Adult-onset Still's disease historical perspective: Difference between revisions
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* Adult-onset Still's disease is an inflammatory condition characterized by high spiking fevers, rash, sore throat, and joint pain.<ref name="urlAdult Still disease: MedlinePlus Medical Encyclopedia">{{cite web |url=https://medlineplus.gov/ency/article/000450.htm |title=Adult Still disease: MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref> | * Adult-onset Still's disease is an inflammatory condition characterized by high spiking fevers, rash, sore throat, and joint pain.<ref name="urlAdult Still disease: MedlinePlus Medical Encyclopedia">{{cite web |url=https://medlineplus.gov/ency/article/000450.htm |title=Adult Still disease: MedlinePlus Medical Encyclopedia |format= |work= |accessdate=}}</ref> | ||
* As it progresses, adult-onset Still's disease may lead to chronic arthritis and other complications. | * As it progresses, adult-onset Still's disease may lead to chronic arthritis and other complications. | ||
* In 1896, an English doctor named George Still, described the condition in children and the disease is named after him.<ref name="urlWhat is Still’s Disease? | Stills Disease Information Center">{{cite web |url=http://www.stillsdisease.org/index.php/stills-info/ |title=What is Still’s Disease? | Still's Disease Information Center |format= |work= |accessdate=}}</ref> | * In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him.<ref name="urlWhat is Still’s Disease? | Stills Disease Information Center">{{cite web |url=http://www.stillsdisease.org/index.php/stills-info/ |title=What is Still’s Disease? | Still's Disease Information Center |format= |work= |accessdate=}}</ref> | ||
* Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA). | * Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA). | ||
* In 1971, the term "adult Still's disease" was used | * In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA. | ||
* The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and infections (pathogen-associated molecular patterns- PAMPs) | * The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and infections (pathogen-associated molecular patterns- PAMPs) | ||
* There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission. | * There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission. | ||
Revision as of 22:02, 22 April 2018
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Adult-onset Still's disease |
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Differentiating Adult-onset Still’s Disease from other Diseases |
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Template:Adult-onset Still's disease On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Historical Perspective
- Adult-onset Still's disease is an inflammatory condition characterized by high spiking fevers, rash, sore throat, and joint pain.[1]
- As it progresses, adult-onset Still's disease may lead to chronic arthritis and other complications.
- In 1896, an English doctor named George Frederick Still, described the condition in children and the disease is named after him.[2]
- Still's disease occurring in children < 16 years is now referred to as systemic onset juvenile rheumatoid arthritis (JRA).
- In 1971, EG Bywaters described the term "adult Still's disease" which was later used for adults who had a condition similar to systemic onset JRA.
- The cause of adult-onset Still's disease is unknown. Risk factors known to be associated with Still's disease are stress and infections (pathogen-associated molecular patterns- PAMPs)
- There's no cure for adult-onset Still's disease; however, symptomatic treatment using corticosteroids, anti-interleukin agents and disease modifying anti-rheumatic drugs (DMARDs) may provide relief, and aid in remission.