Reactive arthritis natural history, complications and prognosis: Difference between revisions
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==Complications== | ==Complications== | ||
==Prognosis== | ==Prognosis== | ||
*Prognosis is generally good for patients with reactive arthritis. | *Prognosis is generally good for patients with reactive arthritis.<ref name="pmid20216128">{{cite journal |vauthors=Wechalekar MD, Rischmueller M, Whittle S, Burnet S, Hill CL |title=Prolonged remission of chronic reactive arthritis treated with three infusions of infliximab |journal=J Clin Rheumatol |volume=16 |issue=2 |pages=79–80 |date=March 2010 |pmid=20216128 |doi=10.1097/RHU.0b013e3181d06f70 |url=}}</ref><ref name="pmid7837155">{{cite journal |vauthors=Amor B, Santos RS, Nahal R, Listrat V, Dougados M |title=Predictive factors for the longterm outcome of spondyloarthropathies |journal=J. Rheumatol. |volume=21 |issue=10 |pages=1883–7 |date=October 1994 |pmid=7837155 |doi= |url=}}</ref> | ||
*Patients who receive treatment have rapid reversal of symptoms. | *Patients who receive and respond to treatment generally have rapid reversal of symptoms. | ||
* | *It is estimated that around 25% of patients develop long term complication of arthropathy. | ||
*Long term complications are mostly seen in patients who are unresponsive to NSAIDs and have elevated ESR. | |||
*Patients who are HLA-B27 positive have a high rate of recurrence (upto 50%). | |||
==References== | ==References== | ||
Revision as of 18:33, 6 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History
- The symptoms of reactive arthritis usually develop after 1-3 weeks of initial infection (in another part of the body) and start with symptoms such as malaise, fatigue, and fever.
- Majority of the patients have a self limited course with complete healing within 3-12 months.
- If left untreated, patients with reactive arthritis may progress to develop myalgias and joint pain especially in the lower extremities. Over the course of time, patient develops urethritis and conjunctivitis.
- Urethritis presents with dysuria, increased frequency, urgency, and urethral discharge whereas conjunctivitis leads to pain, burning, and tearing sensation in eyes.
Complications
Prognosis
- Prognosis is generally good for patients with reactive arthritis.[1][2]
- Patients who receive and respond to treatment generally have rapid reversal of symptoms.
- It is estimated that around 25% of patients develop long term complication of arthropathy.
- Long term complications are mostly seen in patients who are unresponsive to NSAIDs and have elevated ESR.
- Patients who are HLA-B27 positive have a high rate of recurrence (upto 50%).
References
- ↑ Wechalekar MD, Rischmueller M, Whittle S, Burnet S, Hill CL (March 2010). "Prolonged remission of chronic reactive arthritis treated with three infusions of infliximab". J Clin Rheumatol. 16 (2): 79–80. doi:10.1097/RHU.0b013e3181d06f70. PMID 20216128.
- ↑ Amor B, Santos RS, Nahal R, Listrat V, Dougados M (October 1994). "Predictive factors for the longterm outcome of spondyloarthropathies". J. Rheumatol. 21 (10): 1883–7. PMID 7837155.