PVC induced cardiomyopathy: Difference between revisions
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== Treatment == | == Treatment == | ||
* Anti-arrhythmic drugs: | |||
* ablation: | |||
==References == | ==References == | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 14:49, 6 April 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Historical perspective
In 1998, a study demonstrated that treating patients with frequent PVCs ( > 20,000 per day ) and ventricular dysfunction with amiodarone could significantly improve LVEF.[1] This result led to the initial assumption that frequent PVCs might cause a reversible form of cardiomyopathy and thus, the concept of PVC-induced cardiomyopathy as a separate entity was formed. Since then, multiple studies have attempted to clarify the nature and the features of the disease. However, the mechanisms through which frequent PVCs can cause ventricular dysfunction remain mainly unknown. Initial studies suggested that PVC-induced cardiomyopathy was essentially a tachycardia-induced cardiomyopathy as seen with other arrhythmias such as atrial fibrillation.[2] This hypothesis was rejected, however, because many patients with PVC-induced cardiomyopathy had normal average heart rates.[3]
Pathophysiology
Causes and risk factors
Natural history, complications, and prognosis
History and symptoms
Physical exam
Electrocardiogram
Echocardiography
Treatment
- Anti-arrhythmic drugs:
- ablation:
References
- ↑ Duffee DF, Shen WK, Smith HC (1998). "Suppression of frequent premature ventricular contractions and improvement of left ventricular function in patients with presumed idiopathic dilated cardiomyopathy". Mayo Clin Proc. 73 (5): 430–3. doi:10.1016/S0025-6196(11)63724-5. PMID 9581582.
- ↑ Ellis ER, Josephson ME (2013). "Heart failure and tachycardia-induced cardiomyopathy". Curr Heart Fail Rep. 10 (4): 296–306. doi:10.1007/s11897-013-0150-z. PMID 23963583.
- ↑ Zhong L, Lee YH, Huang XM, Asirvatham SJ, Shen WK, Friedman PA; et al. (2014). "Relative efficacy of catheter ablation vs antiarrhythmic drugs in treating premature ventricular contractions: a single-center retrospective study". Heart Rhythm. 11 (2): 187–93. doi:10.1016/j.hrthm.2013.10.033. PMID 24157533.