Autoimmune hemolytic anemia differential diagnosis: Difference between revisions
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* Can be autosomal dominant or recessive | * Can be autosomal dominant or recessive | ||
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|[[Pernicious anemia]] | |[[Pernicious anemia]]<ref name="pmid27602354">{{cite journal| author=Chan CQ, Low LL, Lee KH| title=Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia. | journal=Front Med (Lausanne) | year= 2016 | volume= 3 | issue= | pages= 38 | pmid=27602354 | doi=10.3389/fmed.2016.00038 | pmc=4993789 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27602354 }} </ref> | ||
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* Autoimmune gastritis | * Autoimmune gastritis<ref name="pmid27602354">{{cite journal| author=Chan CQ, Low LL, Lee KH| title=Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia. | journal=Front Med (Lausanne) | year= 2016 | volume= 3 | issue= | pages= 38 | pmid=27602354 | doi=10.3389/fmed.2016.00038 | pmc=4993789 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27602354 }} </ref> | ||
* Production of anti-intrinsic factor antibodies | * Production of anti-intrinsic factor antibodies<ref name="pmid27602354">{{cite journal| author=Chan CQ, Low LL, Lee KH| title=Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia. | journal=Front Med (Lausanne) | year= 2016 | volume= 3 | issue= | pages= 38 | pmid=27602354 | doi=10.3389/fmed.2016.00038 | pmc=4993789 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27602354 }} </ref> | ||
* Production of anti-parietal cell antibodies | * Production of anti-parietal cell antibodies<ref name="pmid27602354">{{cite journal| author=Chan CQ, Low LL, Lee KH| title=Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia. | journal=Front Med (Lausanne) | year= 2016 | volume= 3 | issue= | pages= 38 | pmid=27602354 | doi=10.3389/fmed.2016.00038 | pmc=4993789 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27602354 }} </ref> | ||
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* Impaired vitamin B12 absorption due to absence of intrinsic factor | * Impaired vitamin B12 absorption due to absence of intrinsic factor | ||
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* Presence of anti-parietal cell antibodies | * Presence of anti-parietal cell antibodies | ||
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* | * Gastrointestinal discomfort | ||
* [[Weakness]] | * [[Weakness]] | ||
* [[Tingling]] | * [[Tingling]] | ||
* [[Paresthesias]] | * [[Paresthesias]] | ||
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* Lifelong [[vitamin B12]] therapy (1000mcg daily) | * Lifelong [[vitamin B12]] therapy (1000mcg daily)<ref name="pmid27602354">{{cite journal| author=Chan CQ, Low LL, Lee KH| title=Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia. | journal=Front Med (Lausanne) | year= 2016 | volume= 3 | issue= | pages= 38 | pmid=27602354 | doi=10.3389/fmed.2016.00038 | pmc=4993789 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27602354 }} </ref> | ||
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* Associated with diabetes, thyroid disease, vitiligo and other autoimmune conditions | * Associated with diabetes, thyroid disease, vitiligo and other autoimmune conditions | ||
Revision as of 01:25, 2 April 2018
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Autoimmune hemolytic anemia Microchapters |
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Differentiating Autoimmune hemolytic anemia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Autoimmune hemolytic anemia differential diagnosis On the Web |
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American Roentgen Ray Society Images of Autoimmune hemolytic anemia differential diagnosis |
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Autoimmune hemolytic anemia differential diagnosis in the news |
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Directions to Hospitals Treating Autoimmune hemolytic anemia |
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Risk calculators and risk factors for Autoimmune hemolytic anemia differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Assosciate Editor(s)-In-Chief: Prashanth Saddala M.B.B.S; Shyam Patel [2]
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Overview
Differentiating Autoimmune hemolytic anemia from other Diseases
Diagnosis is made by first ruling out other causes of hemolytic anemia, such as G6PD, thalassemia, sickle-cell disease, etc.
| Characteristic | Causes | Pathophysiology | Laboratory abnormalities | Physical examination | Therapy | Other associations |
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| Autoimmune hemolytic anemia |
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| Paroxysmal cold hemoglobinuria |
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| Hereditary spherocytosis[3] |
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| Pernicious anemia[4] |
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| Chronic lymphocytic leukemia |
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References
- ↑ 1.0 1.1 1.2 Berentsen S, Sundic T (2015). "Red blood cell destruction in autoimmune hemolytic anemia: role of complement and potential new targets for therapy". Biomed Res Int. 2015: 363278. doi:10.1155/2015/363278. PMC 4326213. PMID 25705656.
- ↑ 2.0 2.1 2.2 2.3 Akpoguma AO, Carlisle TL, Lentz SR (2015). "Case report: paroxysmal cold hemoglobinuria presenting during pregnancy". BMC Hematol. 15: 3. doi:10.1186/s12878-015-0023-7. PMC 4334594. PMID 25699184.
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Gallagher PG (2013). "Abnormalities of the erythrocyte membrane". Pediatr Clin North Am. 60 (6): 1349–62. doi:10.1016/j.pcl.2013.09.001. PMC 4155395. PMID 24237975.
- ↑ 4.0 4.1 4.2 4.3 4.4 Chan CQ, Low LL, Lee KH (2016). "Oral Vitamin B12 Replacement for the Treatment of Pernicious Anemia". Front Med (Lausanne). 3: 38. doi:10.3389/fmed.2016.00038. PMC 4993789. PMID 27602354.