Acoustic neuroma classification: Difference between revisions
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*Intracranial extension without [[brain stem]] distortion: intracranial portion of the tumor is 1.5-2.5 cm. (Some references mentioned 1-2 cm) | *Intracranial extension without [[brain stem]] distortion: intracranial portion of the tumor is 1.5-2.5 cm. (Some references mentioned 1-2 cm) | ||
*Intracranial extension with brain stem distortion: intracranial portion of the tumor is greater than 2.5 cm. (Some references mentioned more than 2 cm) | *Intracranial extension with brain stem distortion: intracranial portion of the tumor is greater than 2.5 cm. (Some references mentioned more than 2 cm) | ||
[[File:Acoustic neuroma.jpg|alt=Entirely intracanalicular (top) Intracranial extension without brainstem distortion (middle) Intracranial extension with brainstem distortion (bottom) | [[File:Acoustic neuroma.jpg|alt=Entirely intracanalicular (top) Intracranial extension without brainstem distortion (middle) Intracranial extension with brainstem distortion (bottom)|thumb|308x308px|Entirely intracanalicular (top) Intracranial extension without brainstem distortion (middle) Intracranial extension with brainstem distortion (bottom) | ||
photo from <nowiki>https://mayfieldclinic.com</nowiki> | photo from <nowiki>https://mayfieldclinic.com</nowiki> | ||
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Based on microscopic [[histopathology]], acoustic neuroma can be classified into four subtypes:<ref name="pmid12792904">{{cite journal| author=Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM| title=The pathobiologic spectrum of Schwannomas. | journal=Histol Histopathol | year= 2003 | volume= 18 | issue= 3 | pages= 925-34 | pmid=12792904 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12792904 }} </ref> | Based on microscopic [[histopathology]], acoustic neuroma can be classified into four subtypes:<ref name="pmid12792904">{{cite journal| author=Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM| title=The pathobiologic spectrum of Schwannomas. | journal=Histol Histopathol | year= 2003 | volume= 18 | issue= 3 | pages= 925-34 | pmid=12792904 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12792904 }} </ref> | ||
Revision as of 14:42, 22 May 2018
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Acoustic neuroma Microchapters | |
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Diagnosis | |
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Treatment | |
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Acoustic neuroma classification On the Web | |
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American Roentgen Ray Society Images of Acoustic neuroma classification | |
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Risk calculators and risk factors for Acoustic neuroma classification | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Simrat Sarai, M.D. [2]
Overview
Acoustic neuroma may be classified into several subtypes based on MRI scan, microscopic histopathology, and whether or not they are associated with neurofibromatosis type 2. Acoustic neuroma may be classified based on MRI scan into three subtypes: entirely canalicular, intracranial extension without brainstem distortion, and intracranial extension with brain stem distortion. Based on microscopic histopathology, acoustic neuroma may be classified into four subtypes: conventional schwannoma, cellular schwannoma, plexiform schwannoma, and melanotic schwannoma.[1]
Classification
Acoustic neuroma may be classified into two subtypes, based on whether or not they are associated with neurofibromatosis type 2.
- Sporadic
- The vast majority are the sporadic form. Ninety five % of all cases of acoustic neuroma are sporadic. The cause of sporadic form is unclear.
- Acoustic neuroma associated with neurofibromatosis type II (NF2)
- NF2 is a rare disorder and it accounts for 5% of acoustic neuromas.
Based on the MRI scan, acoustic neuromas can be classified into three subtypes:
- Entirely intracanalicular: The entire tumor is completely within the bony canal
- Intracranial extension without brain stem distortion: intracranial portion of the tumor is 1.5-2.5 cm. (Some references mentioned 1-2 cm)
- Intracranial extension with brain stem distortion: intracranial portion of the tumor is greater than 2.5 cm. (Some references mentioned more than 2 cm)
Based on microscopic histopathology, acoustic neuroma can be classified into four subtypes:[2]
- Conventional schwannoma: It is the most common schwannoma.
- Cellular schwannoma: It may mimic malignant peripheral nerve sheath tumor.
- Plexiform schwannoma: It may mimic malignant peripheral nerve sheath tumor if cellular- especially in childhood.
Plexiform schwannoma with high magnifaction - Melanotic schwannoma: It may be confused with melanoma.
Psammomatous melanotic schwannoma
It is associated with psammomatous form (psammomatous melanotic schwannoma) and with a heritable disorder (Carney complex). The Carney complex, also known as Carney syndrome, NAME syndrome and LAMB syndrome, is an autosomal dominant syndrome associated with endocrinopathy, endocrine and nonendocrine tumors, and spotty pigmentation of the skin including the following:[1]
- Cutaneous lentigines
- Myxomas (skin (subcutaneous), subcutanous, heart)
- Endocrine neoplasms
References
- ↑ 1.0 1.1 Schwannoma. Librepathology(2015) http://librepathology.org/wiki/index.php/Schwannoma Accessed on October 2 2015
- ↑ Kurtkaya-Yapicier O, Scheithauer B, Woodruff JM (2003). "The pathobiologic spectrum of Schwannomas". Histol Histopathol. 18 (3): 925–34. PMID 12792904.