Thrombocytopenia differential diagnosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Thrombocytopenia}} | {{Thrombocytopenia}} | ||
{{CMG}} | {{CMG}}; '''Associate Editor-In-Chief:''' [[User:Farbod Zahedi Tajrishi|Farbod Zahedi Tajrishi]] | ||
==Overview== | ==Overview== | ||
[[Thrombocytopenia]] has a broad range of potential causes. While a good [[History and Physical examination|history and physical examination]] can be helpful to diagnose some of these causes such as drug-induced thrombocytopenia, they usually don't suffice and further evaluation is often needed. There are also some useful points that may guide the [[physician]] to an appropriate [[diagnosis]]. For example, [[asymptomatic]], isolated [[thrombocytopenia]] most probably suggests [[Idiopathic thrombocytopenic purpura|ITP]], while [[thrombocytopenia]] in critically ill, hospitalized patients is usually suggestive of [[Iatrogenesis|iatrogenic]] causes (eg. [[dilution]]), [[platelet]] consumption, [[bone marrow suppression]] from [[infection]]/[[sepsis]], or even [[drug-induced thrombocytopenia]]. One should consider however, that a wide variety of other conditions such as [[autoimmune disorders]], [[nutrient]] deficiencies, [[thrombotic microangiopathies]] could all as well cause [[thrombocytopenia]]. | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revision as of 08:16, 7 July 2018
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Thrombocytopenia Microchapters |
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Thrombocytopenia differential diagnosis On the Web |
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Risk calculators and risk factors for Thrombocytopenia differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Farbod Zahedi Tajrishi
Overview
Thrombocytopenia has a broad range of potential causes. While a good history and physical examination can be helpful to diagnose some of these causes such as drug-induced thrombocytopenia, they usually don't suffice and further evaluation is often needed. There are also some useful points that may guide the physician to an appropriate diagnosis. For example, asymptomatic, isolated thrombocytopenia most probably suggests ITP, while thrombocytopenia in critically ill, hospitalized patients is usually suggestive of iatrogenic causes (eg. dilution), platelet consumption, bone marrow suppression from infection/sepsis, or even drug-induced thrombocytopenia. One should consider however, that a wide variety of other conditions such as autoimmune disorders, nutrient deficiencies, thrombotic microangiopathies could all as well cause thrombocytopenia.