Polycystic kidney disease laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
Common laboratory findings in | Common laboratory findings in polycystic kidney disease are [[urinary]] abnormalities including reduction in [[concentration]] capacity, [[hypocitraturia]], [[hematuria]], and [[proteinuria]]. [[Hyperuricemia]] is also a common finding and is a risk factor for disease progression and [[ESRD]]. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
''Laboratory findings in | ''Laboratory findings in polycystic kidney disease are usually confined to [[urinary]] abnormalities, which include:'' <ref name="pmid8198379">{{cite journal| author=Fick GM, Gabow PA| title=Natural history of autosomal dominant polycystic kidney disease. | journal=Annu Rev Med | year= 1994 | volume= 45 | issue= | pages= 23-9 | pmid=8198379 | doi=10.1146/annurev.med.45.1.23 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8198379 }} </ref> | ||
* Reduction in maximal urine concentration after water deprivation and ADH administration (usually first manifestation of disease) | * Reduction in maximal [[urine]] [[concentration]] after water deprivation and [[ADH]] administration (usually first manifestation of disease) | ||
* Hypocitraturia in 65% on patients | * [[Hypocitraturia]] in 65% on patients | ||
* Hyperuricemia in 20% of patients | * [[Hyperuricemia]] in 20% of patients | ||
* Hyperoxaluria in 20% of patients | * [[Hyperoxaluria]] in 20% of patients | ||
* Low urine pH | * Low [[urine pH]] | ||
* Hematuria (microscopic or macroscopic) | * [[Hematuria]] ([[microscopic]] or [[macroscopic]]) | ||
* Proteinuria usually less than 1 g/day | * [[Proteinuria]] usually less than 1 g/day | ||
==References== | ==References== | ||
Revision as of 07:11, 7 June 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Serge Korjian,Yazan Daaboul
Overview
Common laboratory findings in polycystic kidney disease are urinary abnormalities including reduction in concentration capacity, hypocitraturia, hematuria, and proteinuria. Hyperuricemia is also a common finding and is a risk factor for disease progression and ESRD.
Laboratory Findings
Laboratory findings in polycystic kidney disease are usually confined to urinary abnormalities, which include: [1]
- Reduction in maximal urine concentration after water deprivation and ADH administration (usually first manifestation of disease)
- Hypocitraturia in 65% on patients
- Hyperuricemia in 20% of patients
- Hyperoxaluria in 20% of patients
- Low urine pH
- Hematuria (microscopic or macroscopic)
- Proteinuria usually less than 1 g/day
References
- ↑ Fick GM, Gabow PA (1994). "Natural history of autosomal dominant polycystic kidney disease". Annu Rev Med. 45: 23–9. doi:10.1146/annurev.med.45.1.23. PMID 8198379.