Wilms' tumor causes: Difference between revisions
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* Genetic mutations: <ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq </ref> | * Genetic mutations: <ref name="cancergov">National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq </ref> | ||
** Wilms tumor 1 gene (WT1) | ** Wilms tumor 1 gene (WT1) | ||
** WT2 | ** WT2<ref name="pmid9441738">{{cite journal |vauthors=Crider-Miller SJ, Reid LH, Higgins MJ, Nowak NJ, Shows TB, Futreal PA, Weissman BE |title=Novel transcribed sequences within the BWS/WT2 region in 11p15.5: tissue-specific expression correlates with cancer type |journal=Genomics |volume=46 |issue=3 |pages=355–63 |date=December 1997 |pmid=9441738 |doi=10.1006/geno.1997.5061 |url=}}</ref> | ||
** WTX | ** WTX | ||
Revision as of 22:27, 30 May 2018
Wilms' tumor Microchapters |
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Wilms' tumor causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shanshan Cen, M.D. [2]
Overview
Wilms' tumor may be caused by either genetic mutations or chromosomal alterations.
Causes
- Other genes and chromosomal alterations:
- 1q
- 16q and 1p
- CACNA1E
- 7p21
- SKCG-1
- TP53 (tumor suppressor gene)
- FBXW7
- PTCH1
- DICER1
- MYCN
References
- ↑ National Cancer Institute. Physician Data Query Database 2015. http://www.cancer.gov/publications/pdq
- ↑ Crider-Miller SJ, Reid LH, Higgins MJ, Nowak NJ, Shows TB, Futreal PA, Weissman BE (December 1997). "Novel transcribed sequences within the BWS/WT2 region in 11p15.5: tissue-specific expression correlates with cancer type". Genomics. 46 (3): 355–63. doi:10.1006/geno.1997.5061. PMID 9441738.