Occupational lung disease laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

There are no diagnostic laboratory findings associated with occupational lung disease. However, useful laboratory findings consistent with the diagnosis of occupational lung disease include abnormal arterial blood gases, sputum analysis, and blood picture.

Laboratory Findings

• Laboratory findings consistent with the diagnosis of occupational lung disease include:
  • Abnormal ABG
    • May indicate hypoxia, hypercapnia and respiratory acidosis
  • Abnormal sputum analysis
    • May contain bacteria or inorganic or organic particles
  • Peak flow assessment
    • May be below normal range which is 100 liters/minute for men, and 80 liters/minute for women
  • Spirometry
    • May indicate an obstructive or restrictive pulmonary disease
    • A FEV1/FVC ratio < 80% indicates and obstructive disease,such as asthma, whilst a FEV1/FVC ratio higher than restrictive pulmonary disease indicates a restrictive disease, such as pulmonary fibrosis
  • CBC
    • May indicate anemia