TUBB1: Difference between revisions

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Latest revision as of 12:26, 15 September 2017

TUBB1 is a gene that codes for the protein Tubulin beta-1 chain in humans.^[1]

References

↑ "Entrez Gene: TUBB1 tubulin, beta 1".

Watts NR, Sackett DL, Ward RD, et al. (2000). "HIV-1 Rev Depolymerizes Microtubules to Form Stable Bilayered Rings". J. Cell Biol. 150 (2): 349–60. doi:10.1083/jcb.150.2.349. PMC 2180222. PMID 10908577.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.
Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Chen D, Wang M, Zhou S, Zhou Q (2004). "HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim". EMBO J. 21 (24): 6801–10. doi:10.1093/emboj/cdf683. PMC 139103. PMID 12486001.
Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID 12665801.
Yanagida M, Hayano T, Yamauchi Y, et al. (2004). "Human fibrillarin forms a sub-complex with splicing factor 2-associated p32, protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes". J. Biol. Chem. 279 (3): 1607–14. doi:10.1074/jbc.M305604200. PMID 14583623.
Dou Z, Ding X, Zereshki A, et al. (2004). "TTK kinase is essential for the centrosomal localization of TACC2". FEBS Lett. 572 (1–3): 51–6. doi:10.1016/j.febslet.2004.06.092. PMID 15304323.
Schulze H, Korpal M, Bergmeier W, et al. (2005). "Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions". Blood. 104 (13): 3949–57. doi:10.1182/blood-2004-03-1179. PMID 15315966.
Campbell GR, Pasquier E, Watkins J, et al. (2005). "The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis". J. Biol. Chem. 279 (46): 48197–204. doi:10.1074/jbc.M406195200. PMID 15331610.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
de Mareuil J, Carre M, Barbier P, et al. (2006). "HIV-1 Tat protein enhances Microtubule polymerization". Retrovirology. 2: 5. doi:10.1186/1742-4690-2-5. PMC 549075. PMID 15691386.
Giacca M (2006). "HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?". Retrovirology. 2: 7. doi:10.1186/1742-4690-2-7. PMC 549042. PMID 15698476.
Freson K, De Vos R, Wittevrongel C, et al. (2005). "The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure". Blood. 106 (7): 2356–62. doi:10.1182/blood-2005-02-0723. PMID 15956286.
Mesquita B, Veiga I, Pereira D, et al. (2006). "No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin". BMC Cancer. 5: 101. doi:10.1186/1471-2407-5-101. PMC 1199587. PMID 16095531.
Coiras M, Camafeita E, Ureña T, et al. (2006). "Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression". Proteomics. 6 Suppl 1: S63–73. doi:10.1002/pmic.200500437. PMID 16526095.
Navarro-Núñez L, Lozano ML, Rivera J, et al. (2007). "The association of the beta1-tubulin Q43P polymorphism with intracerebral hemorrhage in men". Haematologica. 92 (4): 513–8. doi:10.3324/haematol.10689. PMID 17488662.

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by expanding it.

[entrez-1] "Entrez Gene: TUBB1 tubulin, beta 1".

[1]

@@ Line 1: / Line 1: @@
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+{{Underlinked|date=June 2016}}
-{{PBB_Controls
+{{Infobox_gene}}
-| update_page = yes
+'''TUBB1''' is a [[gene]] that codes for the [[protein]] '''Tubulin beta-1 chain''' in humans.<ref name="entrez">{{cite web | title = Entrez Gene: TUBB1 tubulin, beta 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81027| accessdate = }}</ref>
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-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = Tubulin, beta 1
- | HGNCid = 16257
- | Symbol = TUBB1
- | AltSymbols =; dJ543J19.4
- | OMIM =
- | ECnumber =
- | Homologene = 69474
- | MGIid = 107814
- | GeneAtlas_image1 = PBB_GE_TUBB1_208601_s_at_tn.png
- | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003924 |text = GTPase activity}} {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0005525 |text = GTP binding}}
- | Component = {{GNF_GO|id=GO:0005874 |text = microtubule}} {{GNF_GO|id=GO:0043234 |text = protein complex}}
- | Process = {{GNF_GO|id=GO:0007018 |text = microtubule-based movement}} {{GNF_GO|id=GO:0051258 |text = protein polymerization}}
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 81027
-    | Hs_Ensembl = ENSG00000101162
-    | Hs_RefseqProtein = NP_110400
-    | Hs_RefseqmRNA = NM_030773
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 20
-    | Hs_GenLoc_start = 57027704
-    | Hs_GenLoc_end = 57035104
-    | Hs_Uniprot = Q9H4B7
-    | Mm_EntrezGene = 545486
-    | Mm_Ensembl =
-    | Mm_RefseqmRNA = XM_619851
-    | Mm_RefseqProtein = XP_619851
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr =
-    | Mm_GenLoc_start =
-    | Mm_GenLoc_end =
-    | Mm_Uniprot =
-  }}
-}}
-'''Tubulin, beta 1''', also known as '''TUBB1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TUBB1 tubulin, beta 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=81027| accessdate = }}</ref>
 <!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
 {{PBB_Summary
@@ Line 55: / Line 9: @@
 ==References==
-{{reflist|2}}
+{{reflist}}
 ==Further reading==
 {{refbegin | 2}}
 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Watts NR, Sackett DL, Ward RD, ''et al.'' |title=HIV-1 rev depolymerizes microtubules to form stable bilayered rings. |journal=J. Cell Biol. |volume=150 |issue= 2 |pages= 349-60 |year= 2000 |pmid= 10908577 |doi=  }}
+*{{cite journal   |vauthors=Watts NR, Sackett DL, Ward RD, etal |title=HIV-1 Rev Depolymerizes Microtubules to Form Stable Bilayered Rings |journal=J. Cell Biol. |volume=150 |issue= 2 |pages= 349–60 |year= 2000 |pmid= 10908577 |doi=10.1083/jcb.150.2.349  | pmc=2180222  }}
-*{{cite journal  | author=Deloukas P, Matthews LH, Ashurst J, ''et al.'' |title=The DNA sequence and comparative analysis of human chromosome 20. |journal=Nature |volume=414 |issue= 6866 |pages= 865-71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
+*{{cite journal   |vauthors=Deloukas P, Matthews LH, Ashurst J, etal |title=The DNA sequence and comparative analysis of human chromosome 20 |journal=Nature |volume=414 |issue= 6866 |pages= 865–71 |year= 2002 |pmid= 11780052 |doi= 10.1038/414865a }}
-*{{cite journal  | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi=  }}
+*{{cite journal   |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 }}
-*{{cite journal  | author=Chen D, Wang M, Zhou S, Zhou Q |title=HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim. |journal=EMBO J. |volume=21 |issue= 24 |pages= 6801-10 |year= 2004 |pmid= 12486001 |doi=  }}
+*{{cite journal  | vauthors=Chen D, Wang M, Zhou S, Zhou Q |title=HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim |journal=EMBO J. |volume=21 |issue= 24 |pages= 6801–10 |year= 2004 |pmid= 12486001 |doi=10.1093/emboj/cdf683  | pmc=139103  }}
-*{{cite journal  | author=Gevaert K, Goethals M, Martens L, ''et al.'' |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566-9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
+*{{cite journal   |vauthors=Gevaert K, Goethals M, Martens L, etal |title=Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides |journal=Nat. Biotechnol. |volume=21 |issue= 5 |pages= 566–9 |year= 2004 |pmid= 12665801 |doi= 10.1038/nbt810 }}
-*{{cite journal  | author=Yanagida M, Hayano T, Yamauchi Y, ''et al.'' |title=Human fibrillarin forms a sub-complex with splicing factor 2-associated p32, protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes. |journal=J. Biol. Chem. |volume=279 |issue= 3 |pages= 1607-14 |year= 2004 |pmid= 14583623 |doi= 10.1074/jbc.M305604200 }}
+*{{cite journal   |vauthors=Yanagida M, Hayano T, Yamauchi Y, etal |title=Human fibrillarin forms a sub-complex with splicing factor 2-associated p32, protein arginine methyltransferases, and tubulins alpha 3 and beta 1 that is independent of its association with preribosomal ribonucleoprotein complexes |journal=J. Biol. Chem. |volume=279 |issue= 3 |pages= 1607–14 |year= 2004 |pmid= 14583623 |doi= 10.1074/jbc.M305604200 }}
-*{{cite journal  | author=Dou Z, Ding X, Zereshki A, ''et al.'' |title=TTK kinase is essential for the centrosomal localization of TACC2. |journal=FEBS Lett. |volume=572 |issue= 1-3 |pages= 51-6 |year= 2004 |pmid= 15304323 |doi= 10.1016/j.febslet.2004.06.092 }}
+*{{cite journal   |vauthors=Dou Z, Ding X, Zereshki A, etal |title=TTK kinase is essential for the centrosomal localization of TACC2 |journal=FEBS Lett. |volume=572 |issue= 1–3 |pages= 51–6 |year= 2004 |pmid= 15304323 |doi= 10.1016/j.febslet.2004.06.092 }}
-*{{cite journal  | author=Schulze H, Korpal M, Bergmeier W, ''et al.'' |title=Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions. |journal=Blood |volume=104 |issue= 13 |pages= 3949-57 |year= 2005 |pmid= 15315966 |doi= 10.1182/blood-2004-03-1179 }}
+*{{cite journal   |vauthors=Schulze H, Korpal M, Bergmeier W, etal |title=Interactions between the megakaryocyte/platelet-specific beta1 tubulin and the secretory leukocyte protease inhibitor SLPI suggest a role for regulated proteolysis in platelet functions |journal=Blood |volume=104 |issue= 13 |pages= 3949–57 |year= 2005 |pmid= 15315966 |doi= 10.1182/blood-2004-03-1179 }}
-*{{cite journal  | author=Campbell GR, Pasquier E, Watkins J, ''et al.'' |title=The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis. |journal=J. Biol. Chem. |volume=279 |issue= 46 |pages= 48197-204 |year= 2005 |pmid= 15331610 |doi= 10.1074/jbc.M406195200 }}
+*{{cite journal   |vauthors=Campbell GR, Pasquier E, Watkins J, etal |title=The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis |journal=J. Biol. Chem. |volume=279 |issue= 46 |pages= 48197–204 |year= 2005 |pmid= 15331610 |doi= 10.1074/jbc.M406195200 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=de Mareuil J, Carre M, Barbier P, ''et al.'' |title=HIV-1 Tat protein enhances microtubule polymerization. |journal=Retrovirology |volume=2 |issue=  |pages= 5 |year= 2006 |pmid= 15691386 |doi= 10.1186/1742-4690-2-5 }}
+*{{cite journal   |vauthors=de Mareuil J, Carre M, Barbier P, etal |title=HIV-1 Tat protein enhances Microtubule polymerization |journal=Retrovirology |volume=2 |issue=  |pages= 5 |year= 2006 |pmid= 15691386 |doi= 10.1186/1742-4690-2-5  | pmc=549075 }}
-*{{cite journal  | author=Giacca M |title=HIV-1 Tat, apoptosis and the mitochondria: a tubulin link? |journal=Retrovirology |volume=2 |issue=  |pages= 7 |year= 2006 |pmid= 15698476 |doi= 10.1186/1742-4690-2-7 }}
+*{{cite journal  | author=Giacca M |title=HIV-1 Tat, apoptosis and the mitochondria: a tubulin link? |journal=Retrovirology |volume=2 |issue=  |pages= 7 |year= 2006 |pmid= 15698476 |doi= 10.1186/1742-4690-2-7  | pmc=549042 }}
-*{{cite journal  | author=Freson K, De Vos R, Wittevrongel C, ''et al.'' |title=The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure. |journal=Blood |volume=106 |issue= 7 |pages= 2356-62 |year= 2005 |pmid= 15956286 |doi= 10.1182/blood-2005-02-0723 }}
+*{{cite journal   |vauthors=Freson K, De Vos R, Wittevrongel C, etal |title=The TUBB1 Q43P functional polymorphism reduces the risk of cardiovascular disease in men by modulating platelet function and structure |journal=Blood |volume=106 |issue= 7 |pages= 2356–62 |year= 2005 |pmid= 15956286 |doi= 10.1182/blood-2005-02-0723 }}
-*{{cite journal  | author=Mesquita B, Veiga I, Pereira D, ''et al.'' |title=No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin. |journal=BMC Cancer |volume=5 |issue=  |pages= 101 |year= 2006 |pmid= 16095531 |doi= 10.1186/1471-2407-5-101 }}
+*{{cite journal   |vauthors=Mesquita B, Veiga I, Pereira D, etal |title=No significant role for beta tubulin mutations and mismatch repair defects in ovarian cancer resistance to paclitaxel/cisplatin |journal=BMC Cancer |volume=5|pages= 101 |year= 2006 |pmid= 16095531 |doi= 10.1186/1471-2407-5-101  | pmc=1199587 }}
-*{{cite journal  | author=Coiras M, Camafeita E, Ureña T, ''et al.'' |title=Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression. |journal=Proteomics |volume=6 Suppl 1 |issue=  |pages= S63-73 |year=  |pmid= 16526095 |doi= 10.1002/pmic.200500437 }}
+*{{cite journal   |vauthors=Coiras M, Camafeita E, Ureña T, etal |title=Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression |journal=Proteomics |volume=6 Suppl 1 |issue=  |pages= S63–73 |year=  2006|pmid= 16526095 |doi= 10.1002/pmic.200500437 }}
-*{{cite journal  | author=Navarro-Núñez L, Lozano ML, Rivera J, ''et al.'' |title=The association of the beta1-tubulin Q43P polymorphism with intracerebral hemorrhage in men. |journal=Haematologica |volume=92 |issue= 4 |pages= 513-8 |year= 2007 |pmid= 17488662 |doi=  }}
+*{{cite journal   |vauthors=Navarro-Núñez L, Lozano ML, Rivera J, etal |title=The association of the beta1-tubulin Q43P polymorphism with intracerebral hemorrhage in men |journal=Haematologica |volume=92 |issue= 4 |pages= 513–8 |year= 2007 |pmid= 17488662 |doi=10.3324/haematol.10689  }}
 }}
 {{refend}}
-{{protein-stub}}
+<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
-{{WikiDoc Sources}}
+{{PBB_Controls
+| update_page = yes
+| require_manual_inspection = no
+| update_protein_box = yes
+| update_summary = yes
+| update_citations = yes
+}}
+{{gene-20-stub}}

TUBB1: Difference between revisions

Latest revision as of 12:26, 15 September 2017

References

Further reading

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