PPP1R9A: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''Neurabin-1''' is a [[protein]] that in humans is encoded by the ''PPP1R9A'' [[gene]].<ref name="pmid10574462">{{cite journal |vauthors=Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 6 | issue = 5 | pages = 337–45 |date=Jan 2000 | pmid = 10574462 | pmc =  | doi =10.1093/dnares/6.5.337 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: PPP1R9A protein phosphatase 1, regulatory (inhibitor) subunit 9A| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55607| accessdate = }}</ref>
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{{GNF_Protein_box
| image = PBB_Protein_PPP1R9A_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 1wf8.
| PDB = {{PDB2|1wf8}}, {{PDB2|2fn5}}
| Name = Protein phosphatase 1, regulatory (inhibitor) subunit 9A
| HGNCid = 14946
| Symbol = PPP1R9A
| AltSymbols =; FLJ20068; KIAA1222; NRB1; NRBI; Neurabin-I
| OMIM = 602468
| ECnumber = 
| Homologene = 14247
| MGIid = 2442401
| GeneAtlas_image1 = PBB_GE_PPP1R9A_221088_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_PPP1R9A_gnf1h06702_at_tn.png
| Function = {{GNF_GO|id=GO:0003779 |text = actin binding}} {{GNF_GO|id=GO:0005515 |text = protein binding}}
| Component = {{GNF_GO|id=GO:0005856 |text = cytoskeleton}} {{GNF_GO|id=GO:0030175 |text = filopodium}} {{GNF_GO|id=GO:0030864 |text = cortical actin cytoskeleton}} {{GNF_GO|id=GO:0043197 |text = dendritic spine}}
  | Process = {{GNF_GO|id=GO:0007015 |text = actin filament organization}} {{GNF_GO|id=GO:0007275 |text = multicellular organismal development}} {{GNF_GO|id=GO:0007399 |text = nervous system development}} {{GNF_GO|id=GO:0030154 |text = cell differentiation}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 55607
    | Hs_Ensembl = ENSG00000158528
    | Hs_RefseqProtein = NP_060120
    | Hs_RefseqmRNA = NM_017650
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 7
    | Hs_GenLoc_start = 94377362
    | Hs_GenLoc_end = 94760677
    | Hs_Uniprot = Q9ULJ8
    | Mm_EntrezGene = 243725
    | Mm_Ensembl = ENSMUSG00000032827
    | Mm_RefseqmRNA = NM_181595
    | Mm_RefseqProtein = NP_853626
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 6
    | Mm_GenLoc_start = 4853320
    | Mm_GenLoc_end = 5115661
    | Mm_Uniprot =  
  }}
}}
'''Protein phosphatase 1, regulatory (inhibitor) subunit 9A''', also known as '''PPP1R9A''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: PPP1R9A protein phosphatase 1, regulatory (inhibitor) subunit 9A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55607| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal  | author=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1-2 |pages= 171-4 |year= 1994 |pmid= 8125298 |doi=  }}
*{{cite journal  |vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8 }}
*{{cite journal  | author=Nakanishi H, Obaishi H, Satoh A, ''et al.'' |title=Neurabin: a novel neural tissue-specific actin filament-binding protein involved in neurite formation. |journal=J. Cell Biol. |volume=139 |issue= 4 |pages= 951-61 |year= 1997 |pmid= 9362513 |doi=  }}
*{{cite journal  | author=Nakanishi H |title=Neurabin: A Novel Neural Tissue–specific Actin Filament–binding Protein Involved in Neurite Formation |journal=J. Cell Biol. |volume=139 |issue= 4 |pages= 951–61 |year= 1997 |pmid= 9362513 |doi=10.1083/jcb.139.4.951  | pmc=2139968  |name-list-format=vanc| author2=Obaishi H  | author3=Satoh A  | display-authors=3  | last4=Wada  | first4=M  | last5=Mandai  | first5=K  | last6=Satoh  | first6=K  | last7=Nishioka  | first7=H  | last8=Matsuura  | first8=Y  | last9=Mizoguchi  | first9=A }}
*{{cite journal  | author=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, ''et al.'' |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library. |journal=Gene |volume=200 |issue= 1-2 |pages= 149-56 |year= 1997 |pmid= 9373149 |doi=  }}
*{{cite journal  | author=Suzuki Y |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |name-list-format=vanc| author2=Yoshitomo-Nakagawa K  | author3=Maruyama K  | display-authors=3  | last4=Suyama  | first4=A  | last5=Sugano  | first5=S }}
*{{cite journal  | author=McAvoy T, Allen PB, Obaishi H, ''et al.'' |title=Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation. |journal=Biochemistry |volume=38 |issue= 39 |pages= 12943-9 |year= 1999 |pmid= 10504266 |doi=  }}
*{{cite journal  | author=McAvoy T |title=Regulation of neurabin I interaction with protein phosphatase 1 by phosphorylation |journal=Biochemistry |volume=38 |issue= 39 |pages= 12943–9 |year= 1999 |pmid= 10504266 |doi=10.1021/bi991227d  |name-list-format=vanc| author2=Allen PB  | author3=Obaishi H  | display-authors=3  | last4=Nakanishi  | first4=Hiroyuki  | last5=Takai  | first5=Yoshimi  | last6=Greengard  | first6=Paul  | last7=Nairn  | first7=Angus C.  | last8=Hemmings  | first8=Hugh C. }}
*{{cite journal  | author=Stephens DJ, Banting G |title=Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin. |journal=J. Biol. Chem. |volume=274 |issue= 42 |pages= 30080-6 |year= 1999 |pmid= 10514494 |doi=  }}
*{{cite journal  |vauthors=Stephens DJ, Banting G |title=Direct interaction of the trans-Golgi network membrane protein, TGN38, with the F-actin binding protein, neurabin |journal=J. Biol. Chem. |volume=274 |issue= 42 |pages= 30080–6 |year= 1999 |pmid= 10514494 |doi=10.1074/jbc.274.42.30080 }}
*{{cite journal  | author=Nagase T, Ishikawa K, Kikuno R, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=6 |issue= 5 |pages= 337-45 |year= 2000 |pmid= 10574462 |doi=  }}
*{{cite journal  | author=Oliver CJ |title=Targeting Protein Phosphatase 1 (PP1) to the Actin Cytoskeleton: the Neurabin I/PP1 Complex Regulates Cell Morphology |journal=Mol. Cell. Biol. |volume=22 |issue= 13 |pages= 4690–701 |year= 2002 |pmid= 12052877 |doi=10.1128/MCB.22.13.4690-4701.2002 | pmc=133892 |name-list-format=vanc| author2=Terry-Lorenzo RT | author3=Elliott E | display-authors=3  | last4=Bloomer  | first4=W. A. C. | last5=Li  | first5=S. | last6=Brautigan  | first6=D. L.  | last7=Colbran  | first7=R. J.  | last8=Shenolikar  | first8=S. }}
*{{cite journal | author=Oliver CJ, Terry-Lorenzo RT, Elliott E, ''et al.'' |title=Targeting protein phosphatase 1 (PP1) to the actin cytoskeleton: the neurabin I/PP1 complex regulates cell morphology. |journal=Mol. Cell. Biol. |volume=22 |issue= 13 |pages= 4690-701 |year= 2002 |pmid= 12052877 |doi=  }}
*{{cite journal  | author=Strausberg RL |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241  |name-list-format=vanc| author2=Feingold EA  | author3=Grouse LH  | display-authors=3  | last4=Derge  | first4=JG  | last5=Klausner  | first5=RD  | last6=Collins  | first6=FS  | last7=Wagner  | first7=L  | last8=Shenmen  | first8=CM  | last9=Schuler  | first9=GD }}
*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal  | author=Scherer SW |title=Human Chromosome 7: DNA Sequence and Biology |journal=Science |volume=300 |issue= 5620 |pages= 767–72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 | pmc=2882961  |name-list-format=vanc| author2=Cheung J  | author3=MacDonald JR  | display-authors=3  | last4=Osborne  | first4=LR  | last5=Nakabayashi  | first5=K  | last6=Herbrick  | first6=JA  | last7=Carson  | first7=AR  | last8=Parker-Katiraee  | first8=L  | last9=Skaug  | first9=J }}
*{{cite journal  | author=Scherer SW, Cheung J, MacDonald JR, ''et al.'' |title=Human chromosome 7: DNA sequence and biology. |journal=Science |volume=300 |issue= 5620 |pages= 767-72 |year= 2003 |pmid= 12690205 |doi= 10.1126/science.1083423 }}
*{{cite journal  | author=Hillier LW |title=The DNA sequence of human chromosome 7 |journal=Nature |volume=424 |issue= 6945 |pages= 157–64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 |name-list-format=vanc| author2=Fulton RS  | author3=Fulton LA  | display-authors=3  | last4=Graves  | first4=Tina A.  | last5=Pepin  | first5=Kymberlie H.  | last6=Wagner-Mcpherson  | first6=Caryn  | last7=Layman  | first7=Dan  | last8=Maas  | first8=Jason  | last9=Jaeger  | first9=Sara }}
*{{cite journal  | author=Hillier LW, Fulton RS, Fulton LA, ''et al.'' |title=The DNA sequence of human chromosome 7. |journal=Nature |volume=424 |issue= 6945 |pages= 157-64 |year= 2003 |pmid= 12853948 |doi= 10.1038/nature01782 }}
*{{cite journal  | author=Ota T |title=Complete sequencing and characterization of 21,243 full-length human cDNAs |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 |name-list-format=vanc| author2=Suzuki Y  | author3=Nishikawa T  | display-authors=3  | last4=Otsuki  | first4=Tetsuji  | last5=Sugiyama  | first5=Tomoyasu  | last6=Irie  | first6=Ryotaro  | last7=Wakamatsu  | first7=Ai  | last8=Hayashi  | first8=Koji  | last9=Sato  | first9=Hiroyuki }}
*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal  | author=Kimura K |title=Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes |journal=Genome Res. |volume=16 |issue= 1 |pages= 55–65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 | pmc=1356129  |name-list-format=vanc| author2=Wakamatsu A  | author3=Suzuki Y  | display-authors=3  | last4=Ota  | first4=T  | last5=Nishikawa  | first5=T  | last6=Yamashita  | first6=R  | last7=Yamamoto  | first7=J  | last8=Sekine  | first8=M  | last9=Tsuritani  | first9=K }}
*{{cite journal  | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
}}
}}
{{refend}}
{{refend}}
{{PDB Gallery|geneid=55607}}
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Latest revision as of 18:34, 7 September 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Neurabin-1 is a protein that in humans is encoded by the PPP1R9A gene.[1][2]


References

  1. ↑ Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O (Jan 2000). "Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (5): 337–45. doi:10.1093/dnares/6.5.337. PMID 10574462.
  2. ↑ "Entrez Gene: PPP1R9A protein phosphatase 1, regulatory (inhibitor) subunit 9A".

Further reading



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