Myeloproliferative neoplasm MRI: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Myeloproliferative disease}} | {{Myeloproliferative disease}} | ||
{{CMG}} {{AE}} {{MJK}} | {{CMG}} {{AE}} {{MJK}} {{shyam}} | ||
==Overview== | ==Overview== | ||
Brain MRI may be helpful in the detection of brain metastasis in patients with myeloproliferative neoplasm.<ref name="cancer.ca">Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/diagnosis/?region=ab</ref> | Brain MRI may be helpful in the detection of brain metastasis in patients with myeloproliferative neoplasm.<ref name="cancer.ca">Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/diagnosis/?region=ab</ref> | ||
==Brain MRI== | ==Brain MRI== | ||
MRI may be helpful in the detection of anatomic abnormalities in patients with myeloproliferative neoplasm. However, MRI is an expensive test and should be reserved for patients in whom CT or ultrasound are nondiagnostic. | |||
*'''[[Ischemia stroke]]''': MRI of the brain is the most sensitive test for assessment of cerebral vascular abnormalities associated with myeloproliferative neoplasm. Patients with myeloproliferative neoplasm frequently develop thrombotic complications such as ischemic stroke, especially for patients who are at high risk for thrombotic events, such as patients above the age of 60 and with a ''JAK2'' mutation.<ref name="cancer.ca">Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/diagnosis/?region=ab</ref><ref name="pmid11328338">{{cite journal| author=Koennecke HC, Bernarding J| title=Diffusion-weighted magnetic resonance imaging in two patients with polycythemia rubra vera and early ischemic stroke. | journal=Eur J Neurol | year= 2001 | volume= 8 | issue= 3 | pages= 273-7 | pmid=11328338 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11328338 }} </ref> | |||
*'''[[Mesenteric thrombosis]]''': MRI of the [[abdomen]] is the most sensitive test for assessment of thrombosis of the mesenteric vasculature, such as the [[portal vein]], [[splenic vein]], [[superior mesenteric vein]], or [[inferior mesenteric vein]]. | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 22:03, 23 June 2018
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Myeloproliferative Neoplasm Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2] Shyam Patel [3]
Overview
Brain MRI may be helpful in the detection of brain metastasis in patients with myeloproliferative neoplasm.[1]
Brain MRI
MRI may be helpful in the detection of anatomic abnormalities in patients with myeloproliferative neoplasm. However, MRI is an expensive test and should be reserved for patients in whom CT or ultrasound are nondiagnostic.
- Ischemia stroke: MRI of the brain is the most sensitive test for assessment of cerebral vascular abnormalities associated with myeloproliferative neoplasm. Patients with myeloproliferative neoplasm frequently develop thrombotic complications such as ischemic stroke, especially for patients who are at high risk for thrombotic events, such as patients above the age of 60 and with a JAK2 mutation.[1][2]
- Mesenteric thrombosis: MRI of the abdomen is the most sensitive test for assessment of thrombosis of the mesenteric vasculature, such as the portal vein, splenic vein, superior mesenteric vein, or inferior mesenteric vein.
References
- ↑ 1.0 1.1 Canadian Cancer Society.2015.http://www.cancer.ca/en/cancer-information/cancer-type/leukemia-chronic-myelogenous-cml/diagnosis/?region=ab
- ↑ Koennecke HC, Bernarding J (2001). "Diffusion-weighted magnetic resonance imaging in two patients with polycythemia rubra vera and early ischemic stroke". Eur J Neurol. 8 (3): 273–7. PMID 11328338.