Myeloproliferative neoplasm risk factors: Difference between revisions
Jump to navigation
Jump to search
Shyam Patel (talk | contribs) |
Shyam Patel (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{Myeloproliferative disease}} | {{Myeloproliferative disease}} | ||
{{CMG}}{{AE}} {{MJK}} | {{CMG}}{{AE}} {{MJK}} {{shyam}} | ||
==Overview== | ==Overview== | ||
There are no established risk factors for myeloproliferative neoplasm. | There are no established risk factors for myeloproliferative neoplasm. | ||
==Risk factors== | ==Risk factors== | ||
*'''Age''': Age is a major risk factor for the development of myeloproliferative neoplasm. Aging is associated with the acquisition of mutations in cells, and these mutations can lead to the development of hematologic malignancies. | |||
*'''Autoimmunity''': A prior history of autoimmune disease is associated with a risk for developing myeloproliferative neoplasms.<ref name="pmid20053870">{{cite journal| author=Kristinsson SY, Landgren O, Samuelsson J, Björkholm M, Goldin LR| title=Autoimmunity and the risk of myeloproliferative neoplasms. | journal=Haematologica | year= 2010 | volume= 95 | issue= 7 | pages= 1216-20 | pmid=20053870 | doi=10.3324/haematol.2009.020412 | pmc=2895049 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20053870 }} </ref> There is specifically an increased risk of myeloproliferative neoplasm is patients with: | *'''Autoimmunity''': A prior history of autoimmune disease is associated with a risk for developing myeloproliferative neoplasms.<ref name="pmid20053870">{{cite journal| author=Kristinsson SY, Landgren O, Samuelsson J, Björkholm M, Goldin LR| title=Autoimmunity and the risk of myeloproliferative neoplasms. | journal=Haematologica | year= 2010 | volume= 95 | issue= 7 | pages= 1216-20 | pmid=20053870 | doi=10.3324/haematol.2009.020412 | pmc=2895049 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20053870 }} </ref> There is specifically an increased risk of myeloproliferative neoplasm is patients with: | ||
**[[Crohn's disease]]: This carries a 2.9-fold increased risk. | **[[Crohn's disease]]: This carries a 2.9-fold increased risk. | ||
Revision as of 18:32, 19 June 2018
|
Myeloproliferative Neoplasm Microchapters |
|
Differentiating myeloproliferative neoplasm from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Myeloproliferative neoplasm risk factors On the Web |
|
American Roentgen Ray Society Images of Myeloproliferative neoplasm risk factors |
|
Directions to Hospitals Treating Myeloproliferative neoplasm |
|
Risk calculators and risk factors for Myeloproliferative neoplasm risk factors |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Shyam Patel [3]
Overview
There are no established risk factors for myeloproliferative neoplasm.
Risk factors
- Age: Age is a major risk factor for the development of myeloproliferative neoplasm. Aging is associated with the acquisition of mutations in cells, and these mutations can lead to the development of hematologic malignancies.
- Autoimmunity: A prior history of autoimmune disease is associated with a risk for developing myeloproliferative neoplasms.[1] There is specifically an increased risk of myeloproliferative neoplasm is patients with:
- Crohn's disease: This carries a 2.9-fold increased risk.
- Immune thrombocytopenia purpura: This carries a 1.8-fold increased risk.
- Polymyalgia rheumatica: This carries a 1.7-fold increased risk.
- Giant cell arteritis: This carries a 5.9-fold increased risk.
- Reiter's reactive arthritis: This carries a 15.9-fold increased risk.
- Aplastic anemia: This carries a 7.8-fold increased risk.
References
- ↑ Kristinsson SY, Landgren O, Samuelsson J, Björkholm M, Goldin LR (2010). "Autoimmunity and the risk of myeloproliferative neoplasms". Haematologica. 95 (7): 1216–20. doi:10.3324/haematol.2009.020412. PMC 2895049. PMID 20053870.