Post-streptococcal glomerulonephritis medical therapy: Difference between revisions
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*For mild to moderate hypertension: | *For mild to moderate hypertension: | ||
**Preferred regimen: Furosemide 1-3 mg/kg PO q24h | **Preferred regimen: Furosemide 1-3 mg/kg PO q24h | ||
*For treatment of rapidly progressive crescentic Acute post-streptococcal glomerulonephritis, following regimen is used | *For treatment of rapidly progressive crescentic Acute post-streptococcal glomerulonephritis, following regimen is used:<ref name="pmid20357732">{{cite journal |vauthors=Zaffanello M, Cataldi L, Franchini M, Fanos V |title=Evidence-based treatment limitations prevent any therapeutic recommendation for acute poststreptococcal glomerulonephritis in children |journal=Med. Sci. Monit. |volume=16 |issue=4 |pages=RA79–84 |date=April 2010 |pmid=20357732 |doi= |url=}}</ref> | ||
**Preferred regimen: Methylprednisolone | **Preferred regimen: Methylprednisolone | ||
Revision as of 19:11, 14 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]
Overview
Medical therapy
The mainstay of treatment is pharmacotherapy, however dietary therapy is useful for controlling edema and hypertension
Dietary therapy
- Low salt intake
- Low protein intake
- Water restrictions
Pharmacotherapy
- If streptococcal infection is still present, it should be treated with antibiotics[1]
- To control severe hypertension, following drugs can be used:
- Preferred regimen: Labetalol 0.5-2 mg/kg/h IV
- If refractory to labetalol then, Preferred regimen: Diazoxide or Nitroprusside 0.5-2 mcg/kg/min IV
- For mild to moderate hypertension:
- Preferred regimen: Furosemide 1-3 mg/kg PO q24h
- For treatment of rapidly progressive crescentic Acute post-streptococcal glomerulonephritis, following regimen is used:[2]
- Preferred regimen: Methylprednisolone
References
- ↑ Zoch-Zwierz W, Wasilewska A, Biernacka A, Tomaszewska B, Winiecka W, Wierciński R, Porowski T (2001). "[The course of post-streptococcal glomerulonephritis depending on methods of treatment for the preceding respiratory tract infection]". Wiad. Lek. (in Polish). 54 (1–2): 56–63. PMID 11344703.
- ↑ Zaffanello M, Cataldi L, Franchini M, Fanos V (April 2010). "Evidence-based treatment limitations prevent any therapeutic recommendation for acute poststreptococcal glomerulonephritis in children". Med. Sci. Monit. 16 (4): RA79–84. PMID 20357732.