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==Differentiating Asymptomatic Bacteriuria From Other Diseases==
<includeonly>
Asymptomatic Bacteriuria must be differentiated from other diseases that might cause bacteriuria.<ref name="WiseLongo2015">{{cite journal|last1=Wise|first1=Gilbert J.|last2=Longo|first2=Dan L.|last3=Schlegel|first3=Peter N.|title=Sterile Pyuria|journal=New England Journal of Medicine|volume=372|issue=11|year=2015|pages=1048–1054|issn=0028-4793|doi=10.1056/NEJMra1410052}}</ref><ref name="Stamm1983">{{cite journal|last1=Stamm|first1=Walter E.|title=Measurement of pyuria and its relation to bacteriuria|journal=The American Journal of Medicine|volume=75|issue=1|year=1983|pages=53–58|issn=00029343|doi=10.1016/0002-9343(83)90073-6}}</ref><ref name="GroahPerez-Losada2015">{{cite journal|last1=Groah|first1=Suzanne|last2=Perez-Losada|first2=Marcos|last3=Caldovic|first3=Ljubica|last4=Ljungberg|first4=Inger|last5=Sprague|first5=Bruce|last6=Castro-Nallar|first6=Eduardo|last7=Shah|first7=Neel|last8=Hsieh|first8=Michael|last9=Pohl|first9=Hans|title=MP20-08 PYURIA AND ASYMPTOMATIC BACTERIURIA IS ASSOCIATED WITH NOVEL AND SPECIFIC URINE MICROBIOMES|journal=The Journal of Urology|volume=193|issue=4|year=2015|pages=e226|issn=00225347|doi=10.1016/j.juro.2015.02.980}}</ref><ref name="ShaikhShope2016">{{cite journal|last1=Shaikh|first1=N.|last2=Shope|first2=T. R.|last3=Hoberman|first3=A.|last4=Vigliotti|first4=A.|last5=Kurs-Lasky|first5=M.|last6=Martin|first6=J. M.|title=Association Between Uropathogen and Pyuria|journal=PEDIATRICS|volume=138|issue=1|year=2016|pages=e20160087–e20160087|issn=0031-4005|doi=10.1542/peds.2016-0087}}</ref>
<script type="text/javascript">
 
function calcScore(){
'''To review differential diagnosis of pyuria, click [[Pyuria#Pyuria Differential Diagnosis|here]].'''
var score = 0;
 
if(document.forms["IMPROVEDDScore"]["input1"].checked == 1){
'''To review differential diagnosis of sterile pyuria, click [[Sterile pyuria differential diagnosis|here]].'''
score += 3;
{|
}
|- style="background: #4479BA; color: #FFFFFF; text-align: center;"
if(document.forms["IMPROVEDDScore"]["input2"].checked == 1){
! rowspan="5" |Category
score += 2;
! colspan="3" rowspan="5" |Disease
}
! colspan="9" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Clinical manifestations
if(document.forms["IMPROVEDDScore"]["input3"].checked == 1){
! colspan="8" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Para−clinical findings
score += 2;
! colspan="1" rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard for diagnosis
}
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
if(document.forms["IMPROVEDDScore"]["input4"].checked == 1){
|-
score += 2;
! colspan="7" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
}
! colspan="2" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical examination
if(document.forms["IMPROVEDDScore"]["input5"].checked == 1){
|-
score += 2;
! colspan="7" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Lab Findings
}
! rowspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
if(document.forms["IMPROVEDDScore"]["input6"].checked == 1){
|-
score += 1;
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Pain
}
! colspan="1" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
if(document.forms["IMPROVEDDScore"]["input7"].checked == 1){
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |N/V
score += 1;
! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Urinary symptoms
}
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
if(document.forms["IMPROVEDDScore"]["input8"].checked == 1){
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other
score += 1;
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |CBC
}
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Electrolytes
document.forms["IMPROVEDDScore"]["result"].value = score;
! colspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Urinalysis
if(score == 0){document.forms["IMPROVEDDScore"]["longanswer"].value = "Predicted VTE risk through 3 months is 0.4%";}
|-
if(score == 1){document.forms["IMPROVEDDScore"]["longanswer"].value = "Predicted VTE risk through 3 months is 0.6%";}
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Dysuria
if(score == 2){document.forms["IMPROVEDDScore"]["longanswer"].value = "Predicted VTE risk through 3 months is 0.8%";}
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Frequency
if(score == 3){document.forms["IMPROVEDDScore"]["longanswer"].value = "Predicted VTE risk through 3 months is 1.2%";}
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Urgency
if(score == 4){document.forms["IMPROVEDDScore"]["longanswer"].value = "Predicted VTE risk through 3 months is 1.6%";}
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gross hematuria
if(score >= 5 && score <= 10){document.forms["IMPROVEDDScore"]["longanswer"].value = "Predicted VTE risk through 3 months is 2.2%";}
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Cell
}
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Cast
</script>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bacteriuria
<form name="IMPROVEDDScore">
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Culture
<table>
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other
<tr><td>Prior episode of VTE</td><td><input type="checkbox" name="input1" value="3.0" onchange="calcScore();" /></td></tr>
|-
<tr><td>Thrombophilia</td><td><input type="checkbox" name="input2" value="2.0" onchange="calcScore();" /></td></tr>
! rowspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Infectious diseases
<tr><td>Paralysis of the lower extremity during the hospitalization</td><td><input type="checkbox" name="input3" value="2.0" onchange="calcScore();" /></td></tr>
! rowspan="4" align="center" style="background:#DCDCDC;" + |[[Urinary tract infection|UTI]]<ref name="pmid18061020">{{cite journal |vauthors=Neal DE |title=Complicated urinary tract infections |journal=Urol. Clin. North Am. |volume=35 |issue=1 |pages=13–22; v |date=February 2008 |pmid=18061020 |doi=10.1016/j.ucl.2007.09.010 |url=}}</ref>
<tr><td>Current malignancy</td><td><input type="checkbox" name="input4" value="2.0" onchange="calcScore();" /></td></tr>
! rowspan="3" align="center" style="background:#DCDCDC;" + |[[Bacteria|Bacterial]]
<tr><td>D-dimer ≥ 2x Upper Limit of Normal (ULN)</td><td><input type="checkbox" name="input5" value="2.0" onchange="calcScore();" /></td></tr>
! align="center" style="background:#DCDCDC;" + |[[Asymptomatic bacteriuria]]<ref name="Nicolle2014">{{cite journal|last1=Nicolle|first1=Lindsay E.|title=Asymptomatic bacteriuria|journal=Current Opinion in Infectious Diseases|volume=27|issue=1|year=2014|pages=90–96|issn=0951-7375|doi=10.1097/QCO.0000000000000019}}</ref><ref name="Nicolle2015">{{cite journal|last1=Nicolle|first1=Lindsay E.|title=Asymptomatic Bacteriuria and Bacterial Interference|journal=Microbiology Spectrum|volume=3|issue=5|year=2015|issn=2165-0497|doi=10.1128/microbiolspec.UTI-0001-2012}}</ref>
<tr><td>Immobilization for at least 7 days</td><td><input type="checkbox" name="input6" value="1.0" onchange="calcScore();" /></td></tr>
| align="center" style="background:#F5F5F5;" + |−
<tr><td>ICU or CCU admission</td><td><input type="checkbox" name="input7" value="1.0" onchange="calcScore();" /></td></tr>
| align="center" style="background:#F5F5F5;" + |−
<tr><td>Age more than 60 years</td><td><input type="checkbox" name="input8" value="1.0" onchange="calcScore();" /></td></tr>
| align="center" style="background:#F5F5F5;" + |−
</table>
| align="center" style="background:#F5F5F5;" + |−
Score: <input type="text" name="result" /><br />
| align="center" style="background:#F5F5F5;" + |−
<input type="text" size="80" name="longanswer" />
| align="center" style="background:#F5F5F5;" + |−
</form>
| align="center" style="background:#F5F5F5;" + |−
</includeonly>
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |±
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |NA
| align="center" style="background:#F5F5F5;" + |NA
| align="center" style="background:#F5F5F5;" + |[[Urine|Urinalysis]]
| align="left" style="background:#F5F5F5;" + |
*Increased risk in [[pregnancy]]
*Must be treated prior to an invasive urologic procedure
|-
! align="center" style="background:#DCDCDC;" + |[[Cystitis]]<ref name="pmid28613784">{{cite journal |vauthors=Sabih A, Leslie SW |title= |journal= |volume= |issue= |pages= |date= |pmid=28613784 |doi= |url=}}</ref>
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="left" style="background:#F5F5F5;" + |
*[[Nitrite]] +
*[[Leukocyte esterase]] +
| align="center" style="background:#F5F5F5;" + |NA
| align="center" style="background:#F5F5F5;" + |[[Urine|Urinalysis]]
| align="center" style="background:#F5F5F5;" + |NA
|-
! align="center" style="background:#DCDCDC;" + |[[Pyelonephritis]]<ref name="pmid28087935">{{cite journal |vauthors=Pietrucha-Dilanchian P, Hooton TM |title=Diagnosis, Treatment, and Prevention of Urinary Tract Infection |journal=Microbiol Spectr |volume=4 |issue=6 |pages= |date=December 2016 |pmid=28087935 |doi=10.1128/microbiolspec.UTI-0021-2015 |url=}}</ref>
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |
*[[Leukocytosis]]
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |WBC cast
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="left" style="background:#F5F5F5;" + |
*[[Nitrite]] +
*[[Leukocyte esterase]] +
| align="center" style="background:#F5F5F5;" + |NA
| align="center" style="background:#F5F5F5;" + |Clinical manifestation + [[Urine|urinalysis]]
| align="center" style="background:#F5F5F5;" + |NA
|-
! colspan="2" align="center" style="background:#DCDCDC;" + |[[Prostatitis]]<ref name="pmid23519458">{{cite journal |vauthors=Wagenlehner FM, Pilatz A, Bschleipfer T, Diemer T, Linn T, Meinhardt A, Schagdarsurengin U, Dansranjavin T, Schuppe HC, Weidner W |title=Bacterial prostatitis |journal=World J Urol |volume=31 |issue=4 |pages=711–6 |date=August 2013 |pmid=23519458 |doi=10.1007/s00345-013-1055-x |url=}}</ref>
| align="center" style="background:#F5F5F5;" + | Pelvic or perineal pain
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |Nl or ↑
| align="center" style="background:#F5F5F5;" + |
*Dribbling of urine
*Firm and tender [[prostate]]
| align="center" style="background:#F5F5F5;" + |
*[[Leukocytosis]]
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |±
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |
*Cloudy urine
*Positive [[Gram staining|gram stain]]
| align="center" style="background:#F5F5F5;" + |NA
| align="center" style="background:#F5F5F5;" + |Clinical manifestation + [[Urine|urinalysis]]
| align="center" style="background:#F5F5F5;" + |
*Increased risk of [[bacteremia]], prostatic abscess, and metastatic infection
*Might be acute or chronic infection
|-
! colspan="3" align="center" style="background:#DCDCDC;" + |[[Balanitis]]<ref name="pmid25596845">{{cite journal |vauthors=Hsu CY, Lin CL, Kao CH |title=Balanitis is a risk factor for herpes zoster |journal=Eur. J. Clin. Microbiol. Infect. Dis. |volume=34 |issue=5 |pages=985–90 |date=May 2015 |pmid=25596845 |doi=10.1007/s10096-015-2314-0 |url=}}</ref>
| align="center" style="background:#F5F5F5;" + |Penile pain
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |
*[[Pruritus]]
*Erythematous lesions on the glans and/or the foreskin
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |±
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |NA
| align="center" style="background:#F5F5F5;" + |NA
| align="center" style="background:#F5F5F5;" + |Clinical manifestation
| align="center" style="background:#F5F5F5;" + |
*Associated with [[reactive arthritis]]
|-
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Non−infectious diseases
! align="center" style="background:#DCDCDC;" + |[[Urinary tract|Urinary tract disorders]]
! colspan="2" align="center" style="background:#DCDCDC;" + |[[Urinary catheter|Urinary catheterization]]<ref name="ForsterHaslam2017">{{cite journal|last1=Forster|first1=C.S.|last2=Haslam|first2=D.B.|last3=Jackson|first3=E.|last4=Goldstein|first4=S.L.|title=Utility of a routine urinalysis in children who require clean intermittent catheterization|journal=Journal of Pediatric Urology|volume=13|issue=5|year=2017|pages=488.e1–488.e5|issn=14775131|doi=10.1016/j.jpurol.2017.01.016}}</ref>
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + |−
| align="left" style="background:#F5F5F5;" + |
*[[Leukocytosis]] ±
| align="center" style="background:#F5F5F5;" + |Nl
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + | +
| align="center" style="background:#F5F5F5;" + | +
| align="left" style="background:#F5F5F5;" + |
* [[Leukocyte esterase]] ±
| align="center" style="background:#F5F5F5;" + |−
| align="center" style="background:#F5F5F5;" + |Clinical manifestation + [[Urine|urinalysis]]
| align="left" style="background:#F5F5F5;" + |
*Predicting [[Urinary tract infection|UTI]] in children who required clean intermittent [[Catheter|catheterization]] by routine [[Urine|urinalysis]]
|-
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Disease
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Pain
! colspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Fever
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |N/V
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Dysuria
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Frequency
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Urgency
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gross hematuria
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |BP
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other PE
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |CBC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Electrolytes
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Cell
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Cast
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Bacteriuria
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Culture
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other UA findings
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Imaging
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard for diagnosis
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Associated findings
|}
<references />

Revision as of 16:30, 20 June 2018