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{{Infobox_gene}}
{{PBB_Controls
'''Clathrin interactor 1''' ('''CLINT1'''), also known as '''EPSIN4''', is a [[protein]] which in humans is encoded by the ''CLINT1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CLINT1 clathrin interactor 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9685| accessdate = }}</ref><ref name="pmid12213833">{{cite journal | vauthors = Wasiak S, Legendre-Guillemin V, Puertollano R, Blondeau F, Girard M, de Heuvel E, Boismenu D, Bell AW, Bonifacino JS, McPherson PS | title = Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics | journal = J. Cell Biol. | volume = 158 | issue = 5 | pages = 855–62 |date=September 2002 | pmid = 12213833 | pmc = 2173151 | doi = 10.1083/jcb.200205078 | url = | issn = }}</ref><ref name="pmid12429846">{{cite journal | vauthors = Kalthoff C, Groos S, Kohl R, Mahrhold S, Ungewickell EJ | title = Clint: a novel clathrin-binding ENTH-domain protein at the Golgi | journal = Mol. Biol. Cell | volume = 13 | issue = 11 | pages = 4060–73 |date=November 2002 | pmid = 12429846 | pmc = 133614 | doi = 10.1091/mbc.E02-03-0171 | url = | issn = }}</ref>
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== Function ==
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The CLINT1 protein binds to the terminal domain of the [[CLTC|clathrin heavy chain]] and stimulates [[clathrin]] cage vesicle assembly. Clathrin coated vesicles enable neurotransmitter receptors and other proteins to be endocytosed or taken up across neuronal membranes and across the membranes of other types of cells. This enables a turnover of neuroreceptors or other proteins to be maintained and thus the numbers of receptors can be fine tuned.<ref name="pmid12213833"/>
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== Clinical significance ==
The ''CLINT1'' gene has been shown to be involved in the genetic aetiology of schizophrenia in four studies <ref name="pmid15793701">{{cite journal | vauthors = Pimm J, McQuillin A, Thirumalai S, Lawrence J, Quested D, Bass N, Lamb G, Moorey H, Datta SR, Kalsi G, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Curtis D, Gurling H | title = The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia | journal = Am. J. Hum. Genet. | volume = 76 | issue = 5 | pages = 902–7 |date=May 2005 | pmid = 15793701 | pmc = 1199380 | doi = 10.1086/430095 | url = | issn = }}</ref><ref name="pmid17070672">{{cite journal | vauthors = Gurling H, Pimm J, McQuillin A | title = Replication of genetic association studies between markers at the Epsin 4 gene locus and schizophrenia in two Han Chinese samples | journal = Schizophr. Res. | volume = 89 | issue = 1-3 | pages = 357–9 |date=January 2007 | pmid = 17070672 | doi = 10.1016/j.schres.2006.08.024 | url = | issn = }}</ref><ref name="pmid16402136">{{cite journal | vauthors = Tang RQ, Zhao XZ, Shi YY, Tang W, Gu NF, Feng GY, Xing YL, Zhu SM, Sang H, Liang PJ, He L | title = Family-based association study of Epsin 4 and Schizophrenia | journal = Mol. Psychiatry | volume = 11 | issue = 4 | pages = 395–9 |date=April 2006 | pmid = 16402136 | doi = 10.1038/sj.mp.4001780 | url = | issn = }}</ref><ref name="pmid16616458">{{cite journal | vauthors = Liou YJ, Lai IC, Wang YC, Bai YM, Lin CC, Lin CY, Chen TT, Chen JY | title = Genetic analysis of the human ENTH (Epsin 4) gene and schizophrenia | journal = Schizophr. Res. | volume = 84 | issue = 2-3 | pages = 236–43 |date=June 2006 | pmid = 16616458 | doi = 10.1016/j.schres.2006.02.021 | url = | issn = }}</ref><ref name="pmid18929466">{{cite journal | vauthors = Escamilla M, Lee BD, Ontiveros A, Raventos H, Nicolini H, Mendoza R, Jerez A, Munoz R, Medina R, Figueroa A, Walss-Bass C, Armas R, Contreras S, Ramirez ME, Dassori A | title = The epsin 4 gene is associated with psychotic disorders in families of Latin American origin | journal = Schizophr. Res. | volume = 106 | issue = 2-3 | pages = 253–7 |date=December 2008 | pmid = 18929466 | doi = 10.1016/j.schres.2008.09.005 | url = | issn = }}</ref> It is known that the  [[antipsychotic]] drugs [[chlorpromazine]] and [[clozapine]] stabilise clathrin coated vesicles<ref name="pmid1901801">{{cite journal | vauthors = Phonphok Y, Rosenthal KS | title = Stabilization of clathrin coated vesicles by amantadine, tromantadine and other hydrophobic amines | journal = FEBS Lett. | volume = 281 | issue = 1-2 | pages = 188–90 |date=April 1991 | pmid = 1901801 | doi = 10.1016/0014-5793(91)80390-O  | url = | issn = }}</ref><ref name="pmid10655494">{{cite journal | vauthors = Claing A, Perry SJ, Achiriloaie M, Walker JK, Albanesi JP, Lefkowitz RJ, Premont RT| title = Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 97 | issue = 3 | pages = 1119–24 |date=February 2000 | pmid = 10655494 | pmc = 15541 | doi = 10.1073/pnas.97.3.1119| url = http://www.pnas.org/cgi/pmidlookup?view=long&pmid=10655494 | issn = }}</ref> and this may be one reason why antipsychotic drugs are effective in treating delusions, auditory hallucinations and many of the other symptoms of schizophrenia.
 
==Interactions==
CLINT1 has been shown to [[Protein-protein interaction|interact]] with [[GGA2]].<ref name=pmid12213833 /><ref name=pmid12429846 />


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== References ==
{{GNF_Protein_box
{{Reflist|2}}
| image = PBB_Protein_CLINT1_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1xgw.
| PDB = {{PDB2|1xgw}}
| Name = Clathrin interactor 1
| HGNCid = 23186
| Symbol = CLINT1
| AltSymbols =; CLINT; ENTH; EPN4; EPNR; EPSINR; KIAA0171
| OMIM = 607265
| ECnumber = 
| Homologene = 6309
| MGIid = 2144243
| GeneAtlas_image1 = PBB_GE_CLINT1_201768_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_CLINT1_201769_at_tn.png
| Function = {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0008289 |text = lipid binding}}
| Component = {{GNF_GO|id=GO:0005794 |text = Golgi apparatus}}
| Process = {{GNF_GO|id=GO:0006897 |text = endocytosis}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9685
    | Hs_Ensembl = ENSG00000113282
    | Hs_RefseqProtein = NP_055481
    | Hs_RefseqmRNA = NM_014666
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 5
    | Hs_GenLoc_start = 157146500
    | Hs_GenLoc_end = 157218731
    | Hs_Uniprot = Q14677
    | Mm_EntrezGene = 216705
    | Mm_Ensembl = ENSMUSG00000006169
    | Mm_RefseqmRNA = XM_908092
    | Mm_RefseqProtein = XP_913185
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 11
    | Mm_GenLoc_start = 45727131
    | Mm_GenLoc_end = 45754046
    | Mm_Uniprot = Q3TJF5
  }}
}}
'''Clathrin interactor 1''', also known as '''CLINT1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: CLINT1 clathrin interactor 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9685| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
==External links==
{{PBB_Summary
* {{UCSC gene info|CLINT1}}
| section_title =
| summary_text =
}}


==References==
== Further reading ==
{{reflist|2}}
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Nagase T, Seki N, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=3 |issue= 1 |pages= 17-24 |year= 1996 |pmid= 8724849 |doi=  }}
*{{cite journal  | vauthors=Nagase T, Seki N, Ishikawa K |title=Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=3 |issue= 1 |pages= 17–24 |year= 1996 |pmid= 8724849 |doi=10.1093/dnares/3.1.17 |display-authors=etal}}
*{{cite journal  | author=Hoja MR, Wahlestedt C, Höög C |title=A visual intracellular classification strategy for uncharacterized human proteins. |journal=Exp. Cell Res. |volume=259 |issue= 1 |pages= 239-46 |year= 2000 |pmid= 10942595 |doi= 10.1006/excr.2000.4948 }}
*{{cite journal  | vauthors=Hoja MR, Wahlestedt C, Höög C |title=A visual intracellular classification strategy for uncharacterized human proteins. |journal=Exp. Cell Res. |volume=259 |issue= 1 |pages= 239–46 |year= 2000 |pmid= 10942595 |doi= 10.1006/excr.2000.4948 }}
*{{cite journal  | author=Wasiak S, Legendre-Guillemin V, Puertollano R, ''et al.'' |title=Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics. |journal=J. Cell Biol. |volume=158 |issue= 5 |pages= 855-62 |year= 2002 |pmid= 12213833 |doi= 10.1083/jcb.200205078 }}
*{{cite journal  | vauthors=Wasiak S, Legendre-Guillemin V, Puertollano R |title=Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics. |journal=J. Cell Biol. |volume=158 |issue= 5 |pages= 855–62 |year= 2002 |pmid= 12213833 |doi= 10.1083/jcb.200205078 | pmc=2173151 |display-authors=etal}}
*{{cite journal  | author=Kalthoff C, Groos S, Kohl R, ''et al.'' |title=Clint: a novel clathrin-binding ENTH-domain protein at the Golgi. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4060-73 |year= 2003 |pmid= 12429846 |doi= 10.1091/mbc.E02-03-0171 }}
*{{cite journal  | vauthors=Kalthoff C, Groos S, Kohl R |title=Clint: a novel clathrin-binding ENTH-domain protein at the Golgi. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4060–73 |year= 2003 |pmid= 12429846 |doi= 10.1091/mbc.E02-03-0171 | pmc=133614 |display-authors=etal}}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 |display-authors=etal}}
*{{cite journal  | author=Mills IG, Praefcke GJ, Vallis Y, ''et al.'' |title=EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking. |journal=J. Cell Biol. |volume=160 |issue= 2 |pages= 213-22 |year= 2003 |pmid= 12538641 |doi= 10.1083/jcb.200208023 }}
*{{cite journal  | vauthors=Mills IG, Praefcke GJ, Vallis Y |title=EpsinR: an AP1/clathrin interacting protein involved in vesicle trafficking. |journal=J. Cell Biol. |volume=160 |issue= 2 |pages= 213–22 |year= 2003 |pmid= 12538641 |doi= 10.1083/jcb.200208023 | pmc=2172650 |display-authors=etal}}
*{{cite journal  | author=Hirst J, Motley A, Harasaki K, ''et al.'' |title=EpsinR: an ENTH domain-containing protein that interacts with AP-1. |journal=Mol. Biol. Cell |volume=14 |issue= 2 |pages= 625-41 |year= 2003 |pmid= 12589059 |doi= 10.1091/mbc.E02-09-0552 }}
*{{cite journal  | vauthors=Hirst J, Motley A, Harasaki K |title=EpsinR: an ENTH domain-containing protein that interacts with AP-1. |journal=Mol. Biol. Cell |volume=14 |issue= 2 |pages= 625–41 |year= 2003 |pmid= 12589059 |doi= 10.1091/mbc.E02-09-0552 | pmc=149997 |display-authors=etal}}
*{{cite journal  | author=Wasiak S, Denisov AY, Han Z, ''et al.'' |title=Characterization of a gamma-adaptin ear-binding motif in enthoprotin. |journal=FEBS Lett. |volume=555 |issue= 3 |pages= 437-42 |year= 2004 |pmid= 14675752 |doi=  }}
*{{cite journal  | vauthors=Wasiak S, Denisov AY, Han Z |title=Characterization of a gamma-adaptin ear-binding motif in enthoprotin. |journal=FEBS Lett. |volume=555 |issue= 3 |pages= 437–42 |year= 2004 |pmid= 14675752 |doi=10.1016/S0014-5793(03)01299-7 |display-authors=etal}}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | vauthors=Ota T, Suzuki Y, Nishikawa T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |display-authors=etal}}
*{{cite journal  | author=Saint-Pol A, Yélamos B, Amessou M, ''et al.'' |title=Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes. |journal=Dev. Cell |volume=6 |issue= 4 |pages= 525-38 |year= 2004 |pmid= 15068792 |doi=  }}
*{{cite journal  | vauthors=Saint-Pol A, Yélamos B, Amessou M |title=Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes. |journal=Dev. Cell |volume=6 |issue= 4 |pages= 525–38 |year= 2004 |pmid= 15068792 |doi=10.1016/S1534-5807(04)00100-5 |display-authors=etal}}
*{{cite journal  | author=Jin J, Smith FD, Stark C, ''et al.'' |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436-50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 }}
*{{cite journal  | vauthors=Jin J, Smith FD, Stark C |title=Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization. |journal=Curr. Biol. |volume=14 |issue= 16 |pages= 1436–50 |year= 2004 |pmid= 15324660 |doi= 10.1016/j.cub.2004.07.051 |display-authors=etal}}
*{{cite journal  | author=Hirst J, Miller SE, Taylor MJ, ''et al.'' |title=EpsinR is an adaptor for the SNARE protein Vti1b. |journal=Mol. Biol. Cell |volume=15 |issue= 12 |pages= 5593-602 |year= 2005 |pmid= 15371541 |doi= 10.1091/mbc.E04-06-0468 }}
*{{cite journal  | vauthors=Hirst J, Miller SE, Taylor MJ |title=EpsinR is an adaptor for the SNARE protein Vti1b. |journal=Mol. Biol. Cell |volume=15 |issue= 12 |pages= 5593–602 |year= 2005 |pmid= 15371541 |doi= 10.1091/mbc.E04-06-0468 | pmc=532037 |display-authors=etal}}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 |display-authors=etal}}
*{{cite journal  | author=Pimm J, McQuillin A, Thirumalai S, ''et al.'' |title=The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia. |journal=Am. J. Hum. Genet. |volume=76 |issue= 5 |pages= 902-7 |year= 2005 |pmid= 15793701 |doi= 10.1086/430095 }}
*{{cite journal  | vauthors=Pimm J, McQuillin A, Thirumalai S |title=The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia. |journal=Am. J. Hum. Genet. |volume=76 |issue= 5 |pages= 902–7 |year= 2005 |pmid= 15793701 |doi= 10.1086/430095 | pmc=1199380 |display-authors=etal}}
*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
*{{cite journal  | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
*{{cite journal  | author=Tang RQ, Zhao XZ, Shi YY, ''et al.'' |title=Family-based association study of Epsin 4 and Schizophrenia. |journal=Mol. Psychiatry |volume=11 |issue= 4 |pages= 395-9 |year= 2006 |pmid= 16402136 |doi= 10.1038/sj.mp.4001780 }}
*{{cite journal  | vauthors=Tang RQ, Zhao XZ, Shi YY |title=Family-based association study of Epsin 4 and Schizophrenia. |journal=Mol. Psychiatry |volume=11 |issue= 4 |pages= 395–9 |year= 2006 |pmid= 16402136 |doi= 10.1038/sj.mp.4001780 |display-authors=etal}}
*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=9685}}


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Latest revision as of 09:49, 30 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Clathrin interactor 1 (CLINT1), also known as EPSIN4, is a protein which in humans is encoded by the CLINT1 gene.[1][2][3]

Function

The CLINT1 protein binds to the terminal domain of the clathrin heavy chain and stimulates clathrin cage vesicle assembly. Clathrin coated vesicles enable neurotransmitter receptors and other proteins to be endocytosed or taken up across neuronal membranes and across the membranes of other types of cells. This enables a turnover of neuroreceptors or other proteins to be maintained and thus the numbers of receptors can be fine tuned.[2]

Clinical significance

The CLINT1 gene has been shown to be involved in the genetic aetiology of schizophrenia in four studies [4][5][6][7][8] It is known that the antipsychotic drugs chlorpromazine and clozapine stabilise clathrin coated vesicles[9][10] and this may be one reason why antipsychotic drugs are effective in treating delusions, auditory hallucinations and many of the other symptoms of schizophrenia.

Interactions

CLINT1 has been shown to interact with GGA2.[2][3]

References

  1. ↑ "Entrez Gene: CLINT1 clathrin interactor 1".
  2. ↑ 2.0 2.1 2.2 Wasiak S, Legendre-Guillemin V, Puertollano R, Blondeau F, Girard M, de Heuvel E, Boismenu D, Bell AW, Bonifacino JS, McPherson PS (September 2002). "Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics". J. Cell Biol. 158 (5): 855–62. doi:10.1083/jcb.200205078. PMC 2173151. PMID 12213833.
  3. ↑ 3.0 3.1 Kalthoff C, Groos S, Kohl R, Mahrhold S, Ungewickell EJ (November 2002). "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi". Mol. Biol. Cell. 13 (11): 4060–73. doi:10.1091/mbc.E02-03-0171. PMC 133614. PMID 12429846.
  4. ↑ Pimm J, McQuillin A, Thirumalai S, Lawrence J, Quested D, Bass N, Lamb G, Moorey H, Datta SR, Kalsi G, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Curtis D, Gurling H (May 2005). "The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia". Am. J. Hum. Genet. 76 (5): 902–7. doi:10.1086/430095. PMC 1199380. PMID 15793701.
  5. ↑ Gurling H, Pimm J, McQuillin A (January 2007). "Replication of genetic association studies between markers at the Epsin 4 gene locus and schizophrenia in two Han Chinese samples". Schizophr. Res. 89 (1–3): 357–9. doi:10.1016/j.schres.2006.08.024. PMID 17070672.
  6. ↑ Tang RQ, Zhao XZ, Shi YY, Tang W, Gu NF, Feng GY, Xing YL, Zhu SM, Sang H, Liang PJ, He L (April 2006). "Family-based association study of Epsin 4 and Schizophrenia". Mol. Psychiatry. 11 (4): 395–9. doi:10.1038/sj.mp.4001780. PMID 16402136.
  7. ↑ Liou YJ, Lai IC, Wang YC, Bai YM, Lin CC, Lin CY, Chen TT, Chen JY (June 2006). "Genetic analysis of the human ENTH (Epsin 4) gene and schizophrenia". Schizophr. Res. 84 (2–3): 236–43. doi:10.1016/j.schres.2006.02.021. PMID 16616458.
  8. ↑ Escamilla M, Lee BD, Ontiveros A, Raventos H, Nicolini H, Mendoza R, Jerez A, Munoz R, Medina R, Figueroa A, Walss-Bass C, Armas R, Contreras S, Ramirez ME, Dassori A (December 2008). "The epsin 4 gene is associated with psychotic disorders in families of Latin American origin". Schizophr. Res. 106 (2–3): 253–7. doi:10.1016/j.schres.2008.09.005. PMID 18929466.
  9. ↑ Phonphok Y, Rosenthal KS (April 1991). "Stabilization of clathrin coated vesicles by amantadine, tromantadine and other hydrophobic amines". FEBS Lett. 281 (1–2): 188–90. doi:10.1016/0014-5793(91)80390-O. PMID 1901801.
  10. ↑ Claing A, Perry SJ, Achiriloaie M, Walker JK, Albanesi JP, Lefkowitz RJ, Premont RT (February 2000). "Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity". Proc. Natl. Acad. Sci. U.S.A. 97 (3): 1119–24. doi:10.1073/pnas.97.3.1119. PMC 15541. PMID 10655494.

External links

Further reading


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