Lactose intolerance laboratory findings: Difference between revisions
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*Laboratory findings consistent with the diagnosis of lactose intolerance include:<ref name="pmid26578625">{{cite journal |vauthors=Kvissberg MA, Dalvi PS, Kerac M, Voskuijl W, Berkley JA, Priebe MG, Bandsma RH |title=Carbohydrate malabsorption in acutely malnourished children and infants: a systematic review |journal=Nutr. Rev. |volume=74 |issue=1 |pages=48–58 |year=2016 |pmid=26578625 |pmc=4684688 |doi=10.1093/nutrit/nuv058 |url=}}</ref> | *Laboratory findings consistent with the diagnosis of lactose intolerance include:<ref name="pmid26578625">{{cite journal |vauthors=Kvissberg MA, Dalvi PS, Kerac M, Voskuijl W, Berkley JA, Priebe MG, Bandsma RH |title=Carbohydrate malabsorption in acutely malnourished children and infants: a systematic review |journal=Nutr. Rev. |volume=74 |issue=1 |pages=48–58 |year=2016 |pmid=26578625 |pmc=4684688 |doi=10.1093/nutrit/nuv058 |url=}}</ref> | ||
**Stool osmotic gap of >125 mOsm/kg due to unabsorbed [[Carbohydrate|carbohydrates]]. | **Stool osmotic gap of >125 mOsm/kg due to unabsorbed [[Carbohydrate|carbohydrates]]. | ||
***Stool osmotic gap: | ***Normal Stool osmotic gap: −290 [(Na+K) × 2] | ||
** Stool [[pH]] <6 due to bacterial [[Fermentation (biochemistry)|fermentation]] of unabsorbed [[lactose]] to [[hydrogen]] gas in the [[Colon (anatomy)|colon]]. | ** Stool [[pH]] <6 due to bacterial [[Fermentation (biochemistry)|fermentation]] of unabsorbed [[lactose]] to [[hydrogen]] gas in the [[Colon (anatomy)|colon]]. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahda Alihashemi M.D. [2]
Overview
Laboratory findings consistent with the diagnosis of lactose intolerance include stool osmotic gap of >125 mOsm/kg, stool pH <6.
Laboratory Findings
- Laboratory findings consistent with the diagnosis of lactose intolerance include:[1]
- Stool osmotic gap of >125 mOsm/kg due to unabsorbed carbohydrates.
- Normal Stool osmotic gap: −290 [(Na+K) × 2]
- Stool pH <6 due to bacterial fermentation of unabsorbed lactose to hydrogen gas in the colon.
- Stool osmotic gap of >125 mOsm/kg due to unabsorbed carbohydrates.
References
- ↑ Kvissberg MA, Dalvi PS, Kerac M, Voskuijl W, Berkley JA, Priebe MG, Bandsma RH (2016). "Carbohydrate malabsorption in acutely malnourished children and infants: a systematic review". Nutr. Rev. 74 (1): 48–58. doi:10.1093/nutrit/nuv058. PMC 4684688. PMID 26578625.