Occupational lung disease medical therapy: Difference between revisions
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** 1.1 '''Glucocorticoids''' | ** 1.1 '''Glucocorticoids''' | ||
*** 1.1.1 '''Adult''' | *** 1.1.1 '''Adult''' | ||
**** Preferred regimen (1): Prednisolone or Prednisone 0.5 - 0.6 mg/kg q12h for 6 - 12 weeks | **** Preferred regimen (1): Prednisolone or Prednisone 0.5 - 0.6 mg/kg q12h for 6 - 12 weeks<ref name="pmid18757698">{{cite journal |vauthors=Marchand-Adam S, El Khatib A, Guillon F, Brauner MW, Lamberto C, Lepage V, Naccache JM, Valeyre D |title=Short- and long-term response to corticosteroid therapy in chronic beryllium disease |journal=Eur. Respir. J. |volume=32 |issue=3 |pages=687–93 |year=2008 |pmid=18757698 |doi=10.1183/09031936.00149607 |url=}}</ref><ref name="pmid15596705">{{cite journal |vauthors=Sood A, Beckett WS, Cullen MR |title=Variable response to long-term corticosteroid therapy in chronic beryllium disease |journal=Chest |volume=126 |issue=6 |pages=2000–7 |year=2004 |pmid=15596705 |doi=10.1378/chest.126.6.2000 |url=}}</ref> | ||
***: '''Note (1):''' Taper down to 20mg after clinical improvement of DLCO, arterial blood gases, and pulse oxygen saturation. Followed by 40mg on alternate days. Finally, 5 - 10mg q12h. | ***: '''Note (1):''' Taper down to 20mg after clinical improvement of DLCO, arterial blood gases, and pulse oxygen saturation. Followed by 40mg on alternate days. Finally, 5 - 10mg q12h. | ||
==References== | ==References== | ||
Revision as of 16:56, 19 February 2018
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Occupational lung disease Microchapters |
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Differentiating Occupational lung disease from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]
Overview
Supportive therapy for occupational lung disease before fibrotic disease sets in includes glucocorticoid therapy.
Medical Therapy
Pharmacologic medical therapy such as glucocorticoid is recommended among patients without fibrotic lung disease to decelerate lung disease progression and to improve lung function.
Occupational lung disease
- 1 Prefibrotic stage of lung disease
- 1.1 Glucocorticoids
References
- ↑ Marchand-Adam S, El Khatib A, Guillon F, Brauner MW, Lamberto C, Lepage V, Naccache JM, Valeyre D (2008). "Short- and long-term response to corticosteroid therapy in chronic beryllium disease". Eur. Respir. J. 32 (3): 687–93. doi:10.1183/09031936.00149607. PMID 18757698.
- ↑ Sood A, Beckett WS, Cullen MR (2004). "Variable response to long-term corticosteroid therapy in chronic beryllium disease". Chest. 126 (6): 2000–7. doi:10.1378/chest.126.6.2000. PMID 15596705.