Hepatocellular carcinoma physical examination: Difference between revisions
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===Skin=== | ===Skin=== | ||
*[[Jaundice]] | *[[Jaundice]] : yellow discoloration of the skin, eyes, and mucus membranes due to increased [[bilirubin]] (at least 2-3 mg/dL or 30 mmol/L). [[Urine]] may also appear dark. | ||
*[[ | *[[Pallor]] | ||
* | *[[Bruise|Bruises]] | ||
*Peripheral [[Edema]] | *Peripheral [[Edema]] | ||
*[[Palmar erythema]] on the [[Thenar eminence|thenar]] and [[Hypothenar eminence|hypothenar eminences]], due to altered sex hormone metabolism. | |||
*[[Spider angioma|Spider angiomata]]: Increased estradiol levels lead to the formation of vascular lesions consisting of central arterioles surrounded by smaller vessels <ref name="pmid10423070">{{cite journal |author=Li CP, Lee FY, Hwang SJ, ''et al'' |title=Spider angiomas in patients with liver cirrhosis: role of alcoholism and impaired liver function|journal=Scand. J. Gastroenterol. |volume=34 |issue=5 |pages=520-3 |year=1999 |pmid=10423070 |doi=}}</ref> | |||
*'''[[Telangiectasia|Telangiectasias]]''' or '''spider veins:''' small dilated [[blood vessel]]s near the surface of the [[skin]]. | |||
<gallery widths="250px"> | |||
Telingectasia1.jpg||thumb|200px|Telingectasias <br> Source: Wikimedia commons | |||
Image:Palmar erythema 1.jpg|thumb|Palmar erythema <br> Source: Wikimedia commons<ref name="urlFile:Kawasaki symptoms D.jpg - Wikimedia Commons">{{cite web |url=https://commons.wikimedia.org/wiki/File:Kawasaki_symptoms_D.jpg |title=File:Kawasaki symptoms D.jpg - Wikimedia Commons |format= |work= |accessdate=}}</ref> | |||
===Eyes=== | ===Eyes=== |
Revision as of 15:45, 5 January 2018
Hepatocellular carcinoma Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Dildar Hussain, MBBS [2]
Overview
Patients with hepatocellular carcinoma usually appear cachectic. Physical examination of patients with hepatocellular carcinoma is usually remarkable for jaundice, pruritus, ascites, splenomegaly, esophageal varices, and cachexia.
Physical Examination
Common physical examination findings of hepatocellular carcinoma are:
Appearance of the Patient
- The general appearance of the patient depends on the severity of the disease:
- The patient is often cachexic
- May appear anxious.
- Dyspnea if ascites is present
Vitals
Temperature
- Fever is usually present in advanced cases
Skin
- Jaundice : yellow discoloration of the skin, eyes, and mucus membranes due to increased bilirubin (at least 2-3 mg/dL or 30 mmol/L). Urine may also appear dark.
- Pallor
- Bruises
- Peripheral Edema
- Palmar erythema on the thenar and hypothenar eminences, due to altered sex hormone metabolism.
- Spider angiomata: Increased estradiol levels lead to the formation of vascular lesions consisting of central arterioles surrounded by smaller vessels [1]
- Telangiectasias or spider veins: small dilated blood vessels near the surface of the skin.
<gallery widths="250px">
Telingectasia1.jpg||thumb|200px|Telingectasias
Source: Wikimedia commons
Image:Palmar erythema 1.jpg|thumb|Palmar erythema
Source: Wikimedia commons[2]
Eyes
Icteric sclera
Lungs
- The signs of pleural effusion are noted in advanced disease
Abdomen
Significant abdominal findings are seen in advanced stages
- Hepatomegaly
- Splenomegaly
- Ascites
- Abdominal distention may be present
- Abdominal tenderness may be present
References
- ↑ Li CP, Lee FY, Hwang SJ; et al. (1999). "Spider angiomas in patients with liver cirrhosis: role of alcoholism and impaired liver function". Scand. J. Gastroenterol. 34 (5): 520–3. PMID 10423070.
- ↑ "File:Kawasaki symptoms D.jpg - Wikimedia Commons".