Glomerulonephritis differential diagnosis: Difference between revisions
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==Differential Diagnosis== | ==Differential Diagnosis== | ||
Glomerulonephritis | {| class="wikitable" | ||
!Glomerulonephritis | |||
!Sub-entity | |||
!Causes and associations | |||
!History and symtoms | |||
!Nephrotic features | |||
!Nephritic features | |||
!ANCA | |||
!Anti-glomerular basement membrane antibody (Anti-GBM antibody) | |||
!Immune complex formation | |||
!Light microscope | |||
!Electron microscope | |||
!Immunoflourescence pattern | |||
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! rowspan="3" |Non-proliferative | |||
!Minimal change disease | |||
! | |||
* Idiopathic | |||
* Protein tyrosine phosphatase receptor type O (glomerular epithelial protein 1- GLEPP1) | |||
! | |||
* Young children | |||
* Recent infection and immunization | |||
* Atopy | |||
* Hodgkin lymphoma | |||
* Thrombosis (due to urinary loss of antithrombin-III) | |||
* Pitting edema | |||
* Hyperlipidemia and hyper colesterolemia | |||
!+ | |||
!- | |||
!- | |||
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!Normal | |||
!Fusion of podocytes | |||
!- | |||
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!Focal segmental glomerulosclerosis | |||
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* Idiopathic | |||
* HIV | |||
* Heroine use | |||
* Sickle cell disease | |||
* Interferon | |||
* Severe obesity | |||
* Mixed cryoglobunemia (Hepatitis C) | |||
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* Adults | |||
* Pitting edema | |||
* Hyperlipidemia and hyper colesterolemia | |||
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!Membranous glomerulonephritis | |||
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* Idiopathic | |||
* Hepatitis B and C | |||
* Solid tumors | |||
* Systemic lupus erythmatosus | |||
* Drugs (NSAIDS, penclliamine, gold, captopril) | |||
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| rowspan="7" |Proliferative | |||
|IgA nephropathy | |||
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* Idiopathic | |||
* Viral infections | |||
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* Young children | |||
* History of mucosal infections (e.g. gastroenteritis) and upper respiratory tract infection | |||
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| + | |||
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| rowspan="5" |Rapidly progressive glomerulonephritis | |||
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* Goodpasture syndrome | |||
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* Post infectious glomerulonephritis | |||
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* Granulomatosis with polyangitis (Wegner's granulomatosis) | |||
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* Churg Strauss syndrome | |||
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* Microscopic polyngitis | |||
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|Membranoproliferative glomerulonephritis | |||
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* Idiopathic | |||
* Hepatitis B and C (Type 1) | |||
* C3 nepritic factor (Type2) | |||
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==References== | ==References== |
Revision as of 05:00, 11 April 2018
Glomerulonephritis Main page |
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Overview
Differential Diagnosis
Glomerulonephritis | Sub-entity | Causes and associations | History and symtoms | Nephrotic features | Nephritic features | ANCA | Anti-glomerular basement membrane antibody (Anti-GBM antibody) | Immune complex formation | Light microscope | Electron microscope | Immunoflourescence pattern |
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Non-proliferative | Minimal change disease |
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+ | - | - | Normal | Fusion of podocytes | - | ||
Focal segmental glomerulosclerosis |
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Membranous glomerulonephritis |
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Proliferative | IgA nephropathy |
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Rapidly progressive glomerulonephritis |
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Membranoproliferative glomerulonephritis |
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