Urethral cancer classification: Difference between revisions
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==Overview== | ==Overview== | ||
[[Urethral cancer|Urethra]]<nowiki/>l [[cancer]] may be classified according to cell types into 3 subtypes: [[transitional cell carcinoma]], [[squamous cell carcinoma]], and [[adenocarcinoma]]. It may also be classified into distal [[urethral]] [[cancer]], proximal urethral cancer and urethral cancer associated with invasive [[bladder cancer]]. | [[Urethral cancer|Urethra]]<nowiki/>l [[cancer]] may be classified according to [[cell]] types into 3 subtypes: [[transitional cell carcinoma]], [[squamous cell carcinoma]], and [[adenocarcinoma]]. It may also be classified into [[distal]] [[urethral]] [[cancer]], [[proximal]] [[Urethral cancer|urethral]] [[cancer]] and urethral cancer associated with invasive [[bladder cancer]]. | ||
==Classification== | ==Classification== | ||
===Based on histology=== | ===Based on histology=== | ||
In an analysis of Surveillance, Epidemiology, and End Results data from 1973 to 2002, the most common histologic types of [[Urethral cancer|urethral]] [[cancer]] were: | In an analysis of Surveillance, Epidemiology, and End Results data from 1973 to 2002, the most common [[histologic]] types of [[Urethral cancer|urethral]] [[cancer]] were: | ||
* [[Transitional cell]] (55%) | * [[Transitional cell]] (55%) | ||
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* [[Adenocarcinoma]] (16.4%) | * [[Adenocarcinoma]] (16.4%) | ||
Other cell types, such as [[melanoma]], were extremely rare. | Other [[cell]] types, such as [[melanoma]], were extremely rare. | ||
===Based on location=== | ===Based on location=== | ||
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* [[Female]]: [[Lesions]] of the distal third of the [[urethra]] | * [[Female]]: [[Lesions]] of the distal third of the [[urethra]] | ||
* Male: Anterior, or penile, portion of the [[urethra]], including the meatus and pendulous urethra | * [[Male]]: Anterior, or penile, portion of the [[urethra]], including the [[meatus]] and pendulous [[urethra]] | ||
'''Proximal Urethral Cancer''' | '''Proximal Urethral Cancer''' | ||
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These [[lesions]] are often deeply invasive. | These [[lesions]] are often deeply invasive. | ||
* Female: Lesions not clearly limited to the distal third of the [[urethra]] | * [[Female]]: [[Lesions|Lesion]]<nowiki/>s not clearly limited to the distal third of the [[urethra]] | ||
* Male: Bulbomembranous and prostatic [[urethra]] | * [[Male]]: Bulbomembranous and [[prostatic]] [[urethra]] | ||
'''Urethral Cancer Associated with Invasive Bladder Cancer''' | '''Urethral Cancer Associated with Invasive Bladder Cancer''' | ||
Approximately 5% to 10% of men with [[cystectomy]] for [[bladder cancer]] may have or may develop urethral cancer distal to the [[urogenital diaphragm]]. | Approximately 5% to 10% of men with [[cystectomy]] for [[bladder cancer]] may have or may develop [[urethral]] [[cancer]] distal to the [[urogenital diaphragm]]. | ||
==References== | ==References== | ||
Revision as of 18:30, 15 May 2018
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Urethral cancer classification On the Web |
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Risk calculators and risk factors for Urethral cancer classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Vindhya BellamKonda, M.B.B.S [2]
Overview
Urethral cancer may be classified according to cell types into 3 subtypes: transitional cell carcinoma, squamous cell carcinoma, and adenocarcinoma. It may also be classified into distal urethral cancer, proximal urethral cancer and urethral cancer associated with invasive bladder cancer.
Classification
Based on histology
In an analysis of Surveillance, Epidemiology, and End Results data from 1973 to 2002, the most common histologic types of urethral cancer were:
- Transitional cell (55%)
- Squamous cell (21.5%)
- Adenocarcinoma (16.4%)
Other cell types, such as melanoma, were extremely rare.
Based on location
Distal Urethral Cancer [1]
These lesions are often superficial.
- Female: Lesions of the distal third of the urethra
- Male: Anterior, or penile, portion of the urethra, including the meatus and pendulous urethra
Proximal Urethral Cancer
These lesions are often deeply invasive.
- Female: Lesions not clearly limited to the distal third of the urethra
- Male: Bulbomembranous and prostatic urethra
Urethral Cancer Associated with Invasive Bladder Cancer
Approximately 5% to 10% of men with cystectomy for bladder cancer may have or may develop urethral cancer distal to the urogenital diaphragm.
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq