Sjögren's syndrome medical therapy: Difference between revisions
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**Preferred regimen (1): Pilocarpine 5 mg PO q8h | **Preferred regimen (1): Pilocarpine 5 mg PO q8h | ||
**Preferred regimen (2): Cevimeline 30 mg PO q8h | **Preferred regimen (2): Cevimeline 30 mg PO q8h | ||
**Preferred regimen ( | **Preferred regimen (3): artificial tears | ||
*Pharmacologic medical therapies for organ-based disease and constitutional symptoms of Sjögren's syndrome include: | *Pharmacologic medical therapies for organ-based disease and constitutional symptoms of Sjögren's syndrome include: | ||
**Preferred regimen (1): Hydroxychloroquine 200 mg PO q24h | **Preferred regimen (1): Hydroxychloroquine 200 mg PO q24h | ||
**Preferred regimen (2): Methotrexate 0.2 mg/kg weekly | **Preferred regimen (2): Methotrexate 0.2 mg/kg weekly | ||
**Preferred regimen ( | **Preferred regimen (3): Leflunomide 20 mg/day | ||
**Preferred regimen ( | **Preferred regimen (4): Azathioprine 3 to 5 mg/kg once daily | ||
**Preferred regimen ( | **Preferred regimen (5): Sulfasalazine 30 mg PO q8h | ||
**Preferred regimen ( | **Preferred regimen (6): Cyclosporine 5 mg/kg/day | ||
**Preferred regimen ( | **Preferred regimen (7): Cyclophosphamide 50-100 mg/m²/day | ||
**Preferred regimen ( | **Preferred regimen (8): Rituximab 375 mg/m2 once weekly for 4 doses | ||
==References== | ==References== | ||
Revision as of 19:00, 4 April 2018
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Sjögren's syndrome Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Sjögren's syndrome medical therapy On the Web |
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American Roentgen Ray Society Images of Sjögren's syndrome medical therapy |
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Risk calculators and risk factors for Sjögren's syndrome medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farima Kahe M.D. [2]
Overview
Medical Therapy
- Pharmacologic medical therapies for dry eye, dry mouth, and other sicca symptom of Sjögren's syndrome include:
- Preferred regimen (1): Pilocarpine 5 mg PO q8h
- Preferred regimen (2): Cevimeline 30 mg PO q8h
- Preferred regimen (3): artificial tears
- Pharmacologic medical therapies for organ-based disease and constitutional symptoms of Sjögren's syndrome include:
- Preferred regimen (1): Hydroxychloroquine 200 mg PO q24h
- Preferred regimen (2): Methotrexate 0.2 mg/kg weekly
- Preferred regimen (3): Leflunomide 20 mg/day
- Preferred regimen (4): Azathioprine 3 to 5 mg/kg once daily
- Preferred regimen (5): Sulfasalazine 30 mg PO q8h
- Preferred regimen (6): Cyclosporine 5 mg/kg/day
- Preferred regimen (7): Cyclophosphamide 50-100 mg/m²/day
- Preferred regimen (8): Rituximab 375 mg/m2 once weekly for 4 doses