Churg-Strauss syndrome (patient information): Difference between revisions
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==Overview== | ==Overview== | ||
[[Eosinophilic granulomatosis with polyangiitis]] previously called [[Eosinophilic granulomatosis with polyangiitis|Churg-Strauss syndrome]] is a small and medium-sized necrotizing [[vasculitis]], with extravascular [[granuloma]] formation. The disease was first described by Churg and Strauss in 1951. The [[etiology]] is not known. However, various environmental factors, [[Allergen|allergens]], [[genetics]], and [[:Category:Drugs|drugs]] may play a role in triggering [[disease]] process by activating [[Eosinophil granulocyte|eosinophils]], [[B cell|B]] and [[T cell|T lymphocytes]] and [[Macrophage|macrophages]]. The disease is characterized by the presence of [[asthma]], peripheral [[eosinophilia]], [[rhinosinusitis]], [[peripheral neuropathy]] and multiple [[Organ (anatomy)|organ]] involvements including [[skin]], [[Gastrointestinal tract|GI tract]], and [[kidney]]. | |||
==What are the symptoms of Churg-Strauss syndrome?== | ==What are the symptoms of Churg-Strauss syndrome?== | ||
Revision as of 18:12, 12 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Eosinophilic granulomatosis with polyangiitis previously called Churg-Strauss syndrome is a small and medium-sized necrotizing vasculitis, with extravascular granuloma formation. The disease was first described by Churg and Strauss in 1951. The etiology is not known. However, various environmental factors, allergens, genetics, and drugs may play a role in triggering disease process by activating eosinophils, B and T lymphocytes and macrophages. The disease is characterized by the presence of asthma, peripheral eosinophilia, rhinosinusitis, peripheral neuropathy and multiple organ involvements including skin, GI tract, and kidney.