RB1CC1: Difference between revisions

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{{Infobox_gene}}
{{PBB_Controls
'''RB1-inducible coiled-coil protein 1''' is a [[protein]] that in humans is encoded by the ''RB1CC1'' [[gene]].<ref name="pmid11850849">{{cite journal | vauthors = Chano T, Ikegawa S, Kontani K, Okabe H, Baldini N, Saeki Y | title = Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells | journal = Oncogene | volume = 21 | issue = 8 | pages = 1295–8 | date = Feb 2002 | pmid = 11850849 | pmc =  | doi = 10.1038/sj.onc.1205171 }}</ref><ref name="pmid7724523">{{cite journal | vauthors = Maucuer A, Camonis JH, Sobel A | title = Stathmin interaction with a putative kinase and coiled-coil-forming protein domains | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 92 | issue = 8 | pages = 3100–4 | date = Apr 1995 | pmid = 7724523 | pmc = 42112 | doi = 10.1073/pnas.92.8.3100 }}</ref><ref name="pmid18443221">{{cite journal | vauthors = Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N | title = FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells | journal = The Journal of Cell Biology | volume = 181 | issue = 3 | pages = 497–510 | date = May 2008 | pmid = 18443221 | pmc = 2364687 | doi = 10.1083/jcb.200712064 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: RB1CC1 RB1-inducible coiled-coil 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9821| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Interactions ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = RB1-inducible coiled-coil 1
| HGNCid = 15574
| Symbol = RB1CC1
| AltSymbols =; CC1; DRAGOU14; FIP200
| OMIM = 606837
| ECnumber = 
| Homologene = 7659
| MGIid = 1341850
| GeneAtlas_image1 = PBB_GE_RB1CC1_202033_s_at_tn.png
| GeneAtlas_image2 = PBB_GE_RB1CC1_202034_x_at_tn.png
| Function =
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0007049 |text = cell cycle}} {{GNF_GO|id=GO:0045786 |text = negative regulation of progression through cell cycle}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 9821
    | Hs_Ensembl = ENSG00000023287
    | Hs_RefseqProtein = NP_055596
    | Hs_RefseqmRNA = NM_014781
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 8
    | Hs_GenLoc_start = 53697569
    | Hs_GenLoc_end = 53789545
    | Hs_Uniprot = Q8TDY2
    | Mm_EntrezGene = 12421
    | Mm_Ensembl = ENSMUSG00000025907
    | Mm_RefseqmRNA = NM_009826
    | Mm_RefseqProtein = NP_033956
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 1
    | Mm_GenLoc_start = 6204743
    | Mm_GenLoc_end = 6265656
    | Mm_Uniprot = Q6NZG0
  }}
}}
'''RB1-inducible coiled-coil 1''', also known as '''RB1CC1''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: RB1CC1 RB1-inducible coiled-coil 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9821| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
RB1CC1 has been shown to [[Protein-protein interaction|interact]] with [[PTK2B]],<ref name=pmid10769033>{{cite journal | vauthors = Ueda H, Abbi S, Zheng C, Guan JL | title = Suppression of Pyk2 kinase and cellular activities by FIP200 | journal = The Journal of Cell Biology | volume = 149 | issue = 2 | pages = 423–30 | date = Apr 2000 | pmid = 10769033 | pmc = 2175150 | doi = 10.1083/jcb.149.2.423 }}</ref> [[ASK1]]<ref name=pmid17015619>{{cite journal | vauthors = Gan B, Peng X, Nagy T, Alcaraz A, Gu H, Guan JL | title = Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways | journal = The Journal of Cell Biology | volume = 175 | issue = 1 | pages = 121–33 | date = Oct 2006 | pmid = 17015619 | pmc = 2064504 | doi = 10.1083/jcb.200604129 }}</ref> and [[PTK2]].<ref name=pmid10769033/>
{{PBB_Summary
| section_title =  
| summary_text =  
}}


==References==
== References ==
{{reflist|2}}
{{reflist}}
==Further reading==
 
== Further reading ==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading
* {{cite journal | vauthors = Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N | title = Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain | journal = DNA Research | volume = 3 | issue = 5 | pages = 321–9, 341-54 | date = Oct 1996 | pmid = 9039502 | doi = 10.1093/dnares/3.5.321 }}
| citations =
* {{cite journal | vauthors = Ueda H, Abbi S, Zheng C, Guan JL | title = Suppression of Pyk2 kinase and cellular activities by FIP200 | journal = The Journal of Cell Biology | volume = 149 | issue = 2 | pages = 423–30 | date = Apr 2000 | pmid = 10769033 | pmc = 2175150 | doi = 10.1083/jcb.149.2.423 }}
*{{cite journal  | author=Maucuer A, Camonis JH, Sobel A |title=Stathmin interaction with a putative kinase and coiled-coil-forming protein domains. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 8 |pages= 3100-4 |year= 1995 |pmid= 7724523 |doi=  }}
* {{cite journal | vauthors = Chano T, Kontani K, Teramoto K, Okabe H, Ikegawa S | title = Truncating mutations of RB1CC1 in human breast cancer | journal = Nature Genetics | volume = 31 | issue = 3 | pages = 285–8 | date = Jul 2002 | pmid = 12068296 | doi = 10.1038/ng911 }}
*{{cite journal | author=Nagase T, Seki N, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. |journal=DNA Res. |volume=3 |issue= 5 |pages= 321-9, 341-54 |year= 1997 |pmid= 9039502 |doi= }}
* {{cite journal | vauthors = Chano T, Ikegawa S, Saito-Ohara F, Inazawa J, Mabuchi A, Saeki Y, Okabe H | title = Isolation, characterization and mapping of the mouse and human RB1CC1 genes | journal = Gene | volume = 291 | issue = 1-2 | pages = 29–34 | date = May 2002 | pmid = 12095676 | doi = 10.1016/S0378-1119(02)00585-1 }}
*{{cite journal | author=Ueda H, Abbi S, Zheng C, Guan JL |title=Suppression of Pyk2 kinase and cellular activities by FIP200. |journal=J. Cell Biol. |volume=149 |issue= 2 |pages= 423-30 |year= 2000 |pmid= 10769033 |doi=  }}
* {{cite journal | vauthors = Chano T, Saeki Y, Serra M, Matsumoto K, Okabe H | title = Preferential expression of RB1-inducible coiled-coil 1 in terminal differentiated musculoskeletal cells | journal = The American Journal of Pathology | volume = 161 | issue = 2 | pages = 359–64 | date = Aug 2002 | pmid = 12163359 | pmc = 1850752 | doi = 10.1016/S0002-9440(10)64190-9 }}
*{{cite journal  | author=Chano T, Ikegawa S, Kontani K, ''et al.'' |title=Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells. |journal=Oncogene |volume=21 |issue= 8 |pages= 1295-8 |year= 2002 |pmid= 11850849 |doi= 10.1038/sj.onc.1205171 }}
* {{cite journal | vauthors = Abbi S, Ueda H, Zheng C, Cooper LA, Zhao J, Christopher R, Guan JL | title = Regulation of focal adhesion kinase by a novel protein inhibitor FIP200 | journal = Molecular Biology of the Cell | volume = 13 | issue = 9 | pages = 3178–91 | date = Sep 2002 | pmid = 12221124 | pmc = 124151 | doi = 10.1091/mbc.E02-05-0295 }}
*{{cite journal | author=Chano T, Kontani K, Teramoto K, ''et al.'' |title=Truncating mutations of RB1CC1 in human breast cancer. |journal=Nat. Genet. |volume=31 |issue= 3 |pages= 285-8 |year= 2002 |pmid= 12068296 |doi= 10.1038/ng911 }}
* {{cite journal | vauthors = Kontani K, Chano T, Ozaki Y, Tezuka N, Sawai S, Fujino S, Saeki Y, Okabe H | title = RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells | journal = International Journal of Molecular Medicine | volume = 12 | issue = 5 | pages = 767–9 | date = Nov 2003 | pmid = 14533007 | doi = 10.3892/ijmm.12.5.767 }}
*{{cite journal | author=Chano T, Ikegawa S, Saito-Ohara F, ''et al.'' |title=Isolation, characterization and mapping of the mouse and human RB1CC1 genes. |journal=Gene |volume=291 |issue= 1-2 |pages= 29-34 |year= 2002 |pmid= 12095676 |doi= }}
* {{cite journal | vauthors = Bamba N, Chano T, Taga T, Ohta S, Takeuchi Y, Okabe H | title = Expression and regulation of RB1CC1 in developing murine and human tissues | journal = International Journal of Molecular Medicine | volume = 14 | issue = 4 | pages = 583–7 | date = Oct 2004 | pmid = 15375585 | doi = 10.3892/ijmm.14.4.583 }}
*{{cite journal | author=Chano T, Saeki Y, Serra M, ''et al.'' |title=Preferential expression of RB1-inducible coiled-coil 1 in terminal differentiated musculoskeletal cells. |journal=Am. J. Pathol. |volume=161 |issue= 2 |pages= 359-64 |year= 2002 |pmid= 12163359 |doi= }}
* {{cite journal | vauthors = Watanabe R, Chano T, Inoue H, Isono T, Koiwai O, Okabe H | title = Rb1cc1 is critical for myoblast differentiation through Rb1 regulation | journal = Virchows Archiv | volume = 447 | issue = 3 | pages = 643–8 | date = Sep 2005 | pmid = 15968549 | doi = 10.1007/s00428-004-1183-1 }}
*{{cite journal | author=Abbi S, Ueda H, Zheng C, ''et al.'' |title=Regulation of focal adhesion kinase by a novel protein inhibitor FIP200. |journal=Mol. Biol. Cell |volume=13 |issue= 9 |pages= 3178-91 |year= 2003 |pmid= 12221124 |doi= 10.1091/mbc.E02-05-0295 }}
* {{cite journal | vauthors = Gan B, Melkoumian ZK, Wu X, Guan KL, Guan JL | title = Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control | journal = The Journal of Cell Biology | volume = 170 | issue = 3 | pages = 379–89 | date = Aug 2005 | pmid = 16043512 | pmc = 2171462 | doi = 10.1083/jcb.200411106 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
* {{cite journal | vauthors = Melkoumian ZK, Peng X, Gan B, Wu X, Guan JL | title = Mechanism of cell cycle regulation by FIP200 in human breast cancer cells | journal = Cancer Research | volume = 65 | issue = 15 | pages = 6676–84 | date = Aug 2005 | pmid = 16061648 | doi = 10.1158/0008-5472.CAN-04-4142 }}
*{{cite journal  | author=Kontani K, Chano T, Ozaki Y, ''et al.'' |title=RB1CC1 suppresses cell cycle progression through RB1 expression in human neoplastic cells. |journal=Int. J. Mol. Med. |volume=12 |issue= 5 |pages= 767-9 |year= 2004 |pmid= 14533007 |doi= }}
* {{cite journal | vauthors = Chano T, Saji M, Inoue H, Minami K, Kobayashi T, Hino O, Okabe H | title = Neuromuscular abundance of RB1CC1 contributes to the non-proliferating enlarged cell phenotype through both RB1 maintenance and TSC1 degradation | journal = International Journal of Molecular Medicine | volume = 18 | issue = 3 | pages = 425–32 | date = Sep 2006 | pmid = 16865226 | doi = 10.3892/ijmm.18.3.425 }}
*{{cite journal | author=Bamba N, Chano T, Taga T, ''et al.'' |title=Expression and regulation of RB1CC1 in developing murine and human tissues. |journal=Int. J. Mol. Med. |volume=14 |issue= 4 |pages= 583-7 |year= 2005 |pmid= 15375585 |doi= }}
* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = Nov 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 }}
*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
* {{cite journal | vauthors = Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D | title = Large-scale mapping of human protein-protein interactions by mass spectrometry | journal = Molecular Systems Biology | volume = 3 | issue = 1 | pages = 89 | year = 2007 | pmid = 17353931 | pmc = 1847948 | doi = 10.1038/msb4100134 }}
*{{cite journal | author=Watanabe R, Chano T, Inoue H, ''et al.'' |title=Rb1cc1 is critical for myoblast differentiation through Rb1 regulation. |journal=Virchows Arch. |volume=447 |issue= 3 |pages= 643-8 |year= 2005 |pmid= 15968549 |doi= 10.1007/s00428-004-1183-1 }}
* {{cite journal | vauthors = Lee YC, Yang VC, Wang TS | title = Use of RAPD to detect sodium arsenite-induced DNA damage in human lymphoblastoid cells | journal = Toxicology | volume = 239 | issue = 1-2 | pages = 108–15 | date = Sep 2007 | pmid = 17707572 | doi = 10.1016/j.tox.2007.06.101 }}
*{{cite journal | author=Gan B, Melkoumian ZK, Wu X, ''et al.'' |title=Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control. |journal=J. Cell Biol. |volume=170 |issue= 3 |pages= 379-89 |year= 2005 |pmid= 16043512 |doi= 10.1083/jcb.200411106 }}
*{{cite journal | author=Melkoumian ZK, Peng X, Gan B, ''et al.'' |title=Mechanism of cell cycle regulation by FIP200 in human breast cancer cells. |journal=Cancer Res. |volume=65 |issue= 15 |pages= 6676-84 |year= 2005 |pmid= 16061648 |doi= 10.1158/0008-5472.CAN-04-4142 }}
*{{cite journal | author=Kimura K, Wakamatsu A, Suzuki Y, ''et al.'' |title=Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. |journal=Genome Res. |volume=16 |issue= 1 |pages= 55-65 |year= 2006 |pmid= 16344560 |doi= 10.1101/gr.4039406 }}
*{{cite journal  | author=Chano T, Saji M, Inoue H, ''et al.'' |title=Neuromuscular abundance of RB1CC1 contributes to the non-proliferating enlarged cell phenotype through both RB1 maintenance and TSC1 degradation. |journal=Int. J. Mol. Med. |volume=18 |issue= 3 |pages= 425-32 |year= 2006 |pmid= 16865226 |doi= }}
*{{cite journal | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
*{{cite journal | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue= |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
*{{cite journal | author=Lee YC, Yang VC, Wang TS |title=Use of RAPD to detect sodium arsenite-induced DNA damage in human lymphoblastoid cells. |journal=Toxicology |volume=239 |issue= 1-2 |pages= 108-15 |year= 2007 |pmid= 17707572 |doi= 10.1016/j.tox.2007.06.101 }}
}}
{{refend}}
{{refend}}


{{protein-stub}}
{{gene-8-stub}}
{{WikiDoc Sources}}

Latest revision as of 08:57, 10 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

RB1-inducible coiled-coil protein 1 is a protein that in humans is encoded by the RB1CC1 gene.[1][2][3][4]

Interactions

RB1CC1 has been shown to interact with PTK2B,[5] ASK1[6] and PTK2.[5]

References

  1. Chano T, Ikegawa S, Kontani K, Okabe H, Baldini N, Saeki Y (Feb 2002). "Identification of RB1CC1, a novel human gene that can induce RB1 in various human cells". Oncogene. 21 (8): 1295–8. doi:10.1038/sj.onc.1205171. PMID 11850849.
  2. Maucuer A, Camonis JH, Sobel A (Apr 1995). "Stathmin interaction with a putative kinase and coiled-coil-forming protein domains". Proceedings of the National Academy of Sciences of the United States of America. 92 (8): 3100–4. doi:10.1073/pnas.92.8.3100. PMC 42112. PMID 7724523.
  3. Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N (May 2008). "FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells". The Journal of Cell Biology. 181 (3): 497–510. doi:10.1083/jcb.200712064. PMC 2364687. PMID 18443221.
  4. "Entrez Gene: RB1CC1 RB1-inducible coiled-coil 1".
  5. 5.0 5.1 Ueda H, Abbi S, Zheng C, Guan JL (Apr 2000). "Suppression of Pyk2 kinase and cellular activities by FIP200". The Journal of Cell Biology. 149 (2): 423–30. doi:10.1083/jcb.149.2.423. PMC 2175150. PMID 10769033.
  6. Gan B, Peng X, Nagy T, Alcaraz A, Gu H, Guan JL (Oct 2006). "Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways". The Journal of Cell Biology. 175 (1): 121–33. doi:10.1083/jcb.200604129. PMC 2064504. PMID 17015619.

Further reading