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{{Infobox_gene}}
{{PBB_Controls
'''Structural maintenance of chromosomes protein 1A''' is a [[protein]] that in humans is encoded by the ''SMC1A'' [[gene]].<ref name="pmid7757074">{{cite journal | vauthors = Rocques PJ, Clark J, Ball S, Crew J, Gill S, Christodoulou Z, Borts RH, Louis EJ, Davies KE, Cooper CS | title = The human SB1.8 gene (DXS423E) encodes a putative chromosome segregation protein conserved in lower eukaryotes and prokaryotes | journal = Hum Mol Genet | volume = 4 | issue = 2 | pages = 243–9 |date=June 1995 | pmid = 7757074 | pmc =  | doi =10.1093/hmg/4.2.243  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SMC1A structural maintenance of chromosomes 1A| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8243| accessdate = }}</ref>
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
== Function ==
{{GNF_Protein_box
| image =
| image_source =
| PDB =
| Name = Structural maintenance of chromosomes 1A
| HGNCid = 11111
| Symbol = SMC1A
| AltSymbols =; DKFZp686L19178; DXS423E; KIAA0178; MGC138332; SB1.8; SMC1; SMC1L1; SMC1alpha; SMCB
| OMIM = 300040
| ECnumber = 
| Homologene = 4597
| MGIid = 1344345
| GeneAtlas_image1 = PBB_GE_SMC1A_201589_at_tn.png
| GeneAtlas_image2 = PBB_GE_SMC1A_217555_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003682 |text = chromatin binding}} {{GNF_GO|id=GO:0003777 |text = microtubule motor activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0016887 |text = ATPase activity}} {{GNF_GO|id=GO:0046982 |text = protein heterodimerization activity}}
| Component = {{GNF_GO|id=GO:0000776 |text = kinetochore}} {{GNF_GO|id=GO:0000794 |text = condensed nuclear chromosome}} {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005694 |text = chromosome}} {{GNF_GO|id=GO:0008280 |text = cohesin core heterodimer}}
| Process = {{GNF_GO|id=GO:0000075 |text = cell cycle checkpoint}} {{GNF_GO|id=GO:0006259 |text = DNA metabolic process}} {{GNF_GO|id=GO:0006281 |text = DNA repair}} {{GNF_GO|id=GO:0007049 |text = cell cycle}} {{GNF_GO|id=GO:0007052 |text = mitotic spindle organization and biogenesis}} {{GNF_GO|id=GO:0007059 |text = chromosome segregation}} {{GNF_GO|id=GO:0007064 |text = mitotic sister chromatid cohesion}} {{GNF_GO|id=GO:0007126 |text = meiosis}} {{GNF_GO|id=GO:0009314 |text = response to radiation}} {{GNF_GO|id=GO:0042770 |text = DNA damage response, signal transduction}} {{GNF_GO|id=GO:0051276 |text = chromosome organization and biogenesis}} {{GNF_GO|id=GO:0051301 |text = cell division}}
| Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 8243
    | Hs_Ensembl = ENSG00000072501
    | Hs_RefseqProtein = NP_006297
    | Hs_RefseqmRNA = NM_006306
    | Hs_GenLoc_db = 
    | Hs_GenLoc_chr = X
    | Hs_GenLoc_start = 53417795
    | Hs_GenLoc_end = 53466343
    | Hs_Uniprot = Q14683
    | Mm_EntrezGene = 24061
    | Mm_Ensembl = ENSMUSG00000041133
    | Mm_RefseqmRNA = NM_019710
    | Mm_RefseqProtein = NP_062684
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = X
    | Mm_GenLoc_start = 147357144
    | Mm_GenLoc_end = 147402683
    | Mm_Uniprot = A0JLM6
  }}
}}
'''Structural maintenance of chromosomes 1A''', also known as '''SMC1A''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SMC1A structural maintenance of chromosomes 1A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8243| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
Proper cohesion of [[sister chromatid]]s is a prerequisite for the correct segregation of [[chromosome]]s during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either [[SMC1L2]] or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with [[BRCA1]] and is [[phosphorylated]] by [[Ataxia telangiectasia mutated|ATM]], indicating a potential role for this protein in [[DNA repair]]. This gene, which belongs to the SMC gene family, is located in an area of the [[X-chromosome]] that escapes [[X inactivation]].<ref name="entrez"/>
{{PBB_Summary
 
| section_title =
==Interactions==
| summary_text = Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.<ref name="entrez">{{cite web | title = Entrez Gene: SMC1A structural maintenance of chromosomes 1A| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8243| accessdate = }}</ref>
SMC1A has been shown to [[Protein-protein interaction|interact]] with [[SMC3 (gene)|SMC3]]<ref name="pmid11877376">{{cite journal | vauthors = Kim ST, Xu B, Kastan MB | title = Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage | journal = Genes Dev. | volume = 16 | issue = 5 | pages = 560–70 |date=March 2002 | pmid = 11877376 | pmc = 155347 | doi = 10.1101/gad.970602 }}</ref><ref name="pmid12759374">{{cite journal | vauthors = Lee J, Iwai T, Yokota T, Yamashita M | title = Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis | journal = J. Cell Sci. | volume = 116 | issue = Pt 13 | pages = 2781–90 |date=July 2003 | pmid = 12759374 | doi = 10.1242/jcs.00495 }}</ref><ref name="pmid9789013">{{cite journal | vauthors = Schmiesing JA, Ball AR, Gregson HC, Alderton JM, Zhou S, Yokomori K | title = Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 95 | issue = 22 | pages = 12906–11 |date=October 1998 | pmid = 9789013 | pmc = 23650 | doi = 10.1073/pnas.95.22.12906 }}</ref><ref name="pmid11590136">{{cite journal | vauthors = Gregson HC, Schmiesing JA, Kim JS, Kobayashi T, Zhou S, Yokomori K | title = A potential role for human cohesin in mitotic spindle aster assembly | journal = J. Biol. Chem. | volume = 276 | issue = 50 | pages = 47575–82 |date=December 2001 | pmid = 11590136 | doi = 10.1074/jbc.M103364200 }}</ref> and [[Ataxia telangiectasia mutated]].<ref name=pmid11877376/>
}}


==See also==
==See also==
* [[SMC protein]]
* [[SMC protein]]
* [[Cornelia de Lange Syndrome]]
==References==
==References==
{{reflist|2}}
{{Reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{Refbegin | 2}}
{{PBB_Further_reading
*{{cite journal   |vauthors=Nakajima D, Okazaki N, Yamakawa H, etal |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99–106 |year= 2003 |pmid= 12168954 |doi=10.1093/dnares/9.3.99 }}
| citations =
*{{cite journal   |vauthors=Brown CJ, Miller AP, Carrel L, etal |title=The DXS423E gene in Xp11.21 escapes X chromosome inactivation. |journal=Hum. Mol. Genet. |volume=4 |issue= 2 |pages= 251–5 |year= 1995 |pmid= 7757075 |doi=10.1093/hmg/4.2.251 }}
*{{cite journal | author=Nakajima D, Okazaki N, Yamakawa H, ''et al.'' |title=Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. |journal=DNA Res. |volume=9 |issue= 3 |pages= 99-106 |year= 2003 |pmid= 12168954 |doi=  }}
*{{cite journal   |vauthors=Matoba R, Okubo K, Hori N, etal |title=The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression. |journal=Gene |volume=146 |issue= 2 |pages= 199–207 |year= 1994 |pmid= 8076819 |doi=10.1016/0378-1119(94)90293-3 }}
*{{cite journal | author=Rocques PJ, Clark J, Ball S, ''et al.'' |title=The human SB1.8 gene (DXS423E) encodes a putative chromosome segregation protein conserved in lower eukaryotes and prokaryotes. |journal=Hum. Mol. Genet. |volume=4 |issue= 2 |pages= 243-9 |year= 1995 |pmid= 7757074 |doi=  }}
*{{cite journal   |vauthors=Nagase T, Seki N, Ishikawa K, etal |title=Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=3 |issue= 1 |pages= 17–24 |year= 1996 |pmid= 8724849 |doi=10.1093/dnares/3.1.17 }}
*{{cite journal | author=Brown CJ, Miller AP, Carrel L, ''et al.'' |title=The DXS423E gene in Xp11.21 escapes X chromosome inactivation. |journal=Hum. Mol. Genet. |volume=4 |issue= 2 |pages= 251-5 |year= 1995 |pmid= 7757075 |doi=  }}
*{{cite journal  | vauthors=Chen Y, Sharp ZD, Lee WH |title=HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins. |journal=J. Biol. Chem. |volume=272 |issue= 38 |pages= 24081–7 |year= 1997 |pmid= 9295362 |doi=10.1074/jbc.272.38.24081  }}
*{{cite journal | author=Matoba R, Okubo K, Hori N, ''et al.'' |title=The addition of 5'-coding information to a 3'-directed cDNA library improves analysis of gene expression. |journal=Gene |volume=146 |issue= 2 |pages= 199-207 |year= 1994 |pmid= 8076819 |doi=  }}
*{{cite journal   |vauthors=Schmiesing JA, Ball AR, Gregson HC, etal |title=Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 22 |pages= 12906–11 |year= 1998 |pmid= 9789013 |doi=10.1073/pnas.95.22.12906  | pmc=23650  }}
*{{cite journal  | author=Nagase T, Seki N, Ishikawa K, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. |journal=DNA Res. |volume=3 |issue= 1 |pages= 17-24 |year= 1996 |pmid= 8724849 |doi= }}
*{{cite journal  | vauthors=Zheng L, Chen Y, Lee WH |title=Hec1p, an evolutionarily conserved coiled-coil protein, modulates chromosome segregation through interaction with SMC proteins. |journal=Mol. Cell. Biol. |volume=19 |issue= 8 |pages= 5417–28 |year= 1999 |pmid= 10409732 |doi= 10.1128/mcb.19.8.5417| pmc=84384 }}
*{{cite journal | author=Chen Y, Sharp ZD, Lee WH |title=HEC binds to the seventh regulatory subunit of the 26 S proteasome and modulates the proteolysis of mitotic cyclins. |journal=J. Biol. Chem. |volume=272 |issue= 38 |pages= 24081-7 |year= 1997 |pmid= 9295362 |doi= }}
*{{cite journal  | vauthors=Losada A, Yokochi T, Kobayashi R, Hirano T |title=Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes. |journal=J. Cell Biol. |volume=150 |issue= 3 |pages= 405–16 |year= 2000 |pmid= 10931856 |doi=10.1083/jcb.150.3.405  | pmc=2175199 }}
*{{cite journal  | author=Schmiesing JA, Ball AR, Gregson HC, ''et al.'' |title=Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=95 |issue= 22 |pages= 12906-11 |year= 1998 |pmid= 9789013 |doi=  }}
*{{cite journal   |vauthors=Sumara I, Vorlaufer E, Gieffers C, etal |title=Characterization of vertebrate cohesin complexes and their regulation in prophase. |journal=J. Cell Biol. |volume=151 |issue= 4 |pages= 749–62 |year= 2000 |pmid= 11076961 |doi=10.1083/jcb.151.4.749  | pmc=2169443 }}
*{{cite journal  | author=Zheng L, Chen Y, Lee WH |title=Hec1p, an evolutionarily conserved coiled-coil protein, modulates chromosome segregation through interaction with SMC proteins. |journal=Mol. Cell. Biol. |volume=19 |issue= 8 |pages= 5417-28 |year= 1999 |pmid= 10409732 |doi=  }}
*{{cite journal   |vauthors=Revenkova E, Eijpe M, Heyting C, etal |title=Novel meiosis-specific isoform of mammalian SMC1. |journal=Mol. Cell. Biol. |volume=21 |issue= 20 |pages= 6984–98 |year= 2001 |pmid= 11564881 |doi= 10.1128/MCB.21.20.6984-6998.2001 | pmc=99874 }}
*{{cite journal | author=Losada A, Yokochi T, Kobayashi R, Hirano T |title=Identification and characterization of SA/Scc3p subunits in the Xenopus and human cohesin complexes. |journal=J. Cell Biol. |volume=150 |issue= 3 |pages= 405-16 |year= 2000 |pmid= 10931856 |doi=  }}
*{{cite journal   |vauthors=Gregson HC, Schmiesing JA, Kim JS, etal |title=A potential role for human cohesin in mitotic spindle aster assembly. |journal=J. Biol. Chem. |volume=276 |issue= 50 |pages= 47575–82 |year= 2002 |pmid= 11590136 |doi= 10.1074/jbc.M103364200 }}
*{{cite journal | author=Sumara I, Vorlaufer E, Gieffers C, ''et al.'' |title=Characterization of vertebrate cohesin complexes and their regulation in prophase. |journal=J. Cell Biol. |volume=151 |issue= 4 |pages= 749-62 |year= 2000 |pmid= 11076961 |doi=  }}
*{{cite journal   |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9  }}
*{{cite journal | author=Revenkova E, Eijpe M, Heyting C, ''et al.'' |title=Novel meiosis-specific isoform of mammalian SMC1. |journal=Mol. Cell. Biol. |volume=21 |issue= 20 |pages= 6984-98 |year= 2001 |pmid= 11564881 |doi= 10.1128/MCB.21.20.6984-6998.2001 }}
*{{cite journal  | vauthors=Kim ST, Xu B, Kastan MB |title=Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. |journal=Genes Dev. |volume=16 |issue= 5 |pages= 560–70 |year= 2002 |pmid= 11877376 |doi= 10.1101/gad.970602 | pmc=155347 }}
*{{cite journal | author=Gregson HC, Schmiesing JA, Kim JS, ''et al.'' |title=A potential role for human cohesin in mitotic spindle aster assembly. |journal=J. Biol. Chem. |volume=276 |issue= 50 |pages= 47575-82 |year= 2002 |pmid= 11590136 |doi= 10.1074/jbc.M103364200 }}
*{{cite journal   |vauthors=Yazdi PT, Wang Y, Zhao S, etal |title=SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. |journal=Genes Dev. |volume=16 |issue= 5 |pages= 571–82 |year= 2002 |pmid= 11877377 |doi= 10.1101/gad.970702  | pmc=155356 }}
*{{cite journal  | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi=  }}
*{{cite journal   |vauthors=Gregson HC, Van Hooser AA, Ball AR, etal |title=Localization of human SMC1 protein at kinetochores. |journal=Chromosome Res. |volume=10 |issue= 4 |pages= 267–77 |year= 2003 |pmid= 12199140 |doi=10.1023/A:1016563523208  }}
*{{cite journal | author=Kim ST, Xu B, Kastan MB |title=Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. |journal=Genes Dev. |volume=16 |issue= 5 |pages= 560-70 |year= 2002 |pmid= 11877376 |doi= 10.1101/gad.970602 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Yazdi PT, Wang Y, Zhao S, ''et al.'' |title=SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. |journal=Genes Dev. |volume=16 |issue= 5 |pages= 571-82 |year= 2002 |pmid= 11877377 |doi= 10.1101/gad.970702 }}
*{{cite journal   |vauthors=Stewart GS, Wang B, Bignell CR, etal |title=MDC1 is a mediator of the mammalian DNA damage checkpoint. |journal=Nature |volume=421 |issue= 6926 |pages= 961–6 |year= 2003 |pmid= 12607005 |doi= 10.1038/nature01446 }}
*{{cite journal | author=Gregson HC, Van Hooser AA, Ball AR, ''et al.'' |title=Localization of human SMC1 protein at kinetochores. |journal=Chromosome Res. |volume=10 |issue= 4 |pages= 267-77 |year= 2003 |pmid= 12199140 |doi=  }}
*{{cite journal  | vauthors=Wang Y, Qin J |title=MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 26 |pages= 15387–92 |year= 2004 |pmid= 14657349 |doi= 10.1073/pnas.2536810100  | pmc=307577 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
{{Refend}}
*{{cite journal  | author=Stewart GS, Wang B, Bignell CR, ''et al.'' |title=MDC1 is a mediator of the mammalian DNA damage checkpoint. |journal=Nature |volume=421 |issue= 6926 |pages= 961-6 |year= 2003 |pmid= 12607005 |doi= 10.1038/nature01446 }}
 
*{{cite journal  | author=Wang Y, Qin J |title=MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=100 |issue= 26 |pages= 15387-92 |year= 2004 |pmid= 14657349 |doi= 10.1073/pnas.2536810100 }}
==External links==
}}
* [https://www.ncbi.nlm.nih.gov/books/NBK1104/  GeneReviews/NCBI/UW/NIH entry on Cornelia de Lange Syndrome]
{{refend}}
 
{{Nucleus}}
 


{{protein-stub}}
{{Gene-X-stub}}
{{WikiDoc Sources}}

Revision as of 20:51, 8 November 2017

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

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Ensembl

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UniProt

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RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
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Wikidata
View/Edit Human

Structural maintenance of chromosomes protein 1A is a protein that in humans is encoded by the SMC1A gene.[1][2]

Function

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation.[2]

Interactions

SMC1A has been shown to interact with SMC3[3][4][5][6] and Ataxia telangiectasia mutated.[3]

See also

References

  1. ↑ Rocques PJ, Clark J, Ball S, Crew J, Gill S, Christodoulou Z, Borts RH, Louis EJ, Davies KE, Cooper CS (June 1995). "The human SB1.8 gene (DXS423E) encodes a putative chromosome segregation protein conserved in lower eukaryotes and prokaryotes". Hum Mol Genet. 4 (2): 243–9. doi:10.1093/hmg/4.2.243. PMID 7757074.
  2. ↑ 2.0 2.1 "Entrez Gene: SMC1A structural maintenance of chromosomes 1A".
  3. ↑ 3.0 3.1 Kim ST, Xu B, Kastan MB (March 2002). "Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage". Genes Dev. 16 (5): 560–70. doi:10.1101/gad.970602. PMC 155347. PMID 11877376.
  4. ↑ Lee J, Iwai T, Yokota T, Yamashita M (July 2003). "Temporally and spatially selective loss of Rec8 protein from meiotic chromosomes during mammalian meiosis". J. Cell Sci. 116 (Pt 13): 2781–90. doi:10.1242/jcs.00495. PMID 12759374.
  5. ↑ Schmiesing JA, Ball AR, Gregson HC, Alderton JM, Zhou S, Yokomori K (October 1998). "Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics". Proc. Natl. Acad. Sci. U.S.A. 95 (22): 12906–11. doi:10.1073/pnas.95.22.12906. PMC 23650. PMID 9789013.
  6. ↑ Gregson HC, Schmiesing JA, Kim JS, Kobayashi T, Zhou S, Yokomori K (December 2001). "A potential role for human cohesin in mitotic spindle aster assembly". J. Biol. Chem. 276 (50): 47575–82. doi:10.1074/jbc.M103364200. PMID 11590136.

Further reading

External links


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