Adult treatment panel guidelines (ATP III) for hypercholestrolemia

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Overview
Classification Familial hyperchylomicronemia Familial hypercholesterolemia Familial combined hyperlipidemia Dysbetalipoproteinemia Primary hypertriglyceridemia Mixed hyperlipoproteinemia
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]

Overview

The Adult Treatment Panel (ATP III) has adopted a classification for serum triglyceride level that helps in making treatment decisions. Elevated triglycerides are an independent risk factor for coronary heart diseases. It is commonly observed in persons with the metabolic syndrome, obesity, physical inactivity, smoking, excess alcohol intake, high-carbohydrate diets , diabetes type 2, chronic renal failure, nephrotic syndrome, certain drugs like corticosteroids, estrogens, retinoids and genetic disorders (familial combined hyperlipidemia, familial hypertriglyceridemia, and familial dysbetalipoproteinemia).

LDL Cholesterol and Non-HDL Cholesterol Goals

Risk category	LDL goal, mg/dL	Non-HDL goal, mg/dL
CHD and CHD risk equivalent (10 year risk for CHD is >20%)	< 100	< 130
Multiple (2+) risk factor (10 year risk for CHD is <20%)	< 130	< 160
0-1 risk factors	< 160	< 190

ATP III LDL cholesterol and Non-HDL cholesterol goals

Serum Triglyceride Classification

Classification	TG level, mg/dL
Normal TG level	< 150
Borderline-high TG level	150-199
High TG level	200-499
Very high TG level	>500

ATP III classification for triglyceride levels

References

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