Barrett's esophagus natural history, complications and prognosis: Difference between revisions
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==Overview== | ==Overview== | ||
Common complications of [[Barrett's esophagus]] include [[esophageal carcinoma]], [[esophageal stricture]] | Common complications of [[Barrett's esophagus]] include [[esophageal carcinoma]], [[esophageal stricture]] and [[esophageal]] [[ulcers]]<ref name="pmid22826612">{{cite journal| author=Milind R, Attwood SE| title=Natural history of Barrett's esophagus. | journal=World J Gastroenterol | year= 2012 | volume= 18 | issue= 27 | pages= 3483-91 | pmid=22826612 | doi=10.3748/wjg.v18.i27.3483 | pmc=3400849 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22826612 }} </ref>. | ||
==Natural History, Complications, and Prognosis== | ==Natural History, Complications, and Prognosis== | ||
Revision as of 15:47, 2 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Amresh Kumar MD [2]
Overview
Common complications of Barrett's esophagus include esophageal carcinoma, esophageal stricture and esophageal ulcers[1].
Natural History, Complications, and Prognosis
Natural History
An increased risk of esophageal cancer. Follow-up endoscopy to look for dysplasia or cancer is often advised.
- The symptoms of Barrett's esophagus usually develop in the fifth/sixth decade of life, and start with symptoms of GERD such as heartburn, regurgitation and dysphagia.
- The symptoms of (disease name) typically develop ___ years after exposure to ___.
- If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
Complications
- Common complications of Barrett's esophagus include:
Progression
- From low-grade dysplasia to high-grade dysplasia or esophageal adenocarcinoma: 0.5 to 13.4% per year
- From high-grade dysplasia to cancer: 6% per year.[3]
Prognosis
- Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
- Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
- The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
- [Subtype of disease/malignancy] is associated with the most favorable prognosis.
- The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.
References
- ↑ Milind R, Attwood SE (2012). "Natural history of Barrett's esophagus". World J Gastroenterol. 18 (27): 3483–91. doi:10.3748/wjg.v18.i27.3483. PMC 3400849. PMID 22826612.
- ↑ Hvid-Jensen F, Pedersen L, Drewes AM, Sørensen HT, Funch-Jensen P (2011). "Incidence of adenocarcinoma among patients with Barrett's esophagus". N Engl J Med. 365 (15): 1375–83. doi:10.1056/NEJMoa1103042. PMID 21995385.
- ↑ Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ (2011). "American Gastroenterological Association medical position statement on the management of Barrett's esophagus". Gastroenterology. 140 (3): 1084–91. doi:10.1053/j.gastro.2011.01.030. PMID 21376940. Unknown parameter
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