Myeloproliferative neoplasm physical examination: Difference between revisions
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===Vital Signs=== | ===Vital Signs=== | ||
*[[Fever]] | *[[Fever]] | ||
*[[Tachycardia]] | |||
===Skin=== | ===Skin=== | ||
*[[ | *[[Ecchymoses]] | ||
*[[Petechiae]] | *[[Petechiae]] | ||
*[[Ulcers]] | *[[Ulcers]] | ||
*[[Vesicles]] | *[[Vesicles]] | ||
*[[Pallor]] | |||
===HEENT=== | ===HEENT=== | ||
*Decreased vision acuity | *Decreased vision acuity | ||
* | *Mucosal [[pallor]] | ||
===Neck=== | ===Neck=== | ||
Line 29: | Line 33: | ||
===Abdomen=== | ===Abdomen=== | ||
*[[Splenomegaly]] | *[[Splenomegaly]] | ||
*[[Hepatomegaly]] | |||
*Tenderness to palpation | |||
===Genitourinary=== | ===Genitourinary=== | ||
*[[lymphadenopathy|Inguinal lymphadenopathy]] (usually painless) | *[[lymphadenopathy|Inguinal lymphadenopathy]] (usually painless) |
Revision as of 21:38, 21 June 2018
Myeloproliferative Neoplasm Microchapters |
Differentiating myeloproliferative neoplasm from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Patients with myeloproliferative neoplasm are usually well-appearing. Physical examination of patients with chronic myelogenous leukemia is usually remarkable for skin bruising, fever, splenomegaly, and lymphadenopathy.[1]
Physical Examination
Common physical examination findings associated with myeloproliferative neoplasm include:[1][2][3][4]
Appearance of the Patient
- Patients are usually well-appearing at an early time point in the disease and ill-appearing at a later time point in the disease.
Vital Signs
Skin
HEENT
- Decreased vision acuity
- Mucosal pallor
Neck
Lungs
- Vesicular breath sounds
- Wheezing
Chest
- Axillary lymphadenopathy (usually painless)
Abdomen
- Splenomegaly
- Hepatomegaly
- Tenderness to palpation
Genitourinary
- Inguinal lymphadenopathy (usually painless)
- Scrotal swelling
- Priapism
References
- ↑ 1.0 1.1 Agarwal MB, Malhotra H, Chakrabarti P, Varma N, Mathews V, Bhattacharyya J; et al. (2015). "Myeloproliferative neoplasms working group consensus recommendations for diagnosis and management of primary myelofibrosis, polycythemia vera, and essential thrombocythemia". Indian J Med Paediatr Oncol. 36 (1): 3–16. doi:10.4103/0971-5851.151770. PMC 4363847. PMID 25810569.
- ↑ Tefferi A (2006). "Classification, diagnosis and management of myeloproliferative disorders in the JAK2V617F era". Hematology Am Soc Hematol Educ Program: 240–245. PMID 17124067.
- ↑ Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/signs-and-symptoms/?region=ab
- ↑ Bittencourt RI, Vassallo J, Chauffaille Mde L, Xavier SG, Pagnano KB, Nascimento AC; et al. (2012). "Philadelphia-negative chronic myeloproliferative neoplasms". Rev Bras Hematol Hemoter. 34 (2): 140–9. doi:10.5581/1516-8484.20120034. PMC 3459391. PMID 23049404.