T-complex 1: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +))
 
m (→‎Further reading: task, replaced: Philos. Trans. R. Soc. Lond., B, Biol. Sci. → Philos. Trans. R. Soc. Lond. B Biol. Sci. using AWB)
 
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Infobox_gene}}
{{PBB_Controls
'''T-complex protein 1 subunit alpha''' is a [[protein]] that in humans is encoded by the ''TCP1'' [[gene]].<ref name="pmid3476253">{{cite journal | vauthors = Fonatsch C, Gradl G, Ragoussis J, Ziegler A | title = Assignment of the TCP1 locus to the long arm of human chromosome 6 by in situ hybridization | journal = Cytogenet Cell Genet | volume = 45 | issue = 2 | pages = 109–12 | date = Oct 1987 | pmid = 3476253 | pmc =  | doi = 10.1159/000132439 }}</ref><ref name="pmid3653076">{{cite journal | vauthors = Willison K, Kelly A, Dudley K, Goodfellow P, Spurr N, Groves V, Gorman P, Sheer D, Trowsdale J | title = The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region | journal = EMBO J | volume = 6 | issue = 7 | pages = 1967–74 | date = Nov 1987 | pmid = 3653076 | pmc = 553584 | doi = }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: TCP1 t-complex 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6950| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = T-complex 1
| HGNCid = 11655
| Symbol = TCP1
| AltSymbols =; CCT-alpha; CCT1; CCTa; D6S230E; TCP-1-alpha
| OMIM = 186980
| ECnumber = 
| Homologene = 5656
| MGIid = 98535
| GeneAtlas_image1 = PBB_GE_TCP1_222011_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_TCP1_208778_s_at_tn.png
| GeneAtlas_image3 = PBB_GE_TCP1_222010_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0051082 |text = unfolded protein binding}}
| Component = {{GNF_GO|id=GO:0000242 |text = pericentriolar material}} {{GNF_GO|id=GO:0005720 |text = nuclear heterochromatin}} {{GNF_GO|id=GO:0005815 |text = microtubule organizing center}} {{GNF_GO|id=GO:0005829 |text = cytosol}} {{GNF_GO|id=GO:0005832 |text = chaperonin-containing T-complex}}
| Process = {{GNF_GO|id=GO:0006457 |text = protein folding}} {{GNF_GO|id=GO:0007021 |text = tubulin folding}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 6950
    | Hs_Ensembl = ENSG00000120438
    | Hs_RefseqProtein = NP_001008897
    | Hs_RefseqmRNA = NM_001008897
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 6
    | Hs_GenLoc_start = 160119520
    | Hs_GenLoc_end = 160130731
    | Hs_Uniprot = P17987
    | Mm_EntrezGene = 21454
    | Mm_Ensembl = ENSMUSG00000068039
    | Mm_RefseqmRNA = NM_013686
    | Mm_RefseqProtein = NP_038714
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 17
    | Mm_GenLoc_start = 12759413
    | Mm_GenLoc_end = 12767488
    | Mm_Uniprot = Q3TJ96
  }}
}}
'''T-complex 1''', also known as '''TCP1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: TCP1 t-complex 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6950| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.<ref name="entrez"/>
{{PBB_Summary
| section_title =
| summary_text = This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.<ref name="entrez">{{cite web | title = Entrez Gene: TCP1 t-complex 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6950| accessdate = }}</ref>
}}


==References==
== Interactions ==
{{reflist|2}}
 
==Further reading==
T-complex 1 has been shown to [[Protein-protein interaction|interact]] with [[PPP4C]]<ref name=pmid18715871>{{cite journal | vauthors = Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC | title = PP4R4/KIAA1622 Forms a Novel Stable Cytosolic Complex with Phosphoprotein Phosphatase 4 | journal = J. Biol. Chem. | volume = 283 | issue = 43 | pages = 29273–84 | date = Oct 2008 | pmid = 18715871 | pmc = 2662017 | doi = 10.1074/jbc.M803443200 }}</ref><ref name=pmid16085932>{{cite journal | vauthors = Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R | title = A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity | journal = Mol. Cell. Proteomics | volume = 4 | issue = 11 | pages = 1725–40 | date = Nov 2005 | pmid = 16085932 | doi = 10.1074/mcp.M500231-MCP200 }}</ref> and [[HDAC3]].<ref name=pmid12502735>{{cite journal | vauthors = Guenther MG, Yu J, Kao GD, Yen TJ, Lazar MA | title = Assembly of the SMRT–histone deacetylase 3 repression complex requires the TCP-1 ring complex | journal = Genes Dev. | volume = 16 | issue = 24 | pages = 3130–5 | date = Dec 2002 | pmid = 12502735 | pmc = 187500 | doi = 10.1101/gad.1037502 }}</ref> CCT also directly interacts with lectin type oxidized LDL receptor-1 (LOX-1) while its ligand oxidized low density lipoprotein (OxLDL) disassociates CCT from [[LOX-1]].<ref name=pmid24846140>{{cite journal | vauthors = Bakthavatsalam D, Soung RH, Tweardy DJ, Chiu W, Dixon RA, Woodside DG | title = Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor. | journal = FEBS Lett | volume = 588 | issue = 13 | pages = 2133–40 | date = Jun 2014 | pmid = 24846140 | pmc = 4100626| doi =  10.1016/j.febslet.2014.04.049}}</ref>
 
== References ==
{{reflist}}
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Horwich AL, Willison KR | title = Protein folding in the cell: functions of two families of molecular chaperone, hsp 60 and TF55-TCP1 | journal = Philos. Trans. R. Soc. Lond. B Biol. Sci. | volume = 339 | issue = 1289 | pages = 313–25; discussion 325–6 | year = 1993 | pmid = 8098536 | doi = 10.1098/rstb.1993.0030 }}
| citations =
* {{cite journal | vauthors = Burston SG, Clarke AR | title = Molecular chaperones: physical and mechanistic properties | journal = Essays Biochem. | volume = 29 | issue =  | pages = 125–36 | year = 1997 | pmid = 9189717 | doi =  }}
*{{cite journal | author=Horwich AL, Willison KR |title=Protein folding in the cell: functions of two families of molecular chaperone, hsp 60 and TF55-TCP1. |journal=Philos. Trans. R. Soc. Lond., B, Biol. Sci. |volume=339 |issue= 1289 |pages= 313-25; discussion 325-6 |year= 1993 |pmid= 8098536 |doi= 10.1098/rstb.1993.0030 }}
* {{cite journal | vauthors = Blanché H, Wright LG, Vergnaud G, de Gouyon B, Lauthier V, Silver LM, Dausset J, Cann HM, Spielman RS | title = Genetic mapping of three human homologues of murine t-complex genes localizes TCP10 to 6q27, 15 cM distal to TCP1 and PLG | journal = Genomics | volume = 12 | issue = 4 | pages = 826–8 | year = 1992 | pmid = 1572657 | doi = 10.1016/0888-7543(92)90317-L }}
*{{cite journal | author=Burston SG, Clarke AR |title=Molecular chaperones: physical and mechanistic properties. |journal=Essays Biochem. |volume=29 |issue=  |pages= 125-36 |year= 1997 |pmid= 9189717 |doi=  }}
* {{cite journal | vauthors = Dawson SJ, White LA | title = Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin | journal = J. Infect. | volume = 24 | issue = 3 | pages = 317–20 | year = 1992 | pmid = 1602151 | doi = 10.1016/S0163-4453(05)80037-4 }}
*{{cite journal | author=Blanché H, Wright LG, Vergnaud G, ''et al.'' |title=Genetic mapping of three human homologues of murine t-complex genes localizes TCP10 to 6q27, 15 cM distal to TCP1 and PLG. |journal=Genomics |volume=12 |issue= 4 |pages= 826-8 |year= 1992 |pmid= 1572657 |doi= }}
* {{cite journal | vauthors = Yaffe MB, Farr GW, Miklos D, Horwich AL, Sternlicht ML, Sternlicht H | title = TCP1 complex is a molecular chaperone in tubulin biogenesis | journal = Nature | volume = 358 | issue = 6383 | pages = 245–8 | year = 1992 | pmid = 1630491 | doi = 10.1038/358245a0 }}
*{{cite journal | author=Dawson SJ, White LA |title=Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin. |journal=J. Infect. |volume=24 |issue= 3 |pages= 317-20 |year= 1992 |pmid= 1602151 |doi= }}
* {{cite journal | vauthors = Lewis VA, Hynes GM, Zheng D, Saibil H, Willison K | title = T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol | journal = Nature | volume = 358 | issue = 6383 | pages = 249–52 | year = 1992 | pmid = 1630492 | doi = 10.1038/358249a0 }}
*{{cite journal | author=Yaffe MB, Farr GW, Miklos D, ''et al.'' |title=TCP1 complex is a molecular chaperone in tubulin biogenesis. |journal=Nature |volume=358 |issue= 6383 |pages= 245-8 |year= 1992 |pmid= 1630491 |doi= 10.1038/358245a0 }}
* {{cite journal | vauthors = Ursic D, Culbertson MR | title = The yeast homolog to mouse Tcp-1 affects microtubule-mediated processes | journal = Mol. Cell. Biol. | volume = 11 | issue = 5 | pages = 2629–40 | year = 1991 | pmid = 1901944 | pmc = 360032 | doi =  }}
*{{cite journal | author=Lewis VA, Hynes GM, Zheng D, ''et al.'' |title=T-complex polypeptide-1 is a subunit of a heteromeric particle in the eukaryotic cytosol. |journal=Nature |volume=358 |issue= 6383 |pages= 249-52 |year= 1992 |pmid= 1630492 |doi= 10.1038/358249a0 }}
* {{cite journal | vauthors = Kirchhoff C, Willison K | title = Nucleotide and amino-acid sequence of human testis-derived TCP1 | journal = Nucleic Acids Res. | volume = 18 | issue = 14 | pages = 4247 | year = 1990 | pmid = 2377466 | pmc = 331189 | doi = 10.1093/nar/18.14.4247 }}
*{{cite journal | author=Ursic D, Culbertson MR |title=The yeast homolog to mouse Tcp-1 affects microtubule-mediated processes. |journal=Mol. Cell. Biol. |volume=11 |issue= 5 |pages= 2629-40 |year= 1991 |pmid= 1901944 |doi=  }}
* {{cite journal | vauthors = Roobol A, Holmes FE, Hayes NV, Baines AJ, Carden MJ | title = Cytoplasmic chaperonin complexes enter neurites developing in vitro and differ in subunit composition within single cells | journal = J. Cell Sci. | volume = 108 | issue = 4 | pages = 1477–88 | year = 1995 | pmid = 7615668 | doi =  }}
*{{cite journal | author=Kirchhoff C, Willison K |title=Nucleotide and amino-acid sequence of human testis-derived TCP1. |journal=Nucleic Acids Res. |volume=18 |issue= 14 |pages= 4247 |year= 1990 |pmid= 2377466 |doi= }}
* {{cite journal | vauthors = Ashworth A | title = Two acetyl-CoA acetyltransferase genes located in the t-complex region of mouse chromosome 17 partially overlap the Tcp-1 and Tcp-1x genes | journal = Genomics | volume = 18 | issue = 2 | pages = 195–8 | year = 1994 | pmid = 7904580 | doi = 10.1006/geno.1993.1454 }}
*{{cite journal  | author=Fonatsch C, Gradl G, Ragoussis J, Ziegler A |title=Assignment of the TCP1 locus to the long arm of human chromosome 6 by in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=45 |issue= 2 |pages= 109-12 |year= 1987 |pmid= 3476253 |doi= }}
* {{cite journal | vauthors = Miklos D, Caplan S, Mertens D, Hynes G, Pitluk Z, Kashi Y, Harrison-Lavoie K, Stevenson S, Brown C, Barrell B | title = Primary structure and function of a second essential member of the heterooligomeric TCP1 chaperonin complex of yeast, TCP1 beta | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 91 | issue = 7 | pages = 2743–7 | year = 1994 | pmid = 7908441 | pmc = 43446 | doi = 10.1073/pnas.91.7.2743 }}
*{{cite journal  | author=Willison K, Kelly A, Dudley K, ''et al.'' |title=The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region. |journal=EMBO J. |volume=6 |issue= 7 |pages= 1967-74 |year= 1987 |pmid= 3653076 |doi=  }}
* {{cite journal | vauthors = Chen X, Sullivan DS, Huffaker TC | title = Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 91 | issue = 19 | pages = 9111–5 | year = 1994 | pmid = 7916460 | pmc = 44757 | doi = 10.1073/pnas.91.19.9111 }}
*{{cite journal | author=Roobol A, Holmes FE, Hayes NV, ''et al.'' |title=Cytoplasmic chaperonin complexes enter neurites developing in vitro and differ in subunit composition within single cells. |journal=J. Cell. Sci. |volume=108 ( Pt 4) |issue= |pages= 1477-88 |year= 1995 |pmid= 7615668 |doi=  }}
* {{cite journal | vauthors = Kubota H, Hynes G, Carne A, Ashworth A, Willison K | title = Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin | journal = Curr. Biol. | volume = 4 | issue = 2 | pages = 89–99 | year = 1994 | pmid = 7953530 | doi = 10.1016/S0960-9822(94)00024-2 }}
*{{cite journal | author=Ashworth A |title=Two acetyl-CoA acetyltransferase genes located in the t-complex region of mouse chromosome 17 partially overlap the Tcp-1 and Tcp-1x genes. |journal=Genomics |volume=18 |issue= 2 |pages= 195-8 |year= 1994 |pmid= 7904580 |doi= 10.1006/geno.1993.1454 }}
* {{cite journal | vauthors = Frydman J, Hartl FU | title = Principles of chaperone-assisted protein folding: differences between in vitro and in vivo mechanisms | journal = Science | volume = 272 | issue = 5267 | pages = 1497–502 | year = 1996 | pmid = 8633246 | doi = 10.1126/science.272.5267.1497 }}
*{{cite journal | author=Miklos D, Caplan S, Mertens D, ''et al.'' |title=Primary structure and function of a second essential member of the heterooligomeric TCP1 chaperonin complex of yeast, TCP1 beta. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 7 |pages= 2743-7 |year= 1994 |pmid= 7908441 |doi= }}
* {{cite journal | vauthors = Moudjou M, Bordes N, Paintrand M, Bornens M | title = gamma-Tubulin in mammalian cells: the centrosomal and the cytosolic forms | journal = J. Cell Sci. | volume = 109 | issue = 4 | pages = 875–87 | year = 1996 | pmid = 8718679 | doi =  }}
*{{cite journal | author=Chen X, Sullivan DS, Huffaker TC |title=Two yeast genes with similarity to TCP-1 are required for microtubule and actin function in vivo. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=91 |issue= 19 |pages= 9111-5 |year= 1994 |pmid= 7916460 |doi= }}
* {{cite journal | vauthors = Morrison K, Papapetrou C, Attwood J, Hol F, Lynch SA, Sampath A, Hamel B, Burn J, Sowden J, Stott D, Mariman E, Edwards YH | title = Genetic mapping of the human homologue (T) of mouse T(Brachyury) and a search for allele association between human T and spina bifida | journal = Hum. Mol. Genet. | volume = 5 | issue = 5 | pages = 669–74 | year = 1997 | pmid = 8733136 | doi = 10.1093/hmg/5.5.669 }}
*{{cite journal | author=Kubota H, Hynes G, Carne A, ''et al.'' |title=Identification of six Tcp-1-related genes encoding divergent subunits of the TCP-1-containing chaperonin. |journal=Curr. Biol. |volume=4 |issue= 2 |pages= 89-99 |year= 1994 |pmid= 7953530 |doi= }}
* {{cite journal | vauthors = Masuno M, Fukao T, Song XQ, Yamaguchi S, Orii T, Kondo N, Imaizumi K, Kuroki Y | title = Assignment of the human cytosolic acetoacetyl-coenzyme A thiolase (ACAT2) gene to chromosome 6q25.3-q26 | journal = Genomics | volume = 36 | issue = 1 | pages = 217–8 | year = 1997 | pmid = 8812443 | doi = 10.1006/geno.1996.0452 }}
*{{cite journal | author=Frydman J, Hartl FU |title=Principles of chaperone-assisted protein folding: differences between in vitro and in vivo mechanisms. |journal=Science |volume=272 |issue= 5267 |pages= 1497-502 |year= 1996 |pmid= 8633246 |doi= }}
*{{cite journal | author=Moudjou M, Bordes N, Paintrand M, Bornens M |title=gamma-Tubulin in mammalian cells: the centrosomal and the cytosolic forms. |journal=J. Cell. Sci. |volume=109 ( Pt 4) |issue= |pages= 875-87 |year= 1996 |pmid= 8718679 |doi=  }}
*{{cite journal | author=Morrison K, Papapetrou C, Attwood J, ''et al.'' |title=Genetic mapping of the human homologue (T) of mouse T(Brachyury) and a search for allele association between human T and spina bifida. |journal=Hum. Mol. Genet. |volume=5 |issue= 5 |pages= 669-74 |year= 1997 |pmid= 8733136 |doi= }}
*{{cite journal | author=Masuno M, Fukao T, Song XQ, ''et al.'' |title=Assignment of the human cytosolic acetoacetyl-coenzyme A thiolase (ACAT2) gene to chromosome 6q25.3-q26. |journal=Genomics |volume=36 |issue= 1 |pages= 217-8 |year= 1997 |pmid= 8812443 |doi= 10.1006/geno.1996.0452 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
 
{{WikiDoc Sources}}
{{gene-6-stub}}

Latest revision as of 05:10, 25 November 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

T-complex protein 1 subunit alpha is a protein that in humans is encoded by the TCP1 gene.[1][2][3]

Function

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.[3]

Interactions

T-complex 1 has been shown to interact with PPP4C[4][5] and HDAC3.[6] CCT also directly interacts with lectin type oxidized LDL receptor-1 (LOX-1) while its ligand oxidized low density lipoprotein (OxLDL) disassociates CCT from LOX-1.[7]

References

  1. ↑ Fonatsch C, Gradl G, Ragoussis J, Ziegler A (Oct 1987). "Assignment of the TCP1 locus to the long arm of human chromosome 6 by in situ hybridization". Cytogenet Cell Genet. 45 (2): 109–12. doi:10.1159/000132439. PMID 3476253.
  2. ↑ Willison K, Kelly A, Dudley K, Goodfellow P, Spurr N, Groves V, Gorman P, Sheer D, Trowsdale J (Nov 1987). "The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region". EMBO J. 6 (7): 1967–74. PMC 553584. PMID 3653076.
  3. ↑ 3.0 3.1 "Entrez Gene: TCP1 t-complex 1".
  4. ↑ Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC (Oct 2008). "PP4R4/KIAA1622 Forms a Novel Stable Cytosolic Complex with Phosphoprotein Phosphatase 4". J. Biol. Chem. 283 (43): 29273–84. doi:10.1074/jbc.M803443200. PMC 2662017. PMID 18715871.
  5. ↑ Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R (Nov 2005). "A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity". Mol. Cell. Proteomics. 4 (11): 1725–40. doi:10.1074/mcp.M500231-MCP200. PMID 16085932.
  6. ↑ Guenther MG, Yu J, Kao GD, Yen TJ, Lazar MA (Dec 2002). "Assembly of the SMRT–histone deacetylase 3 repression complex requires the TCP-1 ring complex". Genes Dev. 16 (24): 3130–5. doi:10.1101/gad.1037502. PMC 187500. PMID 12502735.
  7. ↑ Bakthavatsalam D, Soung RH, Tweardy DJ, Chiu W, Dixon RA, Woodside DG (Jun 2014). "Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor". FEBS Lett. 588 (13): 2133–40. doi:10.1016/j.febslet.2014.04.049. PMC 4100626. PMID 24846140.

Further reading


Retrieved from "https://www.wikidoc.org/index.php?title=T-complex_1&oldid=1420961"