Polycystic kidney disease history and symptoms: Difference between revisions

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{{Polycystic kidney disease}}
{{Polycystic kidney disease}}
{{CMG}} {{AE}} [[User:Sergekorjian|Serge Korjian]],[[User:YazanDaaboul|Yazan Daaboul]]
{{CMG}} {{AE}} {{MKA}} [[User:Sergekorjian|Serge Korjian]],[[User:YazanDaaboul|Yazan Daaboul]]


==Overview==
==Overview==
Common clues for ADPKD on history include flank or back pain, nocturia and polyuria, headache and family history of renal failure or diagnosed renal cystic diseases.
The hallmark of polycystic kidney disease is flank or back pain. A positive family history of renal failure, cystic diseases, intracranial aneurysms is suggestive of polycystic kidney disease. The most common symptoms of polycystic kidney disease include hematuria, polyuria, nocturia and hypertension.


==History==
==History and Symptoms==
''Early ADPKD is asymptomatic and clinical diagnosis is usually with family history and imaging. Common symptoms at presentation include:''<ref name="pmid8321262">{{cite journal| author=Gabow PA| title=Autosomal dominant polycystic kidney disease. | journal=N Engl J Med | year= 1993 | volume= 329 | issue= 5 | pages= 332-42 | pmid=8321262 | doi=10.1056/NEJM199307293290508 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8321262 }} </ref><ref name="pmid17434405">{{cite journal| author=Torres VE, Harris PC, Pirson Y| title=Autosomal dominant polycystic kidney disease. | journal=Lancet | year= 2007 | volume= 369 | issue= 9569 | pages= 1287-301 | pmid=17434405 | doi=10.1016/S0140-6736(07)60601-1 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17434405 }} </ref>
*The hallmark of polycystic kidney disease is flank or back pain. A positive family history of renal failure, cystic diseases, intracranial aneurysms is suggestive of polycystic kidney disease. The most common symptoms of polycystic kidney disease include hematuria, polyuria, nocturia and hypertension.
* '''Flank/Back pain''' due to an enlarging cyst, cyst infection or hemorrhage, nephrolithiasis, and pyelonephritis.
* '''Headache''' due to hypertension
* '''Polyuria and nocturia''' due to loss of concentrating ability
* '''Hematuria'''
* '''Dyspnea, early satiety, and obstructive jaundice''' due to enlarging hepatic cysts
<br>
''Other important clues on history include:''
* Detailed family history of renal failure and cystic diseases
* Detailed family history of intracranial aneurysms and aneurysmal rupture to assess patient risk


==History and Symptoms==
*The majority of patients with [disease name] are asymptomatic.
OR
*The hallmark of [disease name] is [finding]. A positive history of [finding 1] and [finding 2] is suggestive of [disease name]. The most common symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3].
*Symptoms of [disease name] include [symptom 1], [symptom 2], and [symptom 3]. 
===History===
===History===
Patients with polycystic kidney disease may have a positive history of:
Patients with polycystic kidney disease may have a positive history of:<ref name="pmid8321262">{{cite journal| author=Gabow PA| title=Autosomal dominant polycystic kidney disease. | journal=N Engl J Med | year= 1993 | volume= 329 | issue= 5 | pages= 332-42 | pmid=8321262 | doi=10.1056/NEJM199307293290508 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8321262 }} </ref>
*Fatigue/weakness/malaise
*Fatigue/weakness/malaise
*Blood in urine
*Blood in urine
*Flank/back pain
*Flank/back pain
*Headache from hypertension
*Headache from hypertension
*Family history of renal failure or cystic diseases
*Family history of renal failure or diagnosed renal cystic diseases
*Family history of intracranial or abdominal aortic aneurysms
*Family history of intracranial or abdominal aortic aneurysms


===Common Symptoms===
===Common Symptoms===
Common symptoms of polycystic kidney disease include:
Common symptoms of polycystic kidney disease include:<ref name="pmid17434405">{{cite journal| author=Torres VE, Harris PC, Pirson Y| title=Autosomal dominant polycystic kidney disease. | journal=Lancet | year= 2007 | volume= 369 | issue= 9569 | pages= 1287-301 | pmid=17434405 | doi=10.1016/S0140-6736(07)60601-1 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17434405 }} </ref>
*Flank/back pain
*Flank/back pain
*Hematuria
*Hematuria
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[[Category:Up-To-Date]]
[[Category:Primary care]]
[[Category:Medicine]]
[[Category:Nephrology]]

Revision as of 16:18, 31 May 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2] Serge Korjian,Yazan Daaboul

Overview

The hallmark of polycystic kidney disease is flank or back pain. A positive family history of renal failure, cystic diseases, intracranial aneurysms is suggestive of polycystic kidney disease. The most common symptoms of polycystic kidney disease include hematuria, polyuria, nocturia and hypertension.

History and Symptoms

  • The hallmark of polycystic kidney disease is flank or back pain. A positive family history of renal failure, cystic diseases, intracranial aneurysms is suggestive of polycystic kidney disease. The most common symptoms of polycystic kidney disease include hematuria, polyuria, nocturia and hypertension.

History

Patients with polycystic kidney disease may have a positive history of:[1]

  • Fatigue/weakness/malaise
  • Blood in urine
  • Flank/back pain
  • Headache from hypertension
  • Family history of renal failure or diagnosed renal cystic diseases
  • Family history of intracranial or abdominal aortic aneurysms

Common Symptoms

Common symptoms of polycystic kidney disease include:[2]

  • Flank/back pain
  • Hematuria
  • Hypertension
  • Polyuria
  • Nocturia

Less Common Symptoms

Less common symptoms of polycystic kidney disease include:

  • Dyspnea
  • Early satiety
  • Jaundice
  • Urinary tract infection
  • Pyelonephritis
  • Nephrolithiasis

References

  1. Gabow PA (1993). "Autosomal dominant polycystic kidney disease". N Engl J Med. 329 (5): 332–42. doi:10.1056/NEJM199307293290508. PMID 8321262.
  2. Torres VE, Harris PC, Pirson Y (2007). "Autosomal dominant polycystic kidney disease". Lancet. 369 (9569): 1287–301. doi:10.1016/S0140-6736(07)60601-1. PMID 17434405.

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