Seronegative spondyloarthritis: Difference between revisions
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==Classification Criteria== | ==Classification Criteria== | ||
===ASAS classification criteria for axial spondyloarthritis (axial SpA)=== | ===ASAS classification criteria for axial spondyloarthritis (axial SpA)=== | ||
The Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (axial SpA) include: | The Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (axial SpA) include:<ref name="pmid19297344">{{cite journal| author=Rudwaleit M, van der Heijde D, Landewé R, Listing J, Akkoc N, Brandt J et al.| title=The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection. | journal=Ann Rheum Dis | year= 2009 | volume= 68 | issue= 6 | pages= 777-83 | pmid=19297344 | doi=10.1136/ard.2009.108233 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19297344 }} </ref> | ||
*Patient with back pain ≥ 3 months and age of onset <45 years should fulfill either of the two criteria: | *Patient with back pain ≥ 3 months and age of onset <45 years should fulfill either of the two criteria: | ||
*# Sacroiliitis on imaging<sup>'''*'''</sup> plus ≥ 1 feature of SpA<sup>'''**'''</sup> | *# Sacroiliitis on imaging<sup>'''*'''</sup> plus ≥ 1 feature of SpA<sup>'''**'''</sup> | ||
Revision as of 16:23, 9 April 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
"Seronegative" refers to the fact that these diseases are negative for Rheumatoid factor and CCP in the serum.
Classsiication
Algorithm showing classification of seronegative spondyloarthritis[1]
| Seronegative Spondyloarthritis (SpA) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Axial SpA including Ankylosing spondylitis | Peripheral SpA | Psoriatic arthritis | Reactive arthritis | Inflammatory bowel disease related arthritis | Juvenile spondyloarthritis | ||||||||||||||||||||||||||||||||||||||||||||||||||||
Classification Criteria
ASAS classification criteria for axial spondyloarthritis (axial SpA)
The Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (axial SpA) include:[2]
- Patient with back pain ≥ 3 months and age of onset <45 years should fulfill either of the two criteria:
- Sacroiliitis on imaging* plus ≥ 1 feature of SpA**
- HLA-B27 plus ≥ 2 feature of SpA**
- *Sacroiliitis on imaging:
- Active (acute) inflammation on MRI highly suggestive of sacroiliitis associated with SpA
- OR
- Definite radiographic sacroillitis accorging to modified New York criteria
- **SpA features:
- Inflammatroy back pain
- Arthritis
- Enthesotos (heel)
- Uveitis
- Dactylitis
- Psoriasis
- Crohn's disease or ulcerative colitis
- Good response to NSAIDs
- Family history for SpA
- HLA-B27
- Elevated CRP
- *Sacroiliitis on imaging:
ASAS classification criteria for peripheral spondyloarthritis
Differential
Diagnosis
These diseases has following conditions in common:
- They are in relation to HLA-B27
- sacroiliitis and spondylitis are present in them.
- familial aggregation occurs
- Overlap is likely in them
- rheumatoid factor is not present
References
- ↑ Dougados M, Baeten D (2011). "Spondyloarthritis". Lancet. 377 (9783): 2127–37. doi:10.1016/S0140-6736(11)60071-8. PMID 21684383.
- ↑ Rudwaleit M, van der Heijde D, Landewé R, Listing J, Akkoc N, Brandt J; et al. (2009). "The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection". Ann Rheum Dis. 68 (6): 777–83. doi:10.1136/ard.2009.108233. PMID 19297344.