Chronic myelogenous leukemia other diagnostic studies: Difference between revisions
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cytogenetic studies for Ph and markers of karyotypic evolution. In patients who are Ph negative, molecular studies, such as Southern blot assay or polymerase chain reaction (PCR), are indicated to detect the BCR-ABL rearrangements.PMID:10428738 | cytogenetic studies for Ph and markers of karyotypic evolution. In patients who are Ph negative, molecular studies, such as Southern blot assay or polymerase chain reaction (PCR), are indicated to detect the BCR-ABL rearrangements.PMID:10428738 | ||
Cytogenetic analysis is the gold standard diagnostic test in chronic myelogenous leukemia. | |||
PMID: | |||
: 10428738 | |||
==Other diagnostic studies== | ==Other diagnostic studies== | ||
Other diagnostic studies for chronic myelogenous leukemia include:<ref name="cancer.ca">Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/diagnosis/?region=ab</ref> | Other diagnostic studies for chronic myelogenous leukemia include:<ref name="cancer.ca">Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/diagnosis/?region=ab</ref> |
Revision as of 13:52, 13 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Other diagnostic studies for chronic myelogenous leukemia include bone marrow aspiration and biopsy, lumbar puncture, and lymph node biopsy.
cytogenetic studies for Ph and markers of karyotypic evolution. In patients who are Ph negative, molecular studies, such as Southern blot assay or polymerase chain reaction (PCR), are indicated to detect the BCR-ABL rearrangements.PMID:10428738
Cytogenetic analysis is the gold standard diagnostic test in chronic myelogenous leukemia.
PMID:
- 10428738
Other diagnostic studies
Other diagnostic studies for chronic myelogenous leukemia include:[1]
- Used to detect and/or determine the type of leukemic cells
- Used to detect any metastasis to the cerebral spinal fluid (CSF)
- Used to detect and/or determine the type of leukemic cells
Gallery
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Bone marrow aspiration and biopsy. After a small area of skin is numbed, a Jamshidi needle (a long, hollow needle) is inserted into the patient’s hip bone. Samples of blood, bone, and bone marrow are removed for examination under a microscope.[2]
References
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/diagnosis/?region=ab
- ↑ National Cancer Institute. Physician Data Query Database 2015.http://www.cancer.gov/types/leukemia/patient/cml-treatment-pdq