Takayasu's arteritis causes: Difference between revisions
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** Immunohistopathologic examination has shown that the infiltrating cells in aortic tissue mainly consist of killer cells, especially gamma delta [[T lymphocytes]]. | ** Immunohistopathologic examination has shown that the infiltrating cells in aortic tissue mainly consist of killer cells, especially gamma delta [[T lymphocytes]]. | ||
* Infectious agents: | * Infectious agents: | ||
** | ** Spirochetes | ||
** | ** ''Mycobacterium tuberculosis'' | ||
** | ** Streptococcal organisms | ||
==References== | ==References== | ||
Revision as of 19:38, 6 April 2018
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Takayasu's arteritis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Takayasu's arteritis causes On the Web |
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American Roentgen Ray Society Images of Takayasu's arteritis causes |
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Risk calculators and risk factors for Takayasu's arteritis causes |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Farnaz Khalighinejad, MD [2]
Overview
Causes
The cause of Takayasu's arteritis is idiopathic but genetic, immunologic and infectious factors play important role in the development of Takayasu's arteritis.
- Genetic factors:
- Takayasu arteritis has been associated with different human leucocyte antigen (HLA) alleles in different populations.
- In Japan and Korea there is a clear association with the extended haplotype: HLA B*52, DRB1*1502, DRB5*0102, DQA1*0103, DQB1*0601, DPA1*02-DPB1*0901.[1]
- Immunologic:
- Immunohistopathologic examination has shown that the infiltrating cells in aortic tissue mainly consist of killer cells, especially gamma delta T lymphocytes.
- Infectious agents:
- Spirochetes
- Mycobacterium tuberculosis
- Streptococcal organisms