Churg-Strauss syndrome (patient information): Difference between revisions
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==Overview== | ==Overview== | ||
[[Eosinophilic granulomatosis with polyangiitis]] previously called [[Eosinophilic granulomatosis with polyangiitis|Churg-Strauss syndrome]] | [[Eosinophilic granulomatosis with polyangiitis]] previously called [[Eosinophilic granulomatosis with polyangiitis|Churg-Strauss syndrome]] involves primarily small and medium sized blood vessels resulting in vessel inflammation. The exact cause of the disease is not known. However, various environmental factors, [[Allergen|allergens]], [[genetics]], and [[:Category:Drugs|drugs]] may play a role in triggering [[disease]] process by activating different types of white blood cells. The disease is characterized by the presence of [[asthma]], peripheral [[eosinophilia]], [[rhinosinusitis]], [[Paresthesia|tingling and numbness of hands and feet]] ([[peripheral neuropathy]]) and multiple [[Organ (anatomy)|organ]] involvements including [[skin]], [[Gastrointestinal tract|GI tract]], and [[kidney]]. | ||
==What are the symptoms of Churg-Strauss syndrome== | ==What are the symptoms of Churg-Strauss syndrome== | ||
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[[Symptom|Symptoms]] of [[eosinophilic granulomatosis with polyangiitis]] typically develops through three phases, include prodromal phase, eosinophilic phase, and vasculitis phase. Although these phases cannot be clinically distinguishable. | [[Symptom|Symptoms]] of [[eosinophilic granulomatosis with polyangiitis]] typically develops through three phases, include prodromal phase, eosinophilic phase, and vasculitis phase. Although these phases cannot be clinically distinguishable. | ||
* '''Prodromal phase:''' Most common manifestations include | * '''Prodromal phase:''' Most common manifestations include | ||
** | **[[Rhinorrhea|Runny nose]] | ||
** Sneezing | ** [[Sneeze|Sneezing]] | ||
** Nasal polyps | ** [[Nasal polyp|Nasal polyps]] | ||
** [[ | ** [[Rhinosinusitis|Sinusitis]] | ||
** [[ | ** [[Asthma]] | ||
* '''Eosinophilic phase:''' This phase is characterized by [[Eosinophilia| | * '''Eosinophilic phase:''' This phase is characterized by [[Eosinophilia|eosinophilia]] and accumulation of [[Eosinophil granulocyte|eosinophils]] in various organs. Most commonly involved organs are [[lung]] and [[Gastrointestinal tract|GI tract]]. | ||
** Asthma | ** [[Asthma]] | ||
** Cough | ** [[Cough]] | ||
** Dyspnea | ** [[Dyspnea|Shortness of breath]] | ||
** Abdominal pain | ** [[Abdominal pain]] | ||
** GI bleeding | ** GI bleeding | ||
** Fatigue | ** [[Fatigue]] | ||
* '''Vasculitic phase:''' Symptoms depending on organ system involvement. Most commonly involved organs are lungs, kidneys, skin, heart, and peripheral nerves. | * '''Vasculitic phase:''' Symptoms depending on organ system involvement. Most commonly involved organs are lungs, kidneys, skin, heart, and peripheral nerves. | ||
** Weight loss | ** [[Weight loss]] | ||
** Generalized weakness | ** Generalized weakness | ||
** | ** [[Fatigue]] | ||
** Skin rash and nodules | ** [[Rash|Skin rash]] and nodules | ||
** Numbness and tingling sensation of hands and feet | ** [[Paresthesia|Numbness and tingling sensation of hands and feet]] | ||
** Abdominal pain | ** [[Abdominal pain]] | ||
** Diarrhea | ** [[Diarrhea]] | ||
** Nausea and vomiting | ** [[Nausea and vomiting]] | ||
** Shortness of breath | ** [[Dyspnea|Shortness of breath]] | ||
** [[Chest pain]] | |||
** Chest pain | ** [[Hematuria|Blood in urine]] | ||
** Blood in | |||
==What causes Churg-Strauss syndrome?== | ==What causes Churg-Strauss syndrome?== | ||
Revision as of 18:52, 12 April 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Eosinophilic granulomatosis with polyangiitis previously called Churg-Strauss syndrome involves primarily small and medium sized blood vessels resulting in vessel inflammation. The exact cause of the disease is not known. However, various environmental factors, allergens, genetics, and drugs may play a role in triggering disease process by activating different types of white blood cells. The disease is characterized by the presence of asthma, peripheral eosinophilia, rhinosinusitis, tingling and numbness of hands and feet (peripheral neuropathy) and multiple organ involvements including skin, GI tract, and kidney.
What are the symptoms of Churg-Strauss syndrome
Symptoms of eosinophilic granulomatosis with polyangiitis typically develops through three phases, include prodromal phase, eosinophilic phase, and vasculitis phase. Although these phases cannot be clinically distinguishable.
- Prodromal phase: Most common manifestations include
- Eosinophilic phase: This phase is characterized by eosinophilia and accumulation of eosinophils in various organs. Most commonly involved organs are lung and GI tract.
- Asthma
- Cough
- Shortness of breath
- Abdominal pain
- GI bleeding
- Fatigue
- Vasculitic phase: Symptoms depending on organ system involvement. Most commonly involved organs are lungs, kidneys, skin, heart, and peripheral nerves.
- Weight loss
- Generalized weakness
- Fatigue
- Skin rash and nodules
- Numbness and tingling sensation of hands and feet
- Abdominal pain
- Diarrhea
- Nausea and vomiting
- Shortness of breath
- Chest pain
- Blood in urine
What causes Churg-Strauss syndrome?
There are no established causes for eosinophilic granulomatosis with polyangiitis. However, various allergens, infections, vaccinations and drugs may act as a triggering agents, and are responsible for developing disease. Genetics may also play a role.