=22 |issue= 18 |pages= 6487-97 |year= 2002 |pmid= 12192047 |doi=  }}
*{{cite journal  | author=Fukuda M |title=Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2 |journal=J. Biol. Chem. |volume=278 |issue= 17 |pages= 15373–80 |year= 2003 |pmid= 12578829 |doi= 10.1074/jbc.M212341200 }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Nguyen D |title=Rab3D redistribution and function in rat parotid acini |journal=J. Cell. Physiol. |volume=197 |issue= 3 |pages= 400–8 |year= 2003 |pmid= 14566969 |doi= 10.1002/jcp.10373 |name-list-format=vanc| author2=Jones A  | author3=Ojakian GK  | display-authors=3  | last4=Raffaniello  | first4=Robert D. }}
*{{cite journal  | author=Fukuda M |title=Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2. |journal=J. Biol. Chem. |volume=278 |issue= 17 |pages= 15373-80 |year= 2003 |pmid= 12578829 |doi= 10.1074/jbc.M212341200 }}
*{{cite journal  | author=Matsumoto M |title=Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 22 |pages= 8313–8 |year= 2004 |pmid= 15159548 |doi= 10.1073/pnas.0306709101 | pmc=420391  |name-list-format=vanc| author2=Miki T  | author3=Shibasaki T  | display-authors=3  | last4=Kawaguchi  | first4=M  | last5=Shinozaki  | first5=H  | last6=Nio  | first6=J  | last7=Saraya  | first7=A  | last8=Koseki  | first8=H  | last9=Miyazaki  | first9=M }}
*{{cite journal  | author=Nguyen D, Jones A, Ojakian GK, ''et al.'' |title=Rab3D redistribution and function in rat parotid acini. |journal=J. Cell. Physiol. |volume=197 |issue= 3 |pages= 400-8 |year= 2003 |pmid= 14566969 |doi= 10.1002/jcp.10373 }}
*{{cite journal  |vauthors=Knop M, Aareskjold E, Bode G, Gerke V |title=Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells |journal=EMBO J. |volume=23 |issue= 15 |pages= 2982–92 |year= 2005 |pmid= 15257287 |doi= 10.1038/sj.emboj.7600319 | pmc=514934 }}
*{{cite journal  | author=Matsumoto M, Miki T, Shibasaki T, ''et al.'' |title=Noc2 is essential in normal regulation of exocytosis in endocrine and exocrine cells. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 22 |pages= 8313-8 |year= 2004 |pmid= 15159548 |doi= 10.1073/pnas.0306709101 }}
*{{cite journal  | author=Gerhard DS |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928  |name-list-format=vanc| author2=Wagner L  | author3=Feingold EA  | display-authors=3  | last4=Shenmen  | first4=CM  | last5=Grouse  | first5=LH  | last6=Schuler  | first6=G  | last7=Klein  | first7=SL  | last8=Old  | first8=S  | last9=Rasooly  | first9=R }}
*{{cite journal  | author=Knop M, Aareskjold E, Bode G, Gerke V |title=Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells. |journal=EMBO J. |volume=23 |issue= 15 |pages= 2982-92 |year= 2005 |pmid= 15257287 |doi= 10.1038/sj.emboj.7600319 }}
*{{cite journal  | author=Rual JF |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |name-list-format=vanc| author2=Venkatesan K  | author3=Hao T  | display-authors=3  | last4=Hirozane-Kishikawa  | first4=Tomoko  | last5=Dricot  | first5=Amélie  | last6=Li  | first6=Ning  | last7=Berriz  | first7=Gabriel F.  | last8=Gibbons  | first8=Francis D.  | last9=Dreze  | first9=Matija }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=9545}}
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Revision as of 08:47, 10 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Ras-related protein Rab-3D is a protein that in humans is encoded by the RAB3D gene.[1][2][3]


References

  1. Nishio H, Suda T, Sawada K, Miyamoto T, Koike T, Yamaguchi Y (Mar 1999). "Molecular cloning of cDNA encoding human Rab3D whose expression is upregulated with myeloid differentiation". Biochim Biophys Acta. 1444 (2): 283–90. doi:10.1016/s0167-4781(98)00279-6. PMID 10023084.
  2. Chen XN, Shi ZY, Korenberg JR, Sehgal A (Mar 1999). "Assignment of the GOV (Glioblastoma overexpressed) gene to human chromosome band 19p13.2 by fluorescence in situ hybridization". Cytogenet Cell Genet. 83 (3–4): 230–1. doi:10.1159/000015187. PMID 10072586.
  3. "Entrez Gene: RAB3D RAB3D, member RAS oncogene family".

Further reading