Osteosarcoma risk factors: Difference between revisions
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==Overview== | ==Overview== | ||
Common risk factors in the development of osteosarcoma are radiation to bones, [[alkylating antineoplastic agents]], [[Paget disease]], multiple hereditary [[osteochondromas]], [[fibrous dysplasia]], [[Bloom syndrome]],[[Rothmund-Thomson syndrome]], and [[Li-Fraumeni syndrome]]. | Common risk factors in the development of osteosarcoma are [[Radiation therapy|radiation]] to bones, [[alkylating antineoplastic agents]], [[Paget disease]], multiple hereditary [[osteochondromas]], [[fibrous dysplasia]], [[Bloom syndrome]],[[Rothmund-Thomson syndrome]], and [[Li-Fraumeni syndrome]]. | ||
==Risk Factors== | ==Risk Factors== | ||
Common risk factors in development of osteosarcoma are: | Common risk factors in development of osteosarcoma are: | ||
*Age and height: data suggest that the risk of osteosarcoma is highest during the teenage "growth spurt." Children with osteosarcoma are usually tall for their age | *[[Age]] and [[height]]: data suggest that the risk of osteosarcoma is highest during the teenage "[[growth spurt]]." Children with osteosarcoma are usually tall for their age | ||
*Radiation to bones: people who were treated with [[radiation]] for another cancer have a higher risk of later developing post-radiation (after radiation) osteosarcoma | *[[Radiation therapy|Radiation]] to bones: people who were treated with [[radiation]] for another cancer have a higher risk of later developing post-radiation (after radiation) osteosarcoma | ||
*Drugs: past treatment with anticancer drugs called [[alkylating antineoplastic agents]] | *Drugs: past treatment with anticancer drugs called [[alkylating antineoplastic agents]] | ||
*Certain bone diseases: | *Certain bone diseases: | ||
:*[[Paget disease]] of bone | :*[[Paget disease]] of bone | ||
:*Multiple hereditary [[osteochondromas]] | :*Multiple hereditary [[osteochondromas]] | ||
:*[[Fibrous dysplasia]] | :*[[Fibrous dysplasia]] | ||
:*Enchondromtosis | :*Enchondromtosis | ||
*Inherited cancer syndromes: Genetic diseases that predispose to osteosarcoma are:<ref name=radio2> Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma</ref> | *Inherited cancer syndromes: Genetic diseases that predispose to osteosarcoma are:<ref name="radio2">Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma</ref> | ||
:*[[Bloom syndrome]] | :*[[Bloom syndrome]] | ||
:*[[Diamond-Blackfan anemia]] | :*[[Diamond-Blackfan anemia]] | ||
Revision as of 15:22, 29 May 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Suveenkrishna Pothuru, M.B,B.S. [2]
Overview
Common risk factors in the development of osteosarcoma are radiation to bones, alkylating antineoplastic agents, Paget disease, multiple hereditary osteochondromas, fibrous dysplasia, Bloom syndrome,Rothmund-Thomson syndrome, and Li-Fraumeni syndrome.
Risk Factors
Common risk factors in development of osteosarcoma are:
- Age and height: data suggest that the risk of osteosarcoma is highest during the teenage "growth spurt." Children with osteosarcoma are usually tall for their age
- Radiation to bones: people who were treated with radiation for another cancer have a higher risk of later developing post-radiation (after radiation) osteosarcoma
- Drugs: past treatment with anticancer drugs called alkylating antineoplastic agents
- Certain bone diseases:
- Paget disease of bone
- Multiple hereditary osteochondromas
- Fibrous dysplasia
- Enchondromtosis
- Inherited cancer syndromes: Genetic diseases that predispose to osteosarcoma are:[1]
References
- ↑ Osteosarcoma. Dr Amir Rezaee ◉ and Dr Frank Gaillard ◉ et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/osteosarcoma