Polyarthritis: Difference between revisions

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==Causes==
==Causes==
Polyarthritis is most often caused by an [[Auto-immune|auto-immune disorder]] such as [[Rheumatoid arthritis]], [[Psoriatic arthritis]], and [[Lupus erythematosus]] but can also be caused by infections such as Ross River Virus.
Polyarthritis is most often caused by an [[Auto-immune|auto-immune disorder]] such as [[Rheumatoid arthritis]], [[Psoriatic arthritis]], and [[Lupus erythematosus]] but can also be caused by infections such as Ross River Virus.
== Differential Diagnosis of Polyarthritis ==
{| align="center" style="border: 0px; font-size: 90%; margin: 3px;"
! colspan="3" rowspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" |Diseases
| colspan="8" rowspan="1" align="center" style="background:#4479BA; color: #FFFFFF;" |'''Clinical manifestations'''
! colspan="9" rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Para-clinical findings
| colspan="1" rowspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" |'''Gold standard'''
! rowspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" |Additional findings
|-
| colspan="5" rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |'''Symptoms'''
! colspan="3" rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Physical examination
|-
! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" |Lab Findings
! colspan="4" align="center" style="background:#4479BA; color: #FFFFFF;" |Imaging
! rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;" |Histopathology
|-
! align="center" style="background:#4479BA; color: #FFFFFF;" |Joint Swelling
! colspan="1" rowspan="1" align="center" style="background:#4479BA; color: #FFFFFF;" |Fever
! align="center" style="background:#4479BA; color: #FFFFFF;" |Weight loss
! align="center" style="background:#4479BA; color: #FFFFFF;" |Numbness
! align="center" style="background:#4479BA; color: #FFFFFF;" |Claudication
! align="center" style="background:#4479BA; color: #FFFFFF;" |Paresthesia
! colspan="1" rowspan="1" align="center" style="background:#4479BA; color: #FFFFFF;" |Warm joint
! align="center" style="background:#4479BA; color: #FFFFFF;" |Morning stiffness
! align="center" style="background:#4479BA; color: #FFFFFF;" |Biomarker
! align="center" style="background:#4479BA; color: #FFFFFF;" |CBC
! align="center" style="background:#4479BA; color: #FFFFFF;" |ESR
! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
! align="center" style="background:#4479BA; color: #FFFFFF;" |X-ray
! align="center" style="background:#4479BA; color: #FFFFFF;" |CT scan
! align="center" style="background:#4479BA; color: #FFFFFF;" |Synovial fluid
! align="center" style="background:#4479BA; color: #FFFFFF;" |Other
|-
! rowspan="24" |Polyarthritis
! rowspan="2" |Infectious arthritis
!Lyme disease
!
!
!
!
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!Bacterial endocarditis
!
!
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!
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! rowspan="3" |'''Postinfectious (reactive) arthritis'''
!Rheumatic fever
!
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!Reactive arthritis
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!Enteric infection
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! rowspan="3" |'''Other seronegative spondyloarthritides'''
!Ankylosing spondylitis
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!Psoriatic arthritis
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!Inflammatory bowel disease
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! colspan="2" |'''Rheumatoid arthritis'''
!
!
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! colspan="2" |'''Inflammatory osteoarthritis'''
!
!
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! colspan="2" |'''Crystal-induced arthritis'''
!
!
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!
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!
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! rowspan="8" |'''Systemic rheumatic illnesses'''
!Systemic lupus erythematosus
!
!
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!Systemic vasculitis
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!
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!Systemic sclerosis
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!
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!Polymyositis/dermatomyositis
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!Still's disease
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!Behçet's syndrome
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!Relapsing polychondritis
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!Autoinflammatory disorders
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! rowspan="5" |'''Other systemic illnesses'''
!Sarcoidosis
!
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!Palindromic rheumatism
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!Familial Mediterranean fever
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!Malignancy
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!Hyperlipoproteinemias
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! rowspan="10" |Polyarticular pain
! rowspan="3" |Viral arthritis
|'''Hepatitis B and C'''
!
!
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|'''Rubella'''
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|'''Parvovirus'''
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! colspan="2" |Fibromyalgia
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! colspan="2" |Multiple sites of bursitis or tendinitis
!
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! colspan="2" |Soft tissue abnormalities
!
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! colspan="2" |Hypothyroidism
!
!
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! colspan="2" |Neuropathic pain
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!
!
!
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! colspan="2" |Metabolic bone disease
!
!
!
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!
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!
!
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|-
! colspan="2" |Depression
!
!
!
!
!
!
!
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!
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!
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!
!
!
!
!
!
|-
|}
==References==
==References==
{{reflist|2}}
{{reflist|2}}

Revision as of 17:12, 16 April 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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Overview

Polyarthritis is any type of arthritis which involves five or more joints - an inflammation of two, three or four joints is an oligoarthritis.

Causes

Polyarthritis is most often caused by an auto-immune disorder such as Rheumatoid arthritis, Psoriatic arthritis, and Lupus erythematosus but can also be caused by infections such as Ross River Virus.

Differential Diagnosis of Polyarthritis

Diseases Clinical manifestations Para-clinical findings Gold standard Additional findings
Symptoms Physical examination
Lab Findings Imaging Histopathology
Joint Swelling Fever Weight loss Numbness Claudication Paresthesia Warm joint Morning stiffness Biomarker CBC ESR Other X-ray CT scan Synovial fluid Other
Polyarthritis Infectious arthritis Lyme disease
Bacterial endocarditis
Postinfectious (reactive) arthritis Rheumatic fever
Reactive arthritis
Enteric infection
Other seronegative spondyloarthritides Ankylosing spondylitis
Psoriatic arthritis
Inflammatory bowel disease
Rheumatoid arthritis
Inflammatory osteoarthritis
Crystal-induced arthritis
Systemic rheumatic illnesses Systemic lupus erythematosus
Systemic vasculitis
Systemic sclerosis
Polymyositis/dermatomyositis
Still's disease
Behçet's syndrome
Relapsing polychondritis
Autoinflammatory disorders
Other systemic illnesses Sarcoidosis
Palindromic rheumatism
Familial Mediterranean fever
Malignancy
Hyperlipoproteinemias
Polyarticular pain Viral arthritis Hepatitis B and C
Rubella
Parvovirus
Fibromyalgia
Multiple sites of bursitis or tendinitis
Soft tissue abnormalities
Hypothyroidism
Neuropathic pain
Metabolic bone disease
Depression

References

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