Takayasu's arteritis history and symptoms: Difference between revisions
| Line 2: | Line 2: | ||
{{Takayasu's arteritis}} | {{Takayasu's arteritis}} | ||
{{CMG}} {{AE}} {{FKH}} | {{CMG}} {{AE}} {{FKH}} | ||
| Line 9: | Line 8: | ||
==History== | ==History== | ||
The disease can be divided into two phases: a pre-pulseless phase and subsequent pulseless phase. In the initial phase is pre-pulseless phase, patients present with non-specific constitutional symptoms of vasculitis, which may include any of the following: | The disease can be divided into two phases: a pre-pulseless phase and subsequent pulseless phase. In the initial phase is pre-pulseless phase, patients present with non-specific constitutional symptoms of vasculitis, which may include any of the following:<ref name="pmid7909656">{{cite journal |vauthors=Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M, Hoffman GS |title=Takayasu arteritis |journal=Ann. Intern. Med. |volume=120 |issue=11 |pages=919–29 |date=June 1994 |pmid=7909656 |doi= |url=}}</ref> | ||
Fatigue | Fatigue | ||
Fever of unknown origin | Fever of unknown origin | ||
Weight loss | Weight loss | ||
Myalgia | Myalgia | ||
Arthralgia | Arthralgia | ||
With progression of the disease and involvement of the branches of aorta, | |||
specific symptoms secondary to narrowing/occlusion of the branches of aorta become evident. | |||
* [[Subclavian artery]]: claudication in the upper extremities, subclavian steal syndrome | |||
* Carotid and vertebral arteries: headache, vertigo, syncope, convulsions and dementia | |||
* Coronary arteries: chest pain, angina which may progress to myocardial infarction | |||
* Ascending aorta: aortic regurgiatation | |||
Involvement of the [[subclavian artery]] is common and may lead to subclavian steal syndrome.<ref name="pmid15335">{{cite journal |vauthors=Yoneda S, Nukada T, Tada K, Imaizumi M, Takano T |title=Subclavian steal in Takayasu's arteritis. A hemodynamic study by means of ultrasonic Doppler flowmetry |journal=Stroke |volume=8 |issue=2 |pages=264–8 |date=1977 |pmid=15335 |doi= |url=}}</ref> In this syndrome, the stenosis of the subclavian artery, proximal to the origin of vertebral artery leads to the retrograde flow of blood from the vertebral artery back to subclavian artery during exercise, secondary to vasodilation of blood vessels. The retrograde flow of blood from the vertebral artery back towards subclavian compromises blood flow in the posterior cerebral bed, leading to various neurological symptoms including presyncope/syncope. | |||
Additional findings include skin lesions resembling erythema nodosum, erythema multiforme, pyoderma gangrenosum. In advanced stages of the disease, the occlusion of the vessels in the extremities may lead to ischemic ulcerations. | |||
===Common Symptoms=== | ===Common Symptoms=== | ||
Revision as of 19:47, 31 March 2018
|
Takayasu's arteritis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Takayasu's arteritis history and symptoms On the Web |
|
American Roentgen Ray Society Images of Takayasu's arteritis history and symptoms |
|
Risk calculators and risk factors for Takayasu's arteritis history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farnaz Khalighinejad, MD [2]
Overview
History
The disease can be divided into two phases: a pre-pulseless phase and subsequent pulseless phase. In the initial phase is pre-pulseless phase, patients present with non-specific constitutional symptoms of vasculitis, which may include any of the following:[1]
Fatigue
Fever of unknown origin
Weight loss
Myalgia
Arthralgia
With progression of the disease and involvement of the branches of aorta,
specific symptoms secondary to narrowing/occlusion of the branches of aorta become evident.
- Subclavian artery: claudication in the upper extremities, subclavian steal syndrome
- Carotid and vertebral arteries: headache, vertigo, syncope, convulsions and dementia
- Coronary arteries: chest pain, angina which may progress to myocardial infarction
- Ascending aorta: aortic regurgiatation
Involvement of the subclavian artery is common and may lead to subclavian steal syndrome.[2] In this syndrome, the stenosis of the subclavian artery, proximal to the origin of vertebral artery leads to the retrograde flow of blood from the vertebral artery back to subclavian artery during exercise, secondary to vasodilation of blood vessels. The retrograde flow of blood from the vertebral artery back towards subclavian compromises blood flow in the posterior cerebral bed, leading to various neurological symptoms including presyncope/syncope.
Additional findings include skin lesions resembling erythema nodosum, erythema multiforme, pyoderma gangrenosum. In advanced stages of the disease, the occlusion of the vessels in the extremities may lead to ischemic ulcerations.
Common Symptoms
Common symptoms of [disease] include:
Less Common Symptoms
References
- ↑ Kerr GS, Hallahan CW, Giordano J, Leavitt RY, Fauci AS, Rottem M, Hoffman GS (June 1994). "Takayasu arteritis". Ann. Intern. Med. 120 (11): 919–29. PMID 7909656.
- ↑ Yoneda S, Nukada T, Tada K, Imaizumi M, Takano T (1977). "Subclavian steal in Takayasu's arteritis. A hemodynamic study by means of ultrasonic Doppler flowmetry". Stroke. 8 (2): 264–8. PMID 15335.