Atelectasis causes: Difference between revisions

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==Overview==
==Overview==
The most common cause is post-surgical atelectasis, characterized by splinting, restricted breathing after abdominal surgery. Outside of this context, atelectasis implies some blockage of a [[bronchiole]] or [[bronchus]], which can be within the airway (foreign body, mucus plug), from the wall (tumor, usually [[squamous cell carcinoma]]) or compressing from the outside ([[tumor]], [[lymph node]], [[Tuberculosis|tubercle]]). Another cause is poor [[pulmonary surfactant|surfactant]] spreading during [[Inhalation|inspiration]], causing an increase in [[surface tension]] which tends to collapse smaller alveoli.
The most common cause of atelectasis is postoperative atelectasis, due to the effect of surgical manipulation or [[general anaesthesia]] on the patient. Obstructive atelectasis mostly develops due to blockage within the [[bronchiole]] or [[bronchus]], which may be within the airway (foreign bodies, mucus plugs), arising from the wall (tumors such as [[squamous cell carcinoma]]) or space occupying lesions within the thoracic cavity ([[tumor]], [[lymph node]], [[Tuberculosis|tubercle]]). Causes of non obstructive atelectasis include impaired [[pulmonary surfactant|surfactant]] formation or activation, leading to alveolar collapse due to increased surface tension.
==Causes==
==Causes==
[[Atelectasis]] may arise due to [[Obstruction|obstructive]] and non-obstructive causes.  
[[Atelectasis]] may arise due to [[Obstruction|obstructive]] and non-obstructive causes.  
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** Diminished levels of [[Pulmonary surfactant|surfactant]]: Adhesive atelectasis presenting as [[Acute respiratory distress syndrome|ARDS]]
** Diminished levels of [[Pulmonary surfactant|surfactant]]: Adhesive atelectasis presenting as [[Acute respiratory distress syndrome|ARDS]]
** Absence of contact between the [[Parietal pleura|parietal]] and [[Visceral pleura|visceral pleurae]] due to fluid ([[pleural effusion]]), air ([[pneumothorax]]), blood ([[hemothorax]]): Passive atelectasis  
** Absence of contact between the [[Parietal pleura|parietal]] and [[Visceral pleura|visceral pleurae]] due to fluid ([[pleural effusion]]), air ([[pneumothorax]]), blood ([[hemothorax]]): Passive atelectasis  
* Atelectasis of the upper lobe commonly occurs due to [[pneumothorax]], whereas atelectasis of the middle and lower lobes occurs due to [[pleural effusion]].
** Formation of fibrous bands which adhere the [[lung]] to the [[Pleural cavity|pleura]] in patients with [[asbestosis]]: Rounded atelectasis
 
** Complication of [[surgery]] or [[Anesthesia|anaesthesia]] leading to decreased surfactant activity and dysfunction of the [[Thoracic diaphragm|diaphragm]]: Postoperative atelectasis
* Formation of fibrous bands which adhere the [[lung]] to the [[Pleural cavity|pleura]] in patients with [[asbestosis]]: Rounded atelectasis  


===Common Causes===
===Common Causes===
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* [[Anesthesia]]
* [[Anesthesia]]
* Foreign bodies
* Foreign bodies
* [[Lung Disease]]
* [[Lung Disease]]: [[Pulmonary embolism]], [[Lower respiratory tract infection|lower respiratory tract infections]]
* [[Mucus]] Plug
* [[Mucus]] Plug
* [[Pleural Effusion]]
* [[Pleural Effusion]]
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* [[Pneumonia]]
* [[Pneumonia]]
* [[Pneumothorax]]
* [[Pneumothorax]]
* Scarring of Lung Tissue
* Scarring of lung parenchyma
* [[Acetaminophen]]
* [[Acetaminophen]]
* [[Follitropin beta]]
* [[Follitropin beta]]

Revision as of 15:05, 15 February 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Somal Khan, M.D., Jacquelyne DiTroia

Overview

The most common cause of atelectasis is postoperative atelectasis, due to the effect of surgical manipulation or general anaesthesia on the patient. Obstructive atelectasis mostly develops due to blockage within the bronchiole or bronchus, which may be within the airway (foreign bodies, mucus plugs), arising from the wall (tumors such as squamous cell carcinoma) or space occupying lesions within the thoracic cavity (tumor, lymph node, tubercle). Causes of non obstructive atelectasis include impaired surfactant formation or activation, leading to alveolar collapse due to increased surface tension.

Causes

Atelectasis may arise due to obstructive and non-obstructive causes.

Obstructive atelectasis

  • Obstructive atelectasis, which is the most common type of atelectasis may develop due to obstruction by foreign bodies, tumors and mucus plugs. In case of obstruction from the trachea to the alveoli at any level, alveolar gas reabsorption may occur leading to subsequent atelectasis.
  • Middle lobe syndrome (fixed or recurrent atelectasis of the lingula/ right middle lobe) may occur due to Sjogren’s syndrome. Intraluminal or extraluminal obstruction (compression of the bronchi by adjacent structures) may result in middle lobe syndrome.

Non-obstructive atelectasis

Common Causes

The most common causes of Atelectasis are:

Causes by Organ System

Cardiovascular No underlying causes
Chemical / poisoning No underlying causes
Dermatologic No underlying causes
Drug Side Effect Anesthesia, Acetaminophen, Follitropin beta, Urofollitropin
Ear Nose Throat Mucus Plug
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic Blood clot
Iatrogenic No underlying causes
Infectious Disease No underlying causes
Musculoskeletal / Ortho No underlying causes
Neurologic No underlying causes
Nutritional / Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Tumors
Opthalmologic No underlying causes
Overdose / Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Lung Disease, Pleural Effusion, Pneumonia, Pneumothorax, Scarring of Lung Tissue
Renal / Electrolyte No underlying causes
Rheum / Immune / Allergy No underlying causes
Sexual No underlying causes
Trauma Chest Trauma
Urologic No underlying causes
Dental No underlying causes
Miscellaneous Foreign object in the airway

Causes in Alphabetical Order


References

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