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== Epidemiology of syphilis and tabes dorsalis == | == Epidemiology of syphilis and tabes dorsalis == | ||
Tabes dorsalis is now very rare because [[syphilis]] is usually treated early in the disease. | Tabes dorsalis is now very rare because [[syphilis]] is usually treated early in the disease. | ||
* In 2012, the [[incidence]] of [[syphilis]] was estimated to be 6 million cases worldwide. | |||
In 2012, the [[incidence]] of [[syphilis]] was estimated to be 6 million cases worldwide. From year 2005 to 2014, the [[incidence]] of [[syphilis]] in the United States increased from 2.9 to 6.3 cases/100,000/year. The rate of reported cases increased by 15.1% between 2013 and 2014 in the United States.<ref name="CDC">https://www.cdc.gov/std/stats14/surv-2014-print.pdf Accessed on September 16, 2016</ref> [[Syphilis]] incidence increased in every region of the Untied States in 2014, with the highest rate in the West and lowest rate in the Midwest. In 2012, the [[prevalence]] of [[syphilis]] was estimated to be approximately 18 million cases in men and women aged 15-29 worldwide.<ref name="pmid26646541">{{cite journal| author=Newman L, Rowley J, Vander Hoorn S, Wijesooriya NS, Unemo M, Low N et al.| title=Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting. | journal=PLoS One | year= 2015 | volume= 10 | issue= 12 | pages= e0143304 | pmid=26646541 | doi=10.1371/journal.pone.0143304 | pmc=4672879 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26646541 }} </ref> The [[incidence]] and [[prevalence]] of [[syphilis]] may be affected by age, gender, race, sexual behavior and geographical distribution. Among infected patients with [[Treponema pallidum]] only 3 to 5% develop [[neurosyphilis]] and only 5% of those individuals develop tabes dorsalis, 10–20 years later.<ref name="CDC">https://www.cdc.gov/std/stats14/surv-2014-print.pdf Accessed on September 16, 2016</ref><ref name="pmid23403598">{{cite journal| author=Satterwhite CL, Torrone E, Meites E, Dunne EF, Mahajan R, Ocfemia MC et al.| title=Sexually transmitted infections among US women and men: prevalence and incidence estimates, 2008. | journal=Sex Transm Dis | year= 2013 | volume= 40 | issue= 3 | pages= 187-93 | pmid=23403598 | doi=10.1097/OLQ.0b013e318286bb53 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23403598 }} </ref><ref name="WHO2012">http://apps.who.int/iris/bitstream/10665/85376/1/9789241505895_eng.pdf?=1 Accessed on September 16, 2016</ref><ref name="pmid23049658">{{cite journal| author=Purcell DW, Johnson CH, Lansky A, Prejean J, Stein R, Denning P et al.| title=Estimating the population size of men who have sex with men in the United States to obtain HIV and syphilis rates. | journal=Open AIDS J | year= 2012 | volume= 6 | issue= | pages= 98-107 | pmid=23049658 | doi=10.2174/1874613601206010098 | pmc=3462414 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23049658 }} </ref><ref name="pmid17463387">{{cite journal| author=Heffelfinger JD, Swint EB, Berman SM, Weinstock HS| title=Trends in primary and secondary syphilis among men who have sex with men in the United States. | journal=Am J Public Health | year= 2007 | volume= 97 | issue= 6 | pages= 1076-83 | pmid=17463387 | doi=10.2105/AJPH.2005.070417 | pmc=1874206 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17463387 }} </ref><ref name="pmid6893897">{{cite journal| author=Judson FN, Penley KA, Robinson ME, Smith JK| title=Comparative prevalence rates of sexually transmitted diseases in heterosexual and homosexual men. | journal=Am J Epidemiol | year= 1980 | volume= 112 | issue= 6 | pages= 836-43 | pmid=6893897 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6893897 }} </ref><ref name="pmid22330117">{{cite journal| author=Pandey S| title=Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. | journal=J Spinal Cord Med | year= 2011 | volume= 34 | issue= 6 | pages= 609-11 | pmid=22330117 | doi=10.1179/2045772311Y.0000000041 | pmc=3237288 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22330117 }} </ref> | * From year 2005 to 2014, the [[incidence]] of [[syphilis]] in the United States increased from 2.9 to 6.3 cases/100,000/year. | ||
* The rate of reported cases increased by 15.1% between 2013 and 2014 in the United States.<ref name="CDC">https://www.cdc.gov/std/stats14/surv-2014-print.pdf Accessed on September 16, 2016</ref> | |||
* [[Syphilis]] incidence increased in every region of the Untied States in 2014, with the highest rate in the West and lowest rate in the Midwest. | |||
* In 2012, the [[prevalence]] of [[syphilis]] was estimated to be approximately 18 million cases in men and women aged 15-29 worldwide.<ref name="pmid26646541">{{cite journal| author=Newman L, Rowley J, Vander Hoorn S, Wijesooriya NS, Unemo M, Low N et al.| title=Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting. | journal=PLoS One | year= 2015 | volume= 10 | issue= 12 | pages= e0143304 | pmid=26646541 | doi=10.1371/journal.pone.0143304 | pmc=4672879 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26646541 }} </ref> | |||
* The [[incidence]] and [[prevalence]] of [[syphilis]] may be affected by age, gender, race, sexual behavior and geographical distribution. | |||
* Among infected patients with [[Treponema pallidum]] only 3 to 5% develop [[neurosyphilis]] and only 5% of those individuals develop tabes dorsalis, 10–20 years later.<ref name="CDC">https://www.cdc.gov/std/stats14/surv-2014-print.pdf Accessed on September 16, 2016</ref><ref name="pmid23403598">{{cite journal| author=Satterwhite CL, Torrone E, Meites E, Dunne EF, Mahajan R, Ocfemia MC et al.| title=Sexually transmitted infections among US women and men: prevalence and incidence estimates, 2008. | journal=Sex Transm Dis | year= 2013 | volume= 40 | issue= 3 | pages= 187-93 | pmid=23403598 | doi=10.1097/OLQ.0b013e318286bb53 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23403598 }} </ref><ref name="WHO2012">http://apps.who.int/iris/bitstream/10665/85376/1/9789241505895_eng.pdf?=1 Accessed on September 16, 2016</ref><ref name="pmid23049658">{{cite journal| author=Purcell DW, Johnson CH, Lansky A, Prejean J, Stein R, Denning P et al.| title=Estimating the population size of men who have sex with men in the United States to obtain HIV and syphilis rates. | journal=Open AIDS J | year= 2012 | volume= 6 | issue= | pages= 98-107 | pmid=23049658 | doi=10.2174/1874613601206010098 | pmc=3462414 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23049658 }} </ref><ref name="pmid17463387">{{cite journal| author=Heffelfinger JD, Swint EB, Berman SM, Weinstock HS| title=Trends in primary and secondary syphilis among men who have sex with men in the United States. | journal=Am J Public Health | year= 2007 | volume= 97 | issue= 6 | pages= 1076-83 | pmid=17463387 | doi=10.2105/AJPH.2005.070417 | pmc=1874206 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17463387 }} </ref><ref name="pmid6893897">{{cite journal| author=Judson FN, Penley KA, Robinson ME, Smith JK| title=Comparative prevalence rates of sexually transmitted diseases in heterosexual and homosexual men. | journal=Am J Epidemiol | year= 1980 | volume= 112 | issue= 6 | pages= 836-43 | pmid=6893897 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6893897 }} </ref><ref name="pmid22330117">{{cite journal| author=Pandey S| title=Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis. | journal=J Spinal Cord Med | year= 2011 | volume= 34 | issue= 6 | pages= 609-11 | pmid=22330117 | doi=10.1179/2045772311Y.0000000041 | pmc=3237288 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22330117 }} </ref> | |||
==References== | ==References== | ||
Revision as of 14:58, 16 February 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Mohamadmostafa Jahansouz M.D.[2] Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[3]; Nate Michalak, B.A.
Overview
Tabes dorsalis is now very rare because syphilis is usually treated early in the disease.
In 2012, the incidence of syphilis was estimated to be 6 million cases worldwide. From year 2005 to 2014, the incidence of syphilis in the United States increased from 2.9 to 6.3 cases/100,000/year. The rate of reported cases increased by 15.1% between 2013 and 2014 in the United States. In 2012, the prevalence of syphilis was estimated to be approximately 18 million cases in men and women aged 15-29 worldwide. Among infected patients with Treponema pallidum only 3 to 5% develop neurosyphilis and only 5% of those individuals develop tabes dorsalis, 10–20 years later.
Epidemiology of syphilis and tabes dorsalis
Tabes dorsalis is now very rare because syphilis is usually treated early in the disease.
- In 2012, the incidence of syphilis was estimated to be 6 million cases worldwide.
- From year 2005 to 2014, the incidence of syphilis in the United States increased from 2.9 to 6.3 cases/100,000/year.
- The rate of reported cases increased by 15.1% between 2013 and 2014 in the United States.[1]
- Syphilis incidence increased in every region of the Untied States in 2014, with the highest rate in the West and lowest rate in the Midwest.
- In 2012, the prevalence of syphilis was estimated to be approximately 18 million cases in men and women aged 15-29 worldwide.[2]
- The incidence and prevalence of syphilis may be affected by age, gender, race, sexual behavior and geographical distribution.
- Among infected patients with Treponema pallidum only 3 to 5% develop neurosyphilis and only 5% of those individuals develop tabes dorsalis, 10–20 years later.[1][3][4][5][6][7][8]
References
- ↑ 1.0 1.1 https://www.cdc.gov/std/stats14/surv-2014-print.pdf Accessed on September 16, 2016
- ↑ Newman L, Rowley J, Vander Hoorn S, Wijesooriya NS, Unemo M, Low N; et al. (2015). "Global Estimates of the Prevalence and Incidence of Four Curable Sexually Transmitted Infections in 2012 Based on Systematic Review and Global Reporting". PLoS One. 10 (12): e0143304. doi:10.1371/journal.pone.0143304. PMC 4672879. PMID 26646541.
- ↑ Satterwhite CL, Torrone E, Meites E, Dunne EF, Mahajan R, Ocfemia MC; et al. (2013). "Sexually transmitted infections among US women and men: prevalence and incidence estimates, 2008". Sex Transm Dis. 40 (3): 187–93. doi:10.1097/OLQ.0b013e318286bb53. PMID 23403598.
- ↑ http://apps.who.int/iris/bitstream/10665/85376/1/9789241505895_eng.pdf?=1 Accessed on September 16, 2016
- ↑ Purcell DW, Johnson CH, Lansky A, Prejean J, Stein R, Denning P; et al. (2012). "Estimating the population size of men who have sex with men in the United States to obtain HIV and syphilis rates". Open AIDS J. 6: 98–107. doi:10.2174/1874613601206010098. PMC 3462414. PMID 23049658.
- ↑ Heffelfinger JD, Swint EB, Berman SM, Weinstock HS (2007). "Trends in primary and secondary syphilis among men who have sex with men in the United States". Am J Public Health. 97 (6): 1076–83. doi:10.2105/AJPH.2005.070417. PMC 1874206. PMID 17463387.
- ↑ Judson FN, Penley KA, Robinson ME, Smith JK (1980). "Comparative prevalence rates of sexually transmitted diseases in heterosexual and homosexual men". Am J Epidemiol. 112 (6): 836–43. PMID 6893897.
- ↑ Pandey S (2011). "Magnetic resonance imaging of the spinal cord in a man with tabes dorsalis". J Spinal Cord Med. 34 (6): 609–11. doi:10.1179/2045772311Y.0000000041. PMC 3237288. PMID 22330117.