Alpha 1-antitrypsin deficiency x ray: Difference between revisions
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==X Ray== | ==X Ray== | ||
On [[chest X-ray]] alpha1-antitrypsin deficiency (AATD) [[emphysema]] presents as:<ref name="pmid8633137">{{cite journal |vauthors=King MA, Stone JA, Diaz PT, Mueller CF, Becker WJ, Gadek JE |title=Alpha 1-antitrypsin deficiency: evaluation of bronchiectasis with CT |journal=Radiology |volume=199 |issue=1 |pages=137–41 |year=1996 |pmid=8633137 |doi=10.1148/radiology.199.1.8633137 |url=}}</ref><ref name="pmid15306534">{{cite journal |vauthors=Parr DG, Stoel BC, Stolk J, Stockley RA |title=Pattern of emphysema distribution in alpha1-antitrypsin deficiency influences lung function impairment |journal=Am. J. Respir. Crit. Care Med. |volume=170 |issue=11 |pages=1172–8 |year=2004 |pmid=15306534 |doi=10.1164/rccm.200406-761OC |url=}}</ref> | On [[chest X-ray]] alpha1-antitrypsin deficiency (AATD) [[emphysema]] presents as:<ref name="pmid8633137">{{cite journal |vauthors=King MA, Stone JA, Diaz PT, Mueller CF, Becker WJ, Gadek JE |title=Alpha 1-antitrypsin deficiency: evaluation of bronchiectasis with CT |journal=Radiology |volume=199 |issue=1 |pages=137–41 |year=1996 |pmid=8633137 |doi=10.1148/radiology.199.1.8633137 |url=}}</ref><ref name="pmid15306534">{{cite journal |vauthors=Parr DG, Stoel BC, Stolk J, Stockley RA |title=Pattern of emphysema distribution in alpha1-antitrypsin deficiency influences lung function impairment |journal=Am. J. Respir. Crit. Care Med. |volume=170 |issue=11 |pages=1172–8 |year=2004 |pmid=15306534 |doi=10.1164/rccm.200406-761OC |url=}}</ref> | ||
*A hyperlucent appearance because healthy tissue has been destroyed. | *A hyperlucent appearance because [[Tissue (anatomy)|healthy tissue]] has been destroyed. | ||
*Affected regions also are described as oligemic because they lack the normal rich pattern of branching blood vessels. | *Affected regions also are described as oligemic because they lack the normal rich pattern of [[Blood vessel|branching blood vessels]]. | ||
*An unusual characteristic in alpha1-antitrypsin deficiency is found in about 60% of PiZZ is that [[emphysema]] has a striking basilar distribution | *An unusual characteristic in alpha1-antitrypsin deficiency is found in about 60% of PiZZ is that [[emphysema]] has a striking basilar distribution | ||
*In contrast, [[cigarette smoking]] is associated with more severe apical [[disease]]. | *In contrast, [[cigarette smoking]] is associated with more severe apical [[disease]]. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
On chest X-ray alpha1-antitrypsin deficiency (AATD) emphysema presents as a hyperlucent appearance because healthy tissue has been destroyed. Affected regions also are described as oligemic because they lack the normal rich pattern of branching blood vessels. An unusual characteristic in alpha1-antitrypsin deficiency is found in about 60% of PiZZ patients is the striking basilar distribution. In contrast, cigarette smoking is associated with more severe apical disease.
X Ray
On chest X-ray alpha1-antitrypsin deficiency (AATD) emphysema presents as:[1][2]
- A hyperlucent appearance because healthy tissue has been destroyed.
- Affected regions also are described as oligemic because they lack the normal rich pattern of branching blood vessels.
- An unusual characteristic in alpha1-antitrypsin deficiency is found in about 60% of PiZZ is that emphysema has a striking basilar distribution
- In contrast, cigarette smoking is associated with more severe apical disease.
References
- ↑ King MA, Stone JA, Diaz PT, Mueller CF, Becker WJ, Gadek JE (1996). "Alpha 1-antitrypsin deficiency: evaluation of bronchiectasis with CT". Radiology. 199 (1): 137–41. doi:10.1148/radiology.199.1.8633137. PMID 8633137.
- ↑ Parr DG, Stoel BC, Stolk J, Stockley RA (2004). "Pattern of emphysema distribution in alpha1-antitrypsin deficiency influences lung function impairment". Am. J. Respir. Crit. Care Med. 170 (11): 1172–8. doi:10.1164/rccm.200406-761OC. PMID 15306534.