Churg-Strauss syndrome laboratory findings: Difference between revisions

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__NOTOC__
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{{Churg-Strauss syndrome}}
{{Churg-Strauss syndrome}}
{{CMG}}{{APM}}{{AE}}{{KW}}
 
{{CMG}}; {{AE}}{{CK}}


==Overview==
==Overview==
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE).
An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
 
OR
 
Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
 
OR
 
[Test] is usually normal for patients with [disease name].
 
OR
 
Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].
 
OR
 
There are no diagnostic laboratory findings associated with [disease name].


==Laboratory Findings==
==Laboratory Findings==
Laboratory findings consistent with the diagnosis of Eosinophilic granulomatosis with polyangiitis include, antineutrophil cytoplasmic antibodies, hypereosinophilia, and elevated immunoglobulin E titers (IgE). Routine laboratory tests that are used to identify Eosinophilic granulomatosis with polyangiitis are:<ref name="pmid14819261">{{cite journal| author=CHURG J, STRAUSS L| title=Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. | journal=Am J Pathol | year= 1951 | volume= 27 | issue= 2 | pages= 277-301 | pmid=14819261 | doi= | pmc=1937314 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14819261  }}</ref> <ref name="pmid24530234">{{cite journal| author=Mouthon L, Dunogue B, Guillevin L| title=Diagnosis and classification of eosinophilic granulomatosis with polyangiitis (formerly named Churg-Strauss syndrome). | journal=J Autoimmun | year= 2014 | volume= 48-49 | issue=  | pages= 99-103 | pmid=24530234 | doi=10.1016/j.jaut.2014.01.018 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24530234  }}</ref>


'''Blood Work-up''' 
*There are no diagnostic laboratory findings associated with [disease name].
* Complete blood count (CBC)
OR
* Uremia
*An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
* Serum creatinine
*[Test] is usually normal among patients with [disease name].
* Blood urea nitrogen (BUN)
*Laboratory findings consistent with the diagnosis of [disease name] include:
* Antineutrophil cytoplasmic antibody test
**[Abnormal test 1]
* Eosinophilia
**[Abnormal test 2]
* Immunoglobulin 
**[Abnormal test 3]
* Erythrocyte sedimentation rate (ESR)
* C-reactive protein (CRP)
* Serum troponin<ref name="pmid23853013">{{cite journal| author=McAleavey N, Millar A, Pendleton A| title=Cardiac involvement as the main presenting feature in eosinophilic granulomatosis with polyangiitis. | journal=BMJ Case Rep | year= 2013 | volume= 2013 | issue=  | pages=  | pmid=23853013 | doi=10.1136/bcr-2013-009394 | pmc=3736255 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23853013  }}</ref>
* Rheumatoid factor 
'''Urinalysis'''
* Proteinuria
* Microscopic hematuria
* Albuminuria
* Red blood cell casts
'''Biopsy'''
 
The gold standard in establishing a diagnosis for Eosinophilic granulomatosis with polyangiitis is a lung biopsy.<ref name="pmid7952571">{{cite journal| author=Allen JN, Davis WB| title=Eosinophilic lung diseases. | journal=Am J Respir Crit Care Med | year= 1994 | volume= 150 | issue= 5 Pt 1 | pages= 1423-38 | pmid=7952571 | doi=10.1164/ajrccm.150.5.7952571 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7952571  }} </ref>   


*Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
[[Category:Disease]]
[[Category:Pulmonology]]
[[Category:Autoimmune diseases]]
[[Category:Rheumatology]]


{{WH}}
{{WH}}
{{WS}}
{{WS}}
[[Category: (name of the system)]]

Revision as of 23:07, 9 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chandrakala Yannam, MD [2]

Overview

An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].

OR

Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

OR

[Test] is usually normal for patients with [disease name].

OR

Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

OR

There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

  • There are no diagnostic laboratory findings associated with [disease name].

OR

  • An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
  • [Test] is usually normal among patients with [disease name].
  • Laboratory findings consistent with the diagnosis of [disease name] include:
    • [Abnormal test 1]
    • [Abnormal test 2]
    • [Abnormal test 3]
  • Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

References

Template:WH Template:WS

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