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==Other Imaging Findings==
==Other Imaging Findings==
Angiography and arteriograms help in identifying aneurysms in mesentry.<ref name="pmid11798986">{{cite journal |author=Hughes LB, Bridges SL |title=Polyarteritis nodosa and microscopic polyangiitis: etiologic and diagnostic considerations |journal=Curr Rheumatol Rep |volume=4 |issue=1 |pages=75–82 |year=2002 |month=February |pmid=11798986 |doi= |url=}}</ref>


<div align="left">
=== Arteriography ===
<gallery heights="150" widths="160">
* Arteriography is the best imaging study to diagnosis of PAN.
Image:Polyarteritis nodosa mesenteric artery arteriogram.jpg|Polyarteritis nodosa mesenteric artery arteriogram
* Findings on an arteriography diagnostic of PAN include:<ref name="pmid2892931">{{cite journal |vauthors=Ewald EA, Griffin D, McCune WJ |title=Correlation of angiographic abnormalities with disease manifestations and disease severity in polyarteritis nodosa |journal=J. Rheumatol. |volume=14 |issue=5 |pages=952–6 |date=October 1987 |pmid=2892931 |doi= |url=}}</ref>
Image:Polyarteritis nodosa liver arteriogram.jpg|Polyarteritis nodosa liver arteriogram
** Microaneurysms
</gallery>
*** Pathognomic finding seen in 60-80% patients.
</div>
*** Caused by rupture of a vessel wall due to necrotizing inflammatory process.
 
*** Most commonly seen at the branching points and bifurcations of arteries.
<div align="left">
*** Microaneurysms are usually more than 10 in number.  
<gallery heights="150" widths="160">
*** Size: 2-5mm
Image:Polyarteritis nodosa kidney arteriogram.jpg|Polyarteritis nodosa kidney arteriogram
** Saccular aneurysms
Image:Polyarteritis nodosa kidney arteriogram 2.jpg|Polyarteritis nodosa kidney arteriogram
*** Size: 1-5mm
</gallery>
*** Seen in small and medium sized vessels.
</div>
** Tortuous vessels showing:
 
*** Irregular lumina
==Sources==
*** Segmental luminal narrowing or dilatation
Images shown below are courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology [http://www.peir.net]
*** Infarctions
*** Vascular irregularity
*** Segmental occlusions
<div align="left"></div>


==References==
==References==

Revision as of 20:05, 21 May 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Cafer Zorkun, M.D., Ph.D. [2]; Haritha Machavarapu, M.B.B.S.

Overview

Other Imaging Findings

Arteriography

  • Arteriography is the best imaging study to diagnosis of PAN.
  • Findings on an arteriography diagnostic of PAN include:[1]
    • Microaneurysms
      • Pathognomic finding seen in 60-80% patients.
      • Caused by rupture of a vessel wall due to necrotizing inflammatory process.
      • Most commonly seen at the branching points and bifurcations of arteries.
      • Microaneurysms are usually more than 10 in number.
      • Size: 2-5mm
    • Saccular aneurysms
      • Size: 1-5mm
      • Seen in small and medium sized vessels.
    • Tortuous vessels showing:
      • Irregular lumina
      • Segmental luminal narrowing or dilatation
      • Infarctions
      • Vascular irregularity
      • Segmental occlusions

References

  1. Ewald EA, Griffin D, McCune WJ (October 1987). "Correlation of angiographic abnormalities with disease manifestations and disease severity in polyarteritis nodosa". J. Rheumatol. 14 (5): 952–6. PMID 2892931.

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