IFNA8: Difference between revisions

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{{Infobox_gene}}
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'''Interferon alpha-8''' is a [[protein]] that in humans is encoded by the ''IFNA8'' [[gene]].<ref name="pmid1385305">{{cite journal |vauthors=Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO | title = Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia | journal = Genomics | volume = 14 | issue = 2 | pages = 437–43 |date=Dec 1992 | pmid = 1385305 | pmc =  | doi =10.1016/S0888-7543(05)80238-1 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: IFNA8 interferon, alpha 8| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3445| accessdate = }}</ref>
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{{GNF_Protein_box
| image =
| image_source =
| PDB =  
| Name = Interferon, alpha 8
| HGNCid = 5429
| Symbol = IFNA8
| AltSymbols =;
| OMIM = 147568
| ECnumber =
| Homologene = 68237
| MGIid =
  | GeneAtlas_image1 = PBB_GE_IFNA8_207932_at_tn.png
| Function = {{GNF_GO|id=GO:0005126 |text = hematopoietin/interferon-class (D200-domain) cytokine receptor binding}}
  | Component = {{GNF_GO|id=GO:0005576 |text = extracellular region}} {{GNF_GO|id=GO:0005615 |text = extracellular space}}
| Process = {{GNF_GO|id=GO:0006952 |text = defense response}} {{GNF_GO|id=GO:0009615 |text = response to virus}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 3445
    | Hs_Ensembl = ENSG00000120242
    | Hs_RefseqProtein = NP_002161
    | Hs_RefseqmRNA = NM_002170
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = 9
    | Hs_GenLoc_start = 21399146
    | Hs_GenLoc_end = 21400184
    | Hs_Uniprot = P32881
    | Mm_EntrezGene = 
    | Mm_Ensembl = 
    | Mm_RefseqmRNA = 
    | Mm_RefseqProtein = 
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 
    | Mm_GenLoc_start = 
    | Mm_GenLoc_end = 
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'''Interferon, alpha 8''', also known as '''IFNA8''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: IFNA8 interferon, alpha 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3445| accessdate = }}</ref>


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==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Olopade OI, Bohlander SK, Pomykala H, ''et al.'' |title=Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. |journal=Genomics |volume=14 |issue= 2 |pages= 437-43 |year= 1992 |pmid= 1385305 |doi=  }}
*{{cite journal   |vauthors=Henco K, Brosius J, Fujisawa A, etal |title=Structural relationship of human interferon alpha genes and pseudogenes. |journal=J. Mol. Biol. |volume=185 |issue= 2 |pages= 227–60 |year= 1985 |pmid= 4057246 |doi=10.1016/0022-2836(85)90401-2 }}
*{{cite journal  | author=Henco K, Brosius J, Fujisawa A, ''et al.'' |title=Structural relationship of human interferon alpha genes and pseudogenes. |journal=J. Mol. Biol. |volume=185 |issue= 2 |pages= 227-60 |year= 1985 |pmid= 4057246 |doi=  }}
*{{cite journal   |vauthors=Goeddel DV, Leung DW, Dull TJ, etal |title=The structure of eight distinct cloned human leukocyte interferon cDNAs. |journal=Nature |volume=290 |issue= 5801 |pages= 20–6 |year= 1981 |pmid= 6163083 |doi=10.1038/290020a0 }}
*{{cite journal | author=Goeddel DV, Leung DW, Dull TJ, ''et al.'' |title=The structure of eight distinct cloned human leukocyte interferon cDNAs. |journal=Nature |volume=290 |issue= 5801 |pages= 20-6 |year= 1981 |pmid= 6163083 |doi=  }}
*{{cite journal   |vauthors=Yelverton E, Leung D, Weck P, etal |title=Bacterial synthesis of a novel human leukocyte interferon. |journal=Nucleic Acids Res. |volume=9 |issue= 3 |pages= 731–41 |year= 1981 |pmid= 6164048 |doi=10.1093/nar/9.3.731  | pmc=327233 }}
*{{cite journal | author=Yelverton E, Leung D, Weck P, ''et al.'' |title=Bacterial synthesis of a novel human leukocyte interferon. |journal=Nucleic Acids Res. |volume=9 |issue= 3 |pages= 731-41 |year= 1981 |pmid= 6164048 |doi=  }}
*{{cite journal   |vauthors=Bowden DW, Mao J, Gill T, etal |title=Cloning of eukaryotic genes in single-strand phage vectors: the human interferon genes. |journal=Gene |volume=27 |issue= 1 |pages= 87–99 |year= 1984 |pmid= 6325303 |doi=10.1016/0378-1119(84)90241-5 }}
*{{cite journal | author=Bowden DW, Mao J, Gill T, ''et al.'' |title=Cloning of eukaryotic genes in single-strand phage vectors: the human interferon genes. |journal=Gene |volume=27 |issue= 1 |pages= 87-99 |year= 1984 |pmid= 6325303 |doi=  }}
*{{cite journal   |vauthors=Tiefenbrun N, Melamed D, Levy N, etal |title=Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3934–44 |year= 1996 |pmid= 8668211 |doi= | pmc=231390 }}
*{{cite journal | author=Tiefenbrun N, Melamed D, Levy N, ''et al.'' |title=Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest. |journal=Mol. Cell. Biol. |volume=16 |issue= 7 |pages= 3934-44 |year= 1996 |pmid= 8668211 |doi=  }}
*{{cite journal  |vauthors=Hussain M, Gill DS, Liao MJ, Testa D |title=Interferon-alpha 8b is the only variant of interferon-alpha 8 identified in a large human population. |journal=J. Interferon Cytokine Res. |volume=16 |issue= 7 |pages= 523–9 |year= 1997 |pmid= 8836918 |doi= 10.1089/jir.1996.16.523 }}
*{{cite journal  | author=Hussain M, Gill DS, Liao MJ, Testa D |title=Interferon-alpha 8b is the only variant of interferon-alpha 8 identified in a large human population. |journal=J. Interferon Cytokine Res. |volume=16 |issue= 7 |pages= 523-9 |year= 1997 |pmid= 8836918 |doi= }}
*{{cite journal  |vauthors=Nyman TA, Tölö H, Parkkinen J, Kalkkinen N |title=Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes. | series=329 |journal=Biochem. J. |volume=( Pt 2) |issue=  |pages= 295–302 |year= 1998 |pmid= 9425112 |doi= | pmc=1219044 }}
*{{cite journal  | author=Nyman TA, Tölö H, Parkkinen J, Kalkkinen N |title=Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes. |journal=Biochem. J. |volume=329 ( Pt 2) |issue=  |pages= 295-302 |year= 1998 |pmid= 9425112 |doi=  }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Hardy MP, Owczarek CM, Jermiin LS, etal |title=Characterization of the type I interferon locus and identification of novel genes. |journal=Genomics |volume=84 |issue= 2 |pages= 331–45 |year= 2005 |pmid= 15233997 |doi= 10.1016/j.ygeno.2004.03.003 }}
*{{cite journal | author=Hardy MP, Owczarek CM, Jermiin LS, ''et al.'' |title=Characterization of the type I interferon locus and identification of novel genes. |journal=Genomics |volume=84 |issue= 2 |pages= 331-45 |year= 2005 |pmid= 15233997 |doi= 10.1016/j.ygeno.2004.03.003 }}
}}
}}
{{refend}}
{{refend}}
{{Cytokine receptor modulators}}
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{{gene-9-stub}}
{{gene-9-stub}}

Latest revision as of 23:39, 31 August 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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n/a

RefSeq (mRNA)

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RefSeq (protein)

n/a

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Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Interferon alpha-8 is a protein that in humans is encoded by the IFNA8 gene.[1][2]


References

  1. ↑ Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO (Dec 1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia". Genomics. 14 (2): 437–43. doi:10.1016/S0888-7543(05)80238-1. PMID 1385305.
  2. ↑ "Entrez Gene: IFNA8 interferon, alpha 8".

Further reading



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