Wilms' tumor primary prevention: Difference between revisions
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==Overview== | ==Overview== | ||
There are no established measures for the primary prevention of wilms tumor. | There are no established measures for the primary prevention of wilms tumor. Some measures might help.Testing should be done in patients suffering from certain [[Syndrome|syndromes]] which are associated with wilms tumor to detect them early. If a patient is suffering from [[Denys-Drash syndrome]] then prophylactic bilateral [[nephrectomy]] may be considered.<ref name="pmid16217371" /> | ||
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==Primary Prevention== | ==Primary Prevention== | ||
*There are no established measures for the primary prevention of wilms tumor. | *There are no established measures for the primary prevention of wilms tumor. | ||
*Some measures that might help are:- | *Some measures that might help are:- | ||
**Testing should be done in patients suffering from certain syndromes which are associated with wilms tumor to | **Testing should be done in patients suffering from certain syndromes which are associated with wilms tumor to detect them early.<ref name="pmid8095320">{{cite journal |vauthors=Green DM, Breslow NE, Beckwith JB, Norkool P |title=Screening of children with hemihypertrophy, aniridia, and Beckwith-Wiedemann syndrome in patients with Wilms tumor: a report from the National Wilms Tumor Study |journal=Med. Pediatr. Oncol. |volume=21 |issue=3 |pages=188–92 |date=1993 |pmid=8095320 |doi= |url=}}</ref><ref name="pmid11568898">{{cite journal |vauthors=McNeil DE, Brown M, Ching A, DeBaun MR |title=Screening for Wilms tumor and hepatoblastoma in children with Beckwith-Wiedemann syndromes: a cost-effective model |journal=Med. Pediatr. Oncol. |volume=37 |issue=4 |pages=349–56 |date=October 2001 |pmid=11568898 |doi= |url=}}</ref> | ||
**[[Genetic counseling|Genetic counselling]] may be of some help to parents with a family history of wilms tumor.<ref name="pmid12580371">{{cite journal |vauthors=Pakakasama S, Tomlinson GE |title=Genetic predisposition and screening in pediatric cancer |journal=Pediatr. Clin. North Am. |volume=49 |issue=6 |pages=1393–413 |date=December 2002 |pmid=12580371 |doi= |url=}}</ref> | **[[Genetic counseling|Genetic counselling]] may be of some help to parents with a family history of wilms tumor.<ref name="pmid12580371">{{cite journal |vauthors=Pakakasama S, Tomlinson GE |title=Genetic predisposition and screening in pediatric cancer |journal=Pediatr. Clin. North Am. |volume=49 |issue=6 |pages=1393–413 |date=December 2002 |pmid=12580371 |doi= |url=}}</ref> | ||
**If a patient is suffering from [[Denys-Drash syndrome]] then prophylactic bilateral [[nephrectomy]] may be considered.<ref name="pmid16217371">{{cite journal |vauthors=Breslow NE, Collins AJ, Ritchey ML, Grigoriev YA, Peterson SM, Green DM |title=End stage renal disease in patients with Wilms tumor: results from the National Wilms Tumor Study Group and the United States Renal Data System |journal=J. Urol. |volume=174 |issue=5 |pages=1972–5 |date=November 2005 |pmid=16217371 |pmc=1483840 |doi=10.1097/01.ju.0000176800.00994.3a |url=}}</ref> | **If a patient is suffering from [[Denys-Drash syndrome]] then prophylactic bilateral [[nephrectomy]] may be considered.<ref name="pmid16217371">{{cite journal |vauthors=Breslow NE, Collins AJ, Ritchey ML, Grigoriev YA, Peterson SM, Green DM |title=End stage renal disease in patients with Wilms tumor: results from the National Wilms Tumor Study Group and the United States Renal Data System |journal=J. Urol. |volume=174 |issue=5 |pages=1972–5 |date=November 2005 |pmid=16217371 |pmc=1483840 |doi=10.1097/01.ju.0000176800.00994.3a |url=}}</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
There are no established measures for the primary prevention of wilms tumor. Some measures might help.Testing should be done in patients suffering from certain syndromes which are associated with wilms tumor to detect them early. If a patient is suffering from Denys-Drash syndrome then prophylactic bilateral nephrectomy may be considered.[1]
Primary Prevention
- There are no established measures for the primary prevention of wilms tumor.
- Some measures that might help are:-
- Testing should be done in patients suffering from certain syndromes which are associated with wilms tumor to detect them early.[2][3]
- Genetic counselling may be of some help to parents with a family history of wilms tumor.[4]
- If a patient is suffering from Denys-Drash syndrome then prophylactic bilateral nephrectomy may be considered.[1]
References
- ↑ 1.0 1.1 Breslow NE, Collins AJ, Ritchey ML, Grigoriev YA, Peterson SM, Green DM (November 2005). "End stage renal disease in patients with Wilms tumor: results from the National Wilms Tumor Study Group and the United States Renal Data System". J. Urol. 174 (5): 1972–5. doi:10.1097/01.ju.0000176800.00994.3a. PMC 1483840. PMID 16217371.
- ↑ Green DM, Breslow NE, Beckwith JB, Norkool P (1993). "Screening of children with hemihypertrophy, aniridia, and Beckwith-Wiedemann syndrome in patients with Wilms tumor: a report from the National Wilms Tumor Study". Med. Pediatr. Oncol. 21 (3): 188–92. PMID 8095320.
- ↑ McNeil DE, Brown M, Ching A, DeBaun MR (October 2001). "Screening for Wilms tumor and hepatoblastoma in children with Beckwith-Wiedemann syndromes: a cost-effective model". Med. Pediatr. Oncol. 37 (4): 349–56. PMID 11568898.
- ↑ Pakakasama S, Tomlinson GE (December 2002). "Genetic predisposition and screening in pediatric cancer". Pediatr. Clin. North Am. 49 (6): 1393–413. PMID 12580371.