Osteosarcoma epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. It is the 8<sup>th</sup> leading [[cancer]] in children under age 15, comprising 2.4% of all malignancies in [[pediatric]] patients and about 20% of all primary bone cancers. The overall incidence of osteosarcoma in U.S. population under 24 years of age are estimated at 0.44 cases for 100,000 individuals. | Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone [[malignancies]]. It is the 8<sup>th</sup> leading [[cancer]] in children under age 15, comprising 2.4% of all malignancies in [[pediatric]] patients and about 20% of all primary bone cancers. The overall [[incidence]] of osteosarcoma in U.S. population under 24 years of age are estimated at 0.44 cases for 100,000 individuals. Osteosarcoma is slightly more common in males than in females. Primary osteosarcoma typically occurs in young patients (10-20 years) with 75% occurring before the age of 20. Secondary osteosarcoma occurs in elderly patients. | ||
== | ==Epidemiology and Demographics== | ||
*Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. | *Osteosarcoma is the most common type of [[malignant]] bone cancer, accounting for 35% of primary [[bone malignancies]]. | ||
*Osteosarcoma is the 8<sup>th</sup> leading [[cancer]] in children under age 15, comprising 2.4% of all malignancies in [[pediatric]] patients and about 20% of all primary bone cancers. | *Osteosarcoma is the 8<sup>th</sup> leading [[cancer]] in children under age 15, comprising 2.4% of all [[malignancies]] in [[pediatric]] patients and about 20% of all primary bone cancers. | ||
*A second peak in incidence occurs in the elderly, usually associated with an underlying bone pathology such as [[Paget's disease of bone|Paget's disease]], medullary infarct, or prior [[irradiation]]. | *A second peak in incidence occurs in the elderly, usually associated with an underlying bone pathology such as [[Paget's disease of bone|Paget's disease]], medullary infarct, or prior [[irradiation]]. | ||
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==Location== | ==Location== | ||
*Osteosarcoma originates more frequently in the [[metaphysis|metaphyseal]] region of tubular long bones, with 42% occurring in the femur, 19% in the tibia, 10% in the humerus, 8% in the skull and jaw, and another 8% in the pelvis. | *Osteosarcoma originates more frequently in the [[metaphysis|metaphyseal]] region of tubular [[long bones]], with 42% occurring in the [[femur]], 19% in the [[tibia]], 10% in the [[humerus]], 8% in the [[skull]] and [[jaw]], and another 8% in the [[pelvis]]. | ||
==Gender== | ==Gender== | ||
Revision as of 15:19, 29 May 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
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Osteosarcoma epidemiology and demographics On the Web |
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Risk calculators and risk factors for Osteosarcoma epidemiology and demographics |
Overview
Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. It is the 8th leading cancer in children under age 15, comprising 2.4% of all malignancies in pediatric patients and about 20% of all primary bone cancers. The overall incidence of osteosarcoma in U.S. population under 24 years of age are estimated at 0.44 cases for 100,000 individuals. Osteosarcoma is slightly more common in males than in females. Primary osteosarcoma typically occurs in young patients (10-20 years) with 75% occurring before the age of 20. Secondary osteosarcoma occurs in elderly patients.
Epidemiology and Demographics
- Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies.
- Osteosarcoma is the 8th leading cancer in children under age 15, comprising 2.4% of all malignancies in pediatric patients and about 20% of all primary bone cancers.
- A second peak in incidence occurs in the elderly, usually associated with an underlying bone pathology such as Paget's disease, medullary infarct, or prior irradiation.
Incidence
- The overall incidence of osteosarcoma in U.S. population under 24 years of age are estimated at 0.44 cases for 100,000 individuals.[1]
Location
- Osteosarcoma originates more frequently in the metaphyseal region of tubular long bones, with 42% occurring in the femur, 19% in the tibia, 10% in the humerus, 8% in the skull and jaw, and another 8% in the pelvis.
Gender
- Osteosarcoma is slightly more common in males (5.4 per million per year) than in females (4.0 per million per year).
Age
- Primary osteosarcoma typically occurs in young patients (10-20 years) with 75% occurring before the age of 20.
- Secondary osteosarcoma occurs in elderly patients.
References
- ↑ Osteosarcoma. National cancer institute. http://www.cancer.gov/types/bone/hp/osteosarcoma-treatment-pdq